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Found 10 Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 2 [348-455]'
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205431((6S+2S)-PEG1 (7))
Affinity DataKi:  0.00690nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205453(MTI (35))
Affinity DataKi:  0.0330nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM50452557(CHEMBL4206677 | US11028051, Cmpd 55)
Affinity DataKd:  20nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM50452554(CHEMBL4207106 | US11028051, Cmpd 51)
Affinity DataKd:  300nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM50452552(CHEMBL4205876 | US11028051, Cmpd 52)
Affinity DataKd:  21nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM50452556(CHEMBL4210405 | US11028051, Cmpd 53)
Affinity DataKd:  17nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM50452553(CHEMBL4202664 | US11028051, Cmpd 54)
Affinity DataKd:  36nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205429( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...)
Affinity DataKd:  112nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM205429( (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US10...)
Affinity DataKd:  18nMAssay Description:Refer to DiscoverXMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBromodomain-containing protein 2 [348-455](Homo sapiens (Human))
Dana-Farber Cancer Institute

LigandPNGBDBM50452551(CHEMBL4209110 | US11028051, Cmpd 50)
Affinity DataKd:  280nMAssay Description:Binding of compounds to BRD2 was monitored using an ITC200 (Microcal, Piscataway, N.J.). Either Brd2.1 (74-194) or Brd2.2 (348-455) was dialyzed over...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent