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Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 296.8
BDBM50227903
Wt: 296.4
BDBM50227914
Wt: 344.4
BDBM50227902
Wt: 364.8
BDBM50227937
Wt: 352.4
BDBM50227911
Wt: 310.4
BDBM50227915
Wt: 282.8
BDBM50227913
Wt: 358.4
BDBM50227918
Wt: 350.8
BDBM50227916
Wt: 364.9
BDBM50227919
Wt: 276.4
BDBM50227922
Wt: 385.7
BDBM50227906
Wt: 262.3
BDBM50227924
Wt: 384.3
BDBM50227932
Wt: 356.5
BDBM50227933
Displayed 1 to 15 (of 119 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 29 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227933
PNG
(CHEMBL77761)
Show SMILES CCCCCCCN(Cc1ccco1)C(=O)Nc1cc(C)c(C)cc1C
Show InChI InChI=1S/C22H32N2O2/c1-5-6-7-8-9-12-24(16-20-11-10-13-26-20)22(25)23-21-15-18(3)17(2)14-19(21)4/h10-11,13-15H,5-9,12,16H2,1-4H3,(H,23,25)
KEGG

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n/an/a 140n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Muscarinic acetylcholine receptor derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227918
PNG
(CHEMBL75224)
Show SMILES Cc1cc(C)c(NC(=O)N(Cc2ccccc2)Cc2ccccc2)cc1C
Show InChI InChI=1S/C24H26N2O/c1-18-14-20(3)23(15-19(18)2)25-24(27)26(16-21-10-6-4-7-11-21)17-22-12-8-5-9-13-22/h4-15H,16-17H2,1-3H3,(H,25,27)
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n/an/a 446n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227918
PNG
(CHEMBL75224)
Show SMILES Cc1cc(C)c(NC(=O)N(Cc2ccccc2)Cc2ccccc2)cc1C
Show InChI InChI=1S/C24H26N2O/c1-18-14-20(3)23(15-19(18)2)25-24(27)26(16-21-10-6-4-7-11-21)17-22-12-8-5-9-13-22/h4-15H,16-17H2,1-3H3,(H,25,27)
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n/an/a 1.08E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against ACAT derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227902
PNG
(CHEMBL76706)
Show SMILES Cc1ccc(NC(=O)N(Cc2ccccc2)Cc2ccccc2)c(C)c1
Show InChI InChI=1S/C23H24N2O/c1-18-13-14-22(19(2)15-18)24-23(26)25(16-20-9-5-3-6-10-20)17-21-11-7-4-8-12-21/h3-15H,16-17H2,1-2H3,(H,24,26)
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n/an/a 1.71E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227915
PNG
(CHEMBL421876)
Show SMILES CCCCN(Cc1ccccc1)C(=O)Nc1ccc(C)cc1C
Show InChI InChI=1S/C20H26N2O/c1-4-5-13-22(15-18-9-7-6-8-10-18)20(23)21-19-12-11-16(2)14-17(19)3/h6-12,14H,4-5,13,15H2,1-3H3,(H,21,23)
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n/an/a 1.83E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227933
PNG
(CHEMBL77761)
Show SMILES CCCCCCCN(Cc1ccco1)C(=O)Nc1cc(C)c(C)cc1C
Show InChI InChI=1S/C22H32N2O2/c1-5-6-7-8-9-12-24(16-20-11-10-13-26-20)22(25)23-21-15-18(3)17(2)14-19(21)4/h10-11,13-15H,5-9,12,16H2,1-4H3,(H,23,25)
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n/an/a 2.24E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Muscarinic acetylcholine receptor derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227932
PNG
(CHEMBL77164)
Show SMILES FC(F)(F)c1cccc(NC(=O)N(Cc2ccccc2)Cc2ccccc2)c1
Show InChI InChI=1S/C22H19F3N2O/c23-22(24,25)19-12-7-13-20(14-19)26-21(28)27(15-17-8-3-1-4-9-17)16-18-10-5-2-6-11-18/h1-14H,15-16H2,(H,26,28)
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n/an/a 2.86E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227937
PNG
(CHEMBL76258)
Show SMILES Cc1ccc(NC(=O)N(Cc2ccccc2)Cc2ccccc2)cc1Cl
Show InChI InChI=1S/C22H21ClN2O/c1-17-12-13-20(14-21(17)23)24-22(26)25(15-18-8-4-2-5-9-18)16-19-10-6-3-7-11-19/h2-14H,15-16H2,1H3,(H,24,26)
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n/an/a 3.01E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227906
PNG
(CHEMBL74091)
Show SMILES CCCCN(Cc1ccccc1)C(=O)Nc1c(Cl)cc(Cl)cc1Cl
Show InChI InChI=1S/C18H19Cl3N2O/c1-2-3-9-23(12-13-7-5-4-6-8-13)18(24)22-17-15(20)10-14(19)11-16(17)21/h4-8,10-11H,2-3,9,12H2,1H3,(H,22,24)
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n/an/a 3.62E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227902
PNG
(CHEMBL76706)
Show SMILES Cc1ccc(NC(=O)N(Cc2ccccc2)Cc2ccccc2)c(C)c1
Show InChI InChI=1S/C23H24N2O/c1-18-13-14-22(19(2)15-18)24-23(26)25(16-20-9-5-3-6-10-20)17-21-11-7-4-8-12-21/h3-15H,16-17H2,1-2H3,(H,24,26)
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n/an/a 3.77E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227915
PNG
(CHEMBL421876)
Show SMILES CCCCN(Cc1ccccc1)C(=O)Nc1ccc(C)cc1C
Show InChI InChI=1S/C20H26N2O/c1-4-5-13-22(15-18-9-7-6-8-10-18)20(23)21-19-12-11-16(2)14-17(19)3/h6-12,14H,4-5,13,15H2,1-3H3,(H,21,23)
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n/an/a 4.83E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227924
PNG
(CHEMBL307709)
Show SMILES CCCCN(CCCC)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C16H26N2O/c1-4-6-11-18(12-7-5-2)16(19)17-15-10-8-9-14(3)13-15/h8-10,13H,4-7,11-12H2,1-3H3,(H,17,19)
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n/an/a 4.95E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227919
PNG
(CHEMBL76200)
Show SMILES Cc1c(Cl)cccc1NC(=O)N(CCC(C)(C)C)Cc1cccs1
Show InChI InChI=1S/C19H25ClN2OS/c1-14-16(20)8-5-9-17(14)21-18(23)22(11-10-19(2,3)4)13-15-7-6-12-24-15/h5-9,12H,10-11,13H2,1-4H3,(H,21,23)
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n/an/a 6.30E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227903
PNG
(CHEMBL307722)
Show SMILES CCCCN(CCCC)C(=O)Nc1ccc(C)c(Cl)c1
Show InChI InChI=1S/C16H25ClN2O/c1-4-6-10-19(11-7-5-2)16(20)18-14-9-8-13(3)15(17)12-14/h8-9,12H,4-7,10-11H2,1-3H3,(H,18,20)
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n/an/a 6.40E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227911
PNG
(CHEMBL77343)
Show SMILES CC(C)(C)CCN(Cc1cccs1)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C18H22F2N2OS/c1-18(2,3)8-9-22(12-14-5-4-10-24-14)17(23)21-16-7-6-13(19)11-15(16)20/h4-7,10-11H,8-9,12H2,1-3H3,(H,21,23)
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n/an/a 6.80E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227919
PNG
(CHEMBL76200)
Show SMILES Cc1c(Cl)cccc1NC(=O)N(CCC(C)(C)C)Cc1cccs1
Show InChI InChI=1S/C19H25ClN2OS/c1-14-16(20)8-5-9-17(14)21-18(23)22(11-10-19(2,3)4)13-15-7-6-12-24-15/h5-9,12H,10-11,13H2,1-4H3,(H,21,23)
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n/an/a 6.85E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227916
PNG
(CHEMBL307666)
Show SMILES Clc1cccc(NC(=O)N(Cc2ccccc2)Cc2ccccc2)c1
Show InChI InChI=1S/C21H19ClN2O/c22-19-12-7-13-20(14-19)23-21(25)24(15-17-8-3-1-4-9-17)16-18-10-5-2-6-11-18/h1-14H,15-16H2,(H,23,25)
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n/an/a 7.69E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227913
PNG
(CHEMBL431965)
Show SMILES CCCCN(CCCC)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C15H23ClN2O/c1-3-5-10-18(11-6-4-2)15(19)17-14-9-7-8-13(16)12-14/h7-9,12H,3-6,10-11H2,1-2H3,(H,17,19)
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n/an/a 9.54E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227932
PNG
(CHEMBL77164)
Show SMILES FC(F)(F)c1cccc(NC(=O)N(Cc2ccccc2)Cc2ccccc2)c1
Show InChI InChI=1S/C22H19F3N2O/c23-22(24,25)19-12-7-13-20(14-19)26-21(28)27(15-17-8-3-1-4-9-17)16-18-10-5-2-6-11-18/h1-14H,15-16H2,(H,26,28)
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n/an/a 9.62E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227922
PNG
(CHEMBL73867)
Show SMILES CCCCN(CCCC)C(=O)Nc1ccc(C)cc1C
Show InChI InChI=1S/C17H28N2O/c1-5-7-11-19(12-8-6-2)17(20)18-16-10-9-14(3)13-15(16)4/h9-10,13H,5-8,11-12H2,1-4H3,(H,18,20)
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n/an/a 9.76E+3n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227922
PNG
(CHEMBL73867)
Show SMILES CCCCN(CCCC)C(=O)Nc1ccc(C)cc1C
Show InChI InChI=1S/C17H28N2O/c1-5-7-11-19(12-8-6-2)17(20)18-16-10-9-14(3)13-15(16)4/h9-10,13H,5-8,11-12H2,1-4H3,(H,18,20)
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n/an/a 1.01E+4n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227903
PNG
(CHEMBL307722)
Show SMILES CCCCN(CCCC)C(=O)Nc1ccc(C)c(Cl)c1
Show InChI InChI=1S/C16H25ClN2O/c1-4-6-10-19(11-7-5-2)16(20)18-14-9-8-13(3)15(17)12-14/h8-9,12H,4-7,10-11H2,1-3H3,(H,18,20)
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n/an/a 1.28E+4n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227911
PNG
(CHEMBL77343)
Show SMILES CC(C)(C)CCN(Cc1cccs1)C(=O)Nc1ccc(F)cc1F
Show InChI InChI=1S/C18H22F2N2OS/c1-18(2,3)8-9-22(12-14-5-4-10-24-14)17(23)21-16-7-6-13(19)11-15(16)20/h4-7,10-11H,8-9,12H2,1-3H3,(H,21,23)
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n/an/a 1.70E+4n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227937
PNG
(CHEMBL76258)
Show SMILES Cc1ccc(NC(=O)N(Cc2ccccc2)Cc2ccccc2)cc1Cl
Show InChI InChI=1S/C22H21ClN2O/c1-17-12-13-20(14-21(17)23)24-22(26)25(15-18-8-4-2-5-9-18)16-19-10-6-3-7-11-19/h2-14H,15-16H2,1H3,(H,24,26)
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n/an/a 1.89E+4n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against Acyl coenzyme A:cholesterol acyltransferase derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Sterol O-acyltransferase, Soat


(Rattus norvegicus)
BDBM50227914
PNG
(CHEMBL75012)
Show SMILES CCCCN(C(=O)Nc1ccc(C)cc1C)c1ccccc1
Show InChI InChI=1S/C19H24N2O/c1-4-5-13-21(17-9-7-6-8-10-17)19(22)20-18-12-11-15(2)14-16(18)3/h6-12,14H,4-5,13H2,1-3H3,(H,20,22)
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n/an/a 2.12E+4n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against ACAT derived from rat adrenals


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227924
PNG
(CHEMBL307709)
Show SMILES CCCCN(CCCC)C(=O)Nc1cccc(C)c1
Show InChI InChI=1S/C16H26N2O/c1-4-6-11-18(12-7-5-2)16(19)17-15-10-8-9-14(3)13-15/h8-10,13H,4-7,11-12H2,1-3H3,(H,17,19)
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n/an/a 2.40E+4n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227914
PNG
(CHEMBL75012)
Show SMILES CCCCN(C(=O)Nc1ccc(C)cc1C)c1ccccc1
Show InChI InChI=1S/C19H24N2O/c1-4-5-13-21(17-9-7-6-8-10-17)19(22)20-18-12-11-15(2)14-16(18)3/h6-12,14H,4-5,13H2,1-3H3,(H,20,22)
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n/an/a 2.69E+4n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against ACAT derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227913
PNG
(CHEMBL431965)
Show SMILES CCCCN(CCCC)C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C15H23ClN2O/c1-3-5-10-18(11-6-4-2)15(19)17-14-9-7-8-13(16)12-14/h7-9,12H,3-6,10-11H2,1-2H3,(H,17,19)
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n/an/a 3.21E+4n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair
Acyl coenzyme A:cholesterol acyltransferase 1


(Homo sapiens (human))
BDBM50227916
PNG
(CHEMBL307666)
Show SMILES Clc1cccc(NC(=O)N(Cc2ccccc2)Cc2ccccc2)c1
Show InChI InChI=1S/C21H19ClN2O/c22-19-12-7-13-20(14-19)23-21(25)24(15-17-8-3-1-4-9-17)16-18-10-5-2-6-11-18/h1-14H,15-16H2,(H,23,25)
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n/an/a 3.99E+4n/an/an/an/an/an/a



American Cyanamid Company

Curated by ChEMBL


Assay Description
In vitro inhibitory concentration against acyl coenzyme A:cholesterol acyltransferase derived from smooth muscle cells from thoracic aorta of monkeys


J Med Chem 32: 2318-25 (1989)


Article DOI: 10.1021/jm00130a016
More data for this
Ligand-Target Pair