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Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 89.0
BDBM23222
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Wt: 169.1
BDBM93321
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Wt: 145.1
BDBM93322
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Wt: 143.1
BDBM93294
Wt: 145.1
BDBM93295
Wt: 183.1
BDBM93297
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Wt: 147.1
BDBM93303
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Wt: 173.2
BDBM93305
Wt: 179.1
BDBM93306
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Wt: 161.1
BDBM93307
Wt: 173.2
BDBM93310
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Wt: 145.1
BDBM93313
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Wt: 171.1
BDBM93315
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Wt: 159.1
BDBM93316
Wt: 173.1
BDBM93317
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Displayed 1 to 15 (of 37 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 46 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lactate dehydrogenase A (LDHA)


(Homo sapiens (Human))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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2.60E+4n/an/an/an/an/an/an/an/a



ARIAD Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human LDH-A


J Med Chem 56: 1023-40 (2013)


Article DOI: 10.1021/jm3014844
BindingDB Entry DOI: 10.7270/Q2QC04TB
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lactate dehydrogenase B (LDHB)


(Homo sapiens (human))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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9.44E+4n/an/an/an/an/an/an/an/a



National Cancer Institute-CRO

Curated by ChEMBL


Assay Description
Competitive inhibition of human LDH1 in presence of NADH


J Med Chem 59: 487-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b00168
BindingDB Entry DOI: 10.7270/Q2B27X41
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
L-lactate dehydrogenase A chain


(Homo sapiens (Human))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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1.36E+5n/an/an/an/an/an/an/an/a



National Cancer Institute-CRO

Curated by ChEMBL


Assay Description
Competitive inhibition of human LDH5 in presence of NADH


J Med Chem 59: 487-96 (2016)


Article DOI: 10.1021/acs.jmedchem.5b00168
BindingDB Entry DOI: 10.7270/Q2B27X41
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lactate dehydrogenase A (LDHA)


(Homo sapiens (Human))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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1.38E+5n/an/an/an/an/an/an/an/a



Universita` di Pisa

Curated by ChEMBL


Assay Description
Inhibition of human LDH-A using pyruvate as substrate and NADH as cofactor at 125 uM after 5 mins by calorimetric assay relative to control


J Med Chem 54: 1599-612 (2011)


Article DOI: 10.1021/jm101007q
BindingDB Entry DOI: 10.7270/Q2J38SVC
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93303
PNG
(Oxamic Acid/Ester, 21)
Show SMILES COCCNC(=O)C(O)=O
Show InChI InChI=1S/C5H9NO4/c1-10-3-2-6-4(7)5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9)
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n/an/a 1.40E+4n/an/an/an/an/an/a



University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93303
PNG
(Oxamic Acid/Ester, 21)
Show SMILES COCCNC(=O)C(O)=O
Show InChI InChI=1S/C5H9NO4/c1-10-3-2-6-4(7)5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9)
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n/an/a 2.50E+4n/an/an/an/an/an/a



University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
L-lactate:NAD+ oxidoreductase C (LDH-C4)


(Mus musculus (Mouse))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 3.00E+4n/an/an/an/a7.4n/a



Instituto Politécnico Nacional



Assay Description
Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...


J Enzyme Inhib Med Chem 26: 579-86 (2011)


Article DOI: 10.3109/14756366.2011.566221
BindingDB Entry DOI: 10.7270/Q2R78D36
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93307
PNG
(Oxamic Acid/Ester, 25)
Show SMILES COCCCNC(=O)C(O)=O
Show InChI InChI=1S/C6H11NO4/c1-11-4-2-3-7-5(8)6(9)10/h2-4H2,1H3,(H,7,8)(H,9,10)
UniProtKB/TrEMBL

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n/an/a 3.10E+4n/an/an/an/an/an/a



University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase B (LDHB)


(Homo sapiens (human))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 3.38E+4n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHB (1 to 333) expressed in insect cells using pyruvate as substrate after 10 mins by UV...


Bioorg Med Chem Lett 23: 3186-94 (2013)


Article DOI: 10.1016/j.bmcl.2013.04.001
BindingDB Entry DOI: 10.7270/Q29C6ZTT
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lactate dehydrogenase B (LDHB)


(Homo sapiens (human))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 3.38E+4n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assay


Bioorg Med Chem Lett 24: 3764-71 (2014)


Article DOI: 10.1016/j.bmcl.2014.06.076
BindingDB Entry DOI: 10.7270/Q2445P46
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93307
PNG
(Oxamic Acid/Ester, 25)
Show SMILES COCCCNC(=O)C(O)=O
Show InChI InChI=1S/C6H11NO4/c1-11-4-2-3-7-5(8)6(9)10/h2-4H2,1H3,(H,7,8)(H,9,10)
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n/an/a 4.30E+4n/an/an/an/an/an/a



