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Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 332.3
BDBM50431942
Wt: 347.4
BDBM50431947
Wt: 679.8
BDBM50122449

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 24 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)


(Homo sapiens (Human))
BDBM50122449
PNG
(CHEMBL3622483)
Show SMILES CCN(C(=O)c1ccc(CNc2nc(NCCN3CCN(C)CC3)nc(n2)N2CCc3cc(OC)c(OC)cc3C2)cc1)c1cccc(C)c1
Show InChI InChI=1S/C38H49N9O3/c1-6-47(32-9-7-8-27(2)22-32)35(48)29-12-10-28(11-13-29)25-40-37-41-36(39-15-17-45-20-18-44(3)19-21-45)42-38(43-37)46-16-14-30-23-33(49-4)34(50-5)24-31(30)26-46/h7-13,22-24H,6,14-21,25-26H2,1-5H3,(H2,39,40,41,42,43)
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n/an/a 10n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of recombinant human ADAMTS4 (213 to 575 amino acid residues) using WAAG-3R as substrate preincubated for 15 mins followed by substrate ad...


ACS Med Chem Lett 6: 888-93 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00138
BindingDB Entry DOI: 10.7270/Q2416ZWQ
More data for this
Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)


(Homo sapiens (Human))
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a 230n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assay


Eur J Med Chem 71: 250-8 (2014)


Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15
More data for this
Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)


(Homo sapiens (Human))
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a 230n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET method


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)


(Homo sapiens (Human))
BDBM50431942
PNG
(CHEMBL2347847)
Show SMILES OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccc1
Show InChI InChI=1S/C15H12N2O3S2/c18-11-8-21-12(16-11)7-13-17-15(9-4-2-1-3-5-9)10(22-13)6-14(19)20/h1-5,7H,6,8H2,(H,16,18)(H,19,20)/b12-7+
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n/an/a 1.20E+3n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET method


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)


(Homo sapiens (Human))
BDBM50122449
PNG
(CHEMBL3622483)
Show SMILES CCN(C(=O)c1ccc(CNc2nc(NCCN3CCN(C)CC3)nc(n2)N2CCc3cc(OC)c(OC)cc3C2)cc1)c1cccc(C)c1
Show InChI InChI=1S/C38H49N9O3/c1-6-47(32-9-7-8-27(2)22-32)35(48)29-12-10-28(11-13-29)25-40-37-41-36(39-15-17-45-20-18-44(3)19-21-45)42-38(43-37)46-16-14-30-23-33(49-4)34(50-5)24-31(30)26-46/h7-13,22-24H,6,14-21,25-26H2,1-5H3,(H2,39,40,41,42,43)
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of ADAMTS5 (unknown origin) using WAAG-3R as substrate preincubated for 15 mins followed by substrate addition measured every 30 secs for ...


ACS Med Chem Lett 6: 888-93 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00138
BindingDB Entry DOI: 10.7270/Q2416ZWQ
More data for this
Ligand-Target Pair
ADAM17


(Homo sapiens (Human))
BDBM50122449
PNG
(CHEMBL3622483)
Show SMILES CCN(C(=O)c1ccc(CNc2nc(NCCN3CCN(C)CC3)nc(n2)N2CCc3cc(OC)c(OC)cc3C2)cc1)c1cccc(C)c1
Show InChI InChI=1S/C38H49N9O3/c1-6-47(32-9-7-8-27(2)22-32)35(48)29-12-10-28(11-13-29)25-40-37-41-36(39-15-17-45-20-18-44(3)19-21-45)42-38(43-37)46-16-14-30-23-33(49-4)34(50-5)24-31(30)26-46/h7-13,22-24H,6,14-21,25-26H2,1-5H3,(H2,39,40,41,42,43)
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human recombinant TACE using Mca-PLAQAV-Dpa-RSSSR-NH2 as substrate preincubated for 15 mins measured every 30 secs for 30 mins by fluor...


ACS Med Chem Lett 6: 888-93 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00138
BindingDB Entry DOI: 10.7270/Q2416ZWQ
More data for this
Ligand-Target Pair
Collagenase


(Homo sapiens (human))
BDBM50122449
PNG
(CHEMBL3622483)
Show SMILES CCN(C(=O)c1ccc(CNc2nc(NCCN3CCN(C)CC3)nc(n2)N2CCc3cc(OC)c(OC)cc3C2)cc1)c1cccc(C)c1
Show InChI InChI=1S/C38H49N9O3/c1-6-47(32-9-7-8-27(2)22-32)35(48)29-12-10-28(11-13-29)25-40-37-41-36(39-15-17-45-20-18-44(3)19-21-45)42-38(43-37)46-16-14-30-23-33(49-4)34(50-5)24-31(30)26-46/h7-13,22-24H,6,14-21,25-26H2,1-5H3,(H2,39,40,41,42,43)
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP13 using 5-FAMTPGPLGL[Dap(DNP)]ARRK(5-TAMRA)-amide as substrate after 45 mins


ACS Med Chem Lett 6: 888-93 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00138
BindingDB Entry DOI: 10.7270/Q2416ZWQ
More data for this
Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 13


(Homo sapiens)
BDBM50122449
PNG
(CHEMBL3622483)
Show SMILES CCN(C(=O)c1ccc(CNc2nc(NCCN3CCN(C)CC3)nc(n2)N2CCc3cc(OC)c(OC)cc3C2)cc1)c1cccc(C)c1
Show InChI InChI=1S/C38H49N9O3/c1-6-47(32-9-7-8-27(2)22-32)35(48)29-12-10-28(11-13-29)25-40-37-41-36(39-15-17-45-20-18-44(3)19-21-45)42-38(43-37)46-16-14-30-23-33(49-4)34(50-5)24-31(30)26-46/h7-13,22-24H,6,14-21,25-26H2,1-5H3,(H2,39,40,41,42,43)
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n/an/a>1.00E+4n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ADAMTS13 using FRETSVWF73 as substrate by fluorescence assay


