BDBM99352 US8497281, 130::US9120769, 63::US9663470, 63

SMILES Nc1cc(ccc1F)C(=O)N1CCCC2[C@@H]1CCc1ccccc21

InChI Key InChIKey=NINJZUNQYYUQPJ-CVMIBEPCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 99352   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM99352(US8497281, 130 | US9120769, 63 | US9663470, 63)
Affinity DataIC50:  1.34E+3nMpH: 6.0 T: 2°CAssay Description:In vitro inhibition of 11beta-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluoresence) technology (cisbio international...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM99352(US8497281, 130 | US9120769, 63 | US9663470, 63)
Affinity DataIC50:  1.34E+3nMAssay Description:In vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internatio...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM99352(US8497281, 130 | US9120769, 63 | US9663470, 63)
Affinity DataIC50:  1.34E+3nMpH: 6.0Assay Description:n vitro inhibition of 11β-HSD1 by test compounds is determined with HTRF (Homogeneous Time-Resolved Fluorescence) technology (cisbio internation...More data for this Ligand-Target Pair
In DepthDetails US Patent