BDBM98590 (2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-3-hydroxy-propanoyl]amino]-N-[(4-carbamimidoylphenyl)methyl]butanamide::US8476306, 6.16

SMILES CC(OCc1ccccc1)[C@H](NC(=O)[C@@H](CO)NS(=O)(=O)Cc1ccccc1)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=JXDRVTULOVVFJK-KDVIAZGZSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 98590   

TargetSerine protease 1(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98590((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...)
Affinity DataKi:  11nM ΔG°:  -10.8kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against TrypsinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetUrokinase plasminogen activator surface receptor(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98590((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...)
Affinity DataKi:  61nM ΔG°:  -9.80kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against Plasminogen activator urokinaseMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetProthrombin(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98590((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...)
Affinity DataKi:  100nM ΔG°:  -9.51kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against ThrombinMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPlasminogen(Rattus norvegicus)
The Medicines

US Patent
LigandPNGBDBM98590((2S)-3-benzyloxy-2-[[(2R)-2-(benzylsulfonylamino)-...)
Affinity DataKi:  1.10E+3nM ΔG°:  -8.10kcal/moleT: 2°CAssay Description:Inhibition constant of the compound against PlasminMore data for this Ligand-Target Pair
In DepthDetails US Patent