University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93315
PNG
(Oxamic Acid/Ester, 33)
Show SMILES CC1CCCCN1C(=O)C(O)=O
Show InChI InChI=1S/C8H13NO3/c1-6-4-2-3-5-9(6)7(10)8(11)12/h6H,2-5H2,1H3,(H,11,12)
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n/an/a 4.30E+4n/an/an/an/an/an/a



University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93305
PNG
(Oxamic Acid/Ester, 23)
Show SMILES CCCCCCNC(=O)C(O)=O
Show InChI InChI=1S/C8H15NO3/c1-2-3-4-5-6-9-7(10)8(11)12/h2-6H2,1H3,(H,9,10)(H,11,12)
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n/an/a 4.70E+4n/an/an/an/an/an/a



University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase A (LDHA)


(Homo sapiens (Human))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 5.72E+4n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carboxy-terminal His-tagged LDHA by UV endpoint assay


Bioorg Med Chem Lett 24: 3764-71 (2014)


Article DOI: 10.1016/j.bmcl.2014.06.076
BindingDB Entry DOI: 10.7270/Q2445P46
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lactate dehydrogenase A (LDHA)


(Homo sapiens (Human))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 5.72E+4n/an/an/an/an/an/a



Genentech

Curated by ChEMBL


Assay Description
Inhibition of human recombinant carboxy-terminal his-tagged LDHA (1 to 331) expressed in Escherichia coli using pyruvate as substrate after 10 mins b...


Bioorg Med Chem Lett 23: 3186-94 (2013)


Article DOI: 10.1016/j.bmcl.2013.04.001
BindingDB Entry DOI: 10.7270/Q29C6ZTT
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
L-lactate:NAD+ oxidoreductase B (LDH-B4)


(Mus musculus (Mouse))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 6.00E+4n/an/an/an/a7.4n/a



Instituto Politécnico Nacional



Assay Description
Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...


J Enzyme Inhib Med Chem 26: 579-86 (2011)


Article DOI: 10.3109/14756366.2011.566221
BindingDB Entry DOI: 10.7270/Q2R78D36
More data for this
Ligand-Target Pair
L-lactate:NAD+ oxidoreductase A (LDH-A4)


(Mus musculus (Mouse))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 8.00E+4n/an/an/an/a7.4n/a



Instituto Politécnico Nacional



Assay Description
Lactate dehydrogenase activity was determined by recording the absorbance change at 340 nm produced by the oxidation of NADH. Assays were performed a...


J Enzyme Inhib Med Chem 26: 579-86 (2011)


Article DOI: 10.3109/14756366.2011.566221
BindingDB Entry DOI: 10.7270/Q2R78D36
More data for this
Ligand-Target Pair
Lactate Dehydrogenase


(Plasmodium falciparum)
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 9.25E+4n/an/an/an/a7.025



University of Mississippi



Assay Description
LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...


J Med Chem 50: 3841-50 (2007)


Article DOI: 10.1021/jm070336k
BindingDB Entry DOI: 10.7270/Q2HH6HCV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 9.44E+4n/an/an/an/an/an/a



University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 1.16E+5n/an/an/an/an/an/a



University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate Dehydrogenase


(Bos taurus (bovine))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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n/an/a 1.23E+5n/an/an/an/a7.025



University of Mississippi



Assay Description
LDH was assayed spectrophotometrically for reduction of pyruvate using NADH by recording the changed in absorbance at 340 nm. The reaction was initia...


J Med Chem 50: 3841-50 (2007)


Article DOI: 10.1021/jm070336k
BindingDB Entry DOI: 10.7270/Q2HH6HCV
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93305
PNG
(Oxamic Acid/Ester, 23)
Show SMILES CCCCCCNC(=O)C(O)=O
Show InChI InChI=1S/C8H15NO3/c1-2-3-4-5-6-9-7(10)8(11)12/h2-6H2,1H3,(H,9,10)(H,11,12)
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n/an/a 1.33E+5n/an/an/an/an/an/a



University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93316
PNG
(Oxamic Acid/Ester, 34)
Show SMILES CC(C)CCNC(=O)C(O)=O
Show InChI InChI=1S/C7H13NO3/c1-5(2)3-4-8-6(9)7(10)11/h5H,3-4H2,1-2H3,(H,8,9)(H,10,11)
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n/an/a 1.57E+5n/an/an/an/an/an/a



