BDBM97501 Roche-Dataset for PDE10A, Compound 33::US8470820, 12

SMILES CN(C)CCn1nc(cc1NC(=O)c1nc(ccc1Nc1cncnc1)C1CC1)-c1ccccn1

InChI Key InChIKey=YQBHCXNSRTWRPM-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 97501   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM97501(Roche-Dataset for PDE10A, Compound 33 | US8470820,...)
Affinity DataIC50:  1.05nMAssay Description:Human PDE10A IC50 values were determined by using purified enzyme (Biomol cat. # SE-534) in a scintillation proximity assay (SPA) in 96 well plates (...More data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
F. Hoffmann-La Roche

LigandPNGBDBM97501(Roche-Dataset for PDE10A, Compound 33 | US8470820,...)
Affinity DataIC50:  1nMpH: 7.5Assay Description:Scintillation proximity assay using human PDE10A.More data for this Ligand-Target Pair