BDBM967 5PhBuCOOH deriv.::Statine deriv. 50::Tle-Val-Sta::benzyl N-[(1S)-1-{[(2S,3R,4R)-4-{[(1S)-1-[(1H-1,3-benzodiazol-2-ylmethyl)carbamoyl]-2-methylpropyl]carbamoyl}-3-hydroxy-4-{[(4-methoxyphenyl)methyl]amino}-1-phenylbutan-2-yl]carbamoyl}-2,2-dimethylpropyl]carbamate

SMILES COc1ccc(CN[C@H]([C@H](O)[C@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)OCc2ccccc2)C(C)(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCc2nc3ccccc3[nH]2)cc1

InChI Key InChIKey=KBEORHYUNGNGSC-FSYSLULESA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 967   

TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sandoz Forschungsinstitut Ges.M.B.H.

Curated by ChEMBL
LigandPNGBDBM967(5PhBuCOOH deriv. | Statine deriv. 50 | Tle-Val-Sta...)
Affinity DataKi:  4.57nMAssay Description:Inhibitory activity was determined against HIV type 1 proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Sandoz Forschungsinstitut Ges.M.B.H.

LigandPNGBDBM967(5PhBuCOOH deriv. | Statine deriv. 50 | Tle-Val-Sta...)
Affinity DataKi:  4.60nMAssay Description:Enzymatic activity was measured by following cleavage of the substrate H-Lys-Ala-Arg-Val-Leu-pNph-Glu-Ala-Nle-NH2. Products of the cleavage reaction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDimer of Gag-Pol polyprotein [514-612](Human immunodeficiency virus type 2)
Sandoz Forschungsinstitut Ges.M.B.H.

LigandPNGBDBM967(5PhBuCOOH deriv. | Statine deriv. 50 | Tle-Val-Sta...)
Affinity DataKi:  52nMAssay Description:Enzymatic activity was measured by following cleavage of the substrate H-Lys-Ala-Arg-Val-Leu-pNph-Glu-Ala-Nle-NH2. Products of the cleavage reaction ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed