BDBM98607 2-amino-7-(3-cyclopropyl-3-hydroxy-prop-1-ynyl)-1-ethyl-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide::US8470847, 11

SMILES CCn1c(N)c(C(=O)NC)c(=O)c2ccc(nc12)C#CC(O)C1CC1

InChI Key InChIKey=PWJXCRWJUTXVLW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 98607   

TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Sanofi

US Patent
LigandPNGBDBM98607(2-amino-7-(3-cyclopropyl-3-hydroxy-prop-1-ynyl)-1-...)
Affinity DataIC50:  37nMT: 2°CAssay Description:Activity of VEGFR-3 is measured by ELISA assay by measuring the intensity of phosphorylation of the substrate poly Glu-Tyr.More data for this Ligand-Target Pair
In DepthDetails US Patent