ACS Med Chem Lett 6: 888-93 (2015)


Article DOI: 10.1021/acsmedchemlett.5b00138
BindingDB Entry DOI: 10.7270/Q2416ZWQ
More data for this
Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)


(Homo sapiens (Human))
BDBM50431942
PNG
(CHEMBL2347847)
Show SMILES OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccc1
Show InChI InChI=1S/C15H12N2O3S2/c18-11-8-21-12(16-11)7-13-17-15(9-4-2-1-3-5-9)10(22-13)6-14(19)20/h1-5,7H,6,8H2,(H,16,18)(H,19,20)/b12-7+
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n/an/a>1.00E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of ADAMTS-4 (unknown origin) by FRET method


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 13


(Homo sapiens)
BDBM50431942
PNG
(CHEMBL2347847)
Show SMILES OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccc1
Show InChI InChI=1S/C15H12N2O3S2/c18-11-8-21-12(16-11)7-13-17-15(9-4-2-1-3-5-9)10(22-13)6-14(19)20/h1-5,7H,6,8H2,(H,16,18)(H,19,20)/b12-7+
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n/an/a 1.20E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of ADAMTS-13 (unknown origin)


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
ADAM17


(Homo sapiens (Human))
BDBM50431942
PNG
(CHEMBL2347847)
Show SMILES OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccc1
Show InChI InChI=1S/C15H12N2O3S2/c18-11-8-21-12(16-11)7-13-17-15(9-4-2-1-3-5-9)10(22-13)6-14(19)20/h1-5,7H,6,8H2,(H,16,18)(H,19,20)/b12-7+
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n/an/a 1.60E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of TACE (unknown origin)


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 13


(Homo sapiens)
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a 2.00E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of ADAMTS-13 (unknown origin)


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
ADAMTS5


(Bos taurus)
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a 2.20E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Ex vivo inhibition of ADAMTS-5-mediated aggrecan degradation in IL-1-stimulated bovine cartilage explant


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)


(Homo sapiens (Human))
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a 2.30E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ADAMTS-4 using interglobular domain peptide of aggrecan after 60 mins by FRET assay


Eur J Med Chem 71: 250-8 (2014)


Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15
More data for this
Ligand-Target Pair
A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)


(Homo sapiens (Human))
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a 2.30E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of ADAMTS-4 (unknown origin) by FRET method


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
Matrix metalloproteinase-14 (MMP14)


(Homo sapiens (Human))
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a 2.40E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of MMP14 (unknown origin) by FRET method


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
Matrix metalloproteinase-14 (MMP14)


(Homo sapiens (Human))
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a 2.40E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MMP-14 using fluorescence peptide matrix as substrate after 45 mins by fluorescence plate reader analysis


Eur J Med Chem 71: 250-8 (2014)


Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15
More data for this
Ligand-Target Pair
Collagenase


(homo sapiens (human))
BDBM50431942
PNG
(CHEMBL2347847)
Show SMILES OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccc1
Show InChI InChI=1S/C15H12N2O3S2/c18-11-8-21-12(16-11)7-13-17-15(9-4-2-1-3-5-9)10(22-13)6-14(19)20/h1-5,7H,6,8H2,(H,16,18)(H,19,20)/b12-7+
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n/an/a>3.00E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of MMP2 (unknown origin) by FRET method


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
Collagenase


(homo sapiens (human))
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a>3.00E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of MMP2 (unknown origin) by FRET method


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
Stromelysin-1


(Homo sapiens (human))
BDBM50431942
PNG
(CHEMBL2347847)
Show SMILES OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccc1
Show InChI InChI=1S/C15H12N2O3S2/c18-11-8-21-12(16-11)7-13-17-15(9-4-2-1-3-5-9)10(22-13)6-14(19)20/h1-5,7H,6,8H2,(H,16,18)(H,19,20)/b12-7+
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n/an/a>3.00E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of MMP3 (unknown origin) by FRET method


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
Stromelysin-1


(Homo sapiens (human))
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a>3.00E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of MMP3 (unknown origin) by FRET method


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
Matrix metalloproteinase-14 (MMP14)


(Homo sapiens (Human))
BDBM50431942
PNG
(CHEMBL2347847)
Show SMILES OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccc1
Show InChI InChI=1S/C15H12N2O3S2/c18-11-8-21-12(16-11)7-13-17-15(9-4-2-1-3-5-9)10(22-13)6-14(19)20/h1-5,7H,6,8H2,(H,16,18)(H,19,20)/b12-7+
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n/an/a>3.00E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of MMP14 (unknown origin) by FRET method


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
ADAM17


(Homo sapiens (Human))
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a>3.00E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of TACE (unknown origin)


Bioorg Med Chem Lett 23: 2106-10 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.121
BindingDB Entry DOI: 10.7270/Q26974ZF
More data for this
Ligand-Target Pair
ADAM17


(Homo sapiens (Human))
BDBM50431947
PNG
(CHEMBL2348091)
Show SMILES OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1
Show InChI InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+
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n/an/a>3.00E+4n/an/an/an/an/an/a



Asahi Kasei Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of TACE (unknown origin)


Eur J Med Chem 71: 250-8 (2014)


Article DOI: 10.1016/j.ejmech.2013.10.075
BindingDB Entry DOI: 10.7270/Q2F76F15
More data for this
Ligand-Target Pair