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Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 366.2
BDBM48721
Purchase
Wt: 401.2
BDBM50440527
Wt: 383.3
BDBM50440531
Purchase
Wt: 340.3
BDBM50440533
Wt: 388.4
BDBM50440538

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 27 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bloom syndrome protein


(Homo sapiens)
BDBM50440527
PNG
(CHEMBL2426164)
Show SMILES Brc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N
Show InChI InChI=1S/C15H9BrN6OS/c16-12-2-1-11(7-10(12)8-17)19-14(23)20-15-22-21-13(24-15)9-3-5-18-6-4-9/h1-7H,(H2,19,20,22,23)
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n/an/a 110n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
Bloom syndrome protein


(Homo sapiens)
BDBM50440533
PNG
(CHEMBL2426169)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N
Show InChI InChI=1S/C15H9FN6OS/c16-12-2-1-11(7-10(12)8-17)19-14(23)20-15-22-21-13(24-15)9-3-5-18-6-4-9/h1-7H,(H2,19,20,22,23)
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n/an/a 300n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
Bloom syndrome protein


(Homo sapiens)
BDBM50440538
PNG
(CHEMBL2426174)
Show SMILES O=C(Nc1nnc(s1)-c1ccncc1)Nc1ccc(-c2cn[nH]c2)c(c1)C#N
Show InChI InChI=1S/C18H12N8OS/c19-8-12-7-14(1-2-15(12)13-9-21-22-10-13)23-17(27)24-18-26-25-16(28-18)11-3-5-20-6-4-11/h1-7,9-10H,(H,21,22)(H2,23,24,26,27)
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n/an/a 1.10E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
Werner syndrome ATP-dependent helicase


(Homo sapiens)
BDBM50440527
PNG
(CHEMBL2426164)
Show SMILES Brc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N
Show InChI InChI=1S/C15H9BrN6OS/c16-12-2-1-11(7-10(12)8-17)19-14(23)20-15-22-21-13(24-15)9-3-5-18-6-4-9/h1-7H,(H2,19,20,22,23)
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n/an/a 1.10E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
DNA (cytosine-5)-methyltransferase 1 (DNMT1)


(Homo sapiens (Human))
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a 1.29E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2NC5ZRN
More data for this
Ligand-Target Pair
Bloom syndrome protein


(Homo sapiens)
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a 1.40E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
Dual specificity protein phosphatase (VHR)


(Homo sapiens (human))
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a 1.56E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q29G5K79
More data for this
Ligand-Target Pair
Bloom syndrome protein


(Homo sapiens)
BDBM50440531
PNG
(CHEMBL2426168)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C(F)(F)F
Show InChI InChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)
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n/an/a 1.80E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of BLM (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
Werner syndrome ATP-dependent helicase


(Homo sapiens)
BDBM50440533
PNG
(CHEMBL2426169)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N
Show InChI InChI=1S/C15H9FN6OS/c16-12-2-1-11(7-10(12)8-17)19-14(23)20-15-22-21-13(24-15)9-3-5-18-6-4-9/h1-7H,(H2,19,20,22,23)
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n/an/a 2.20E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
BZLF2


(Human herpesvirus 4 type 2)
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a 2.45E+3n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Theodore Jardetzky; Northw...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q2057DCW
More data for this
Ligand-Target Pair
Werner syndrome ATP-dependent helicase


(Homo sapiens)
BDBM50440531
PNG
(CHEMBL2426168)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C(F)(F)F
Show InChI InChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)
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n/an/a 2.70E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
Bloom syndrome protein


(Homo sapiens)
BDBM50440531
PNG
(CHEMBL2426168)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C(F)(F)F
Show InChI InChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)
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n/an/a 3.00E+3n/an/an/an/an/an/a



Drexel University College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of BLM helicase (unknown origin) binding to DNA


Bioorg Med Chem Lett 24: 3006-13 (2014)


Article DOI: 10.1016/j.bmcl.2014.04.088
BindingDB Entry DOI: 10.7270/Q2NV9KW7
More data for this
Ligand-Target Pair
Werner syndrome ATP-dependent helicase


(Homo sapiens)
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a 3.40E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
Werner syndrome ATP-dependent helicase


(Homo sapiens)
BDBM50440531
PNG
(CHEMBL2426168)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C(F)(F)F
Show InChI InChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)
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n/an/a 5.00E+3n/an/an/an/an/an/a



Drexel University College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of WRN helicase (unknown origin)


Bioorg Med Chem Lett 24: 3006-13 (2014)


Article DOI: 10.1016/j.bmcl.2014.04.088
BindingDB Entry DOI: 10.7270/Q2NV9KW7
More data for this
Ligand-Target Pair
Dual specificity protein phosphatase (VHR)


(Homo sapiens (human))
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a 5.30E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2445JXV
More data for this
Ligand-Target Pair
Werner syndrome ATP-dependent helicase


(Homo sapiens)
BDBM50440538
PNG
(CHEMBL2426174)
Show SMILES O=C(Nc1nnc(s1)-c1ccncc1)Nc1ccc(-c2cn[nH]c2)c(c1)C#N
Show InChI InChI=1S/C18H12N8OS/c19-8-12-7-14(1-2-15(12)13-9-21-22-10-13)23-17(27)24-18-26-25-16(28-18)11-3-5-20-6-4-11/h1-7,9-10H,(H,21,22)(H2,23,24,26,27)
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n/an/a 7.10E+3n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of WRN (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
MKP-3


(Rattus norvegicus)
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a 1.62E+4n/an/an/an/an/an/a



Sanford-Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2W66J6B
More data for this
Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (human))
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a 1.87E+4n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer...


PubChem Bioassay (2008)


BindingDB Entry DOI: 10.7270/Q23X8539
More data for this
Ligand-Target Pair
Voltage-gated calcium channel subunit alpha Cav2.2


(Homo sapiens (Human))
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a 2.11E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay


Assay Description
Data Source: Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute Network...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2PZ578V
More data for this
Ligand-Target Pair
core protein


(Hepatitis C virus)
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a>4.98E+4n/an/an/an/an/an/a



The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay


Assay Description
Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q29Z939R
More data for this
Ligand-Target Pair
ATP-dependent DNA helicase Q1


(Homo sapiens)
BDBM50440538
PNG
(CHEMBL2426174)
Show SMILES O=C(Nc1nnc(s1)-c1ccncc1)Nc1ccc(-c2cn[nH]c2)c(c1)C#N
Show InChI InChI=1S/C18H12N8OS/c19-8-12-7-14(1-2-15(12)13-9-21-22-10-13)23-17(27)24-18-26-25-16(28-18)11-3-5-20-6-4-11/h1-7,9-10H,(H,21,22)(H2,23,24,26,27)
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n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
ATP-dependent DNA helicase Q1


(Homo sapiens)
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
Bloom syndrome protein


(Homo sapiens)
BDBM50440531
PNG
(CHEMBL2426168)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C(F)(F)F
Show InChI InChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Drexel University College of Medicine

Curated by ChEMBL


Assay Description
Inhibition of BLM helicase (unknown origin) assessed as branch migration activity


Bioorg Med Chem Lett 24: 3006-13 (2014)


Article DOI: 10.1016/j.bmcl.2014.04.088
BindingDB Entry DOI: 10.7270/Q2NV9KW7
More data for this
Ligand-Target Pair
ATP-dependent DNA helicase Q1


(Homo sapiens)
BDBM50440527
PNG
(CHEMBL2426164)
Show SMILES Brc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N
Show InChI InChI=1S/C15H9BrN6OS/c16-12-2-1-11(7-10(12)8-17)19-14(23)20-15-22-21-13(24-15)9-3-5-18-6-4-9/h1-7H,(H2,19,20,22,23)
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n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
ATP-dependent DNA helicase Q1


(Homo sapiens)
BDBM50440531
PNG
(CHEMBL2426168)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C(F)(F)F
Show InChI InChI=1S/C15H9F4N5OS/c16-11-2-1-9(7-10(11)15(17,18)19)21-13(25)22-14-24-23-12(26-14)8-3-5-20-6-4-8/h1-7H,(H2,21,22,24,25)
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n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
ATP-dependent DNA helicase Q1


(Homo sapiens)
BDBM50440533
PNG
(CHEMBL2426169)
Show SMILES Fc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1C#N
Show InChI InChI=1S/C15H9FN6OS/c16-12-2-1-11(7-10(12)8-17)19-14(23)20-15-22-21-13(24-15)9-3-5-18-6-4-9/h1-7H,(H2,19,20,22,23)
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n/an/a>5.00E+4n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of RECQ1 (unknown origin) by gel-based DNA unwinding assay


Bioorg Med Chem Lett 23: 5660-6 (2013)

Checked by Author
Article DOI: 10.1016/j.bmcl.2013.08.025
BindingDB Entry DOI: 10.7270/Q2KK9D78
More data for this
Ligand-Target Pair
eukaryotic translation initiation factor 4 gamma, 1 isoform 4


(Homo sapiens)
BDBM48721
PNG
(1-(3,4-Dichloro-phenyl)-3-(5-pyridin-4-yl-[1,3,4]t...)
Show SMILES Clc1ccc(NC(=O)Nc2nnc(s2)-c2ccncc2)cc1Cl
Show InChI InChI=1S/C14H9Cl2N5OS/c15-10-2-1-9(7-11(10)16)18-13(22)19-14-21-20-12(23-14)8-3-5-17-6-4-8/h1-7H,(H2,18,19,21,22)
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n/an/a 6.40E+4n/an/an/an/an/an/a



Emory University Molecular Libraries Screening Center

Curated by PubChem BioAssay


Assay Description
Dose Response Confirmation for Small Molecule Inhibitors of Eukaryotic Translation Initiation NIH Molecular Libraries Screening Centers Network [MLSC...


PubChem Bioassay (2009)


BindingDB Entry DOI: 10.7270/Q2RN3686
More data for this
Ligand-Target Pair