University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93317
PNG
(Oxamic Acid/Ester, 35)
Show SMILES OC(=O)C(=O)NCC1CCCO1
Show InChI InChI=1S/C7H11NO4/c9-6(7(10)11)8-4-5-2-1-3-12-5/h5H,1-4H2,(H,8,9)(H,10,11)
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University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93321
PNG
(Oxamic Acid/Ester, 39)
Show SMILES OC(=O)C(=O)NCc1ccco1
Show InChI InChI=1S/C7H7NO4/c9-6(7(10)11)8-4-5-2-1-3-12-5/h1-3H,4H2,(H,8,9)(H,10,11)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93306
PNG
(Oxamic Acid/Ester, 24)
Show SMILES CN(C(=O)C(O)=O)c1ccccc1
Show InChI InChI=1S/C9H9NO3/c1-10(8(11)9(12)13)7-5-3-2-4-6-7/h2-6H,1H3,(H,12,13)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93310
PNG
(Oxamic Acid/Ester, 28)
Show SMILES CCCCCN(C)C(=O)C(O)=O
Show InChI InChI=1S/C8H15NO3/c1-3-4-5-6-9(2)7(10)8(11)12/h3-6H2,1-2H3,(H,11,12)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93313
PNG
(Oxamic Acid/Ester, 31)
Show SMILES CCC(C)NC(=O)C(O)=O
Show InChI InChI=1S/C6H11NO3/c1-3-4(2)7-5(8)6(9)10/h4H,3H2,1-2H3,(H,7,8)(H,9,10)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93316
PNG
(Oxamic Acid/Ester, 34)
Show SMILES CC(C)CCNC(=O)C(O)=O
Show InChI InChI=1S/C7H13NO3/c1-5(2)3-4-8-6(9)7(10)11/h5H,3-4H2,1-2H3,(H,8,9)(H,10,11)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93317
PNG
(Oxamic Acid/Ester, 35)
Show SMILES OC(=O)C(=O)NCC1CCCO1
Show InChI InChI=1S/C7H11NO4/c9-6(7(10)11)8-4-5-2-1-3-12-5/h5H,1-4H2,(H,8,9)(H,10,11)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93321
PNG
(Oxamic Acid/Ester, 39)
Show SMILES OC(=O)C(=O)NCc1ccco1
Show InChI InChI=1S/C7H7NO4/c9-6(7(10)11)8-4-5-2-1-3-12-5/h1-3H,4H2,(H,8,9)(H,10,11)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93322
PNG
(Oxamic Acid/Ester, 40)
Show SMILES CC(C)CNC(=O)C(O)=O
Show InChI InChI=1S/C6H11NO3/c1-4(2)3-7-5(8)6(9)10/h4H,3H2,1-2H3,(H,7,8)(H,9,10)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93315
PNG
(Oxamic Acid/Ester, 33)
Show SMILES CC1CCCCN1C(=O)C(O)=O
Show InChI InChI=1S/C8H13NO3/c1-6-4-2-3-5-9(6)7(10)8(11)12/h6H,2-5H2,1H3,(H,11,12)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93313
PNG
(Oxamic Acid/Ester, 31)
Show SMILES CCC(C)NC(=O)C(O)=O
Show InChI InChI=1S/C6H11NO3/c1-3-4(2)7-5(8)6(9)10/h4H,3H2,1-2H3,(H,7,8)(H,9,10)
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University of Mississippi



Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93310
PNG
(Oxamic Acid/Ester, 28)
Show SMILES CCCCCN(C)C(=O)C(O)=O
Show InChI InChI=1S/C8H15NO3/c1-3-4-5-6-9(2)7(10)8(11)12/h3-6H2,1-2H3,(H,11,12)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93306
PNG
(Oxamic Acid/Ester, 24)
Show SMILES CN(C(=O)C(O)=O)c1ccccc1
Show InChI InChI=1S/C9H9NO3/c1-10(8(11)9(12)13)7-5-3-2-4-6-7/h2-6H,1H3,(H,12,13)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93297
PNG
(Oxamic Acid/Ester, 15)
Show SMILES Cc1ccc(CNC(=O)C(O)=O)o1
Show InChI InChI=1S/C8H9NO4/c1-5-2-3-6(13-5)4-9-7(10)8(11)12/h2-3H,4H2,1H3,(H,9,10)(H,11,12)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93295
PNG
(Oxamic Acid/Ester, 12)
Show SMILES CCCCNC(=O)C(O)=O
Show InChI InChI=1S/C6H11NO3/c1-2-3-4-7-5(8)6(9)10/h2-4H2,1H3,(H,7,8)(H,9,10)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93294
PNG
(Oxamic Acid/Ester, 11)
Show SMILES CN(CC=C)C(=O)C(O)=O
Show InChI InChI=1S/C6H9NO3/c1-3-4-7(2)5(8)6(9)10/h3H,1,4H2,2H3,(H,9,10)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93297
PNG
(Oxamic Acid/Ester, 15)
Show SMILES Cc1ccc(CNC(=O)C(O)=O)o1
Show InChI InChI=1S/C8H9NO4/c1-5-2-3-6(13-5)4-9-7(10)8(11)12/h2-3H,4H2,1H3,(H,9,10)(H,11,12)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Plasmodium falciparum)
BDBM93322
PNG
(Oxamic Acid/Ester, 40)
Show SMILES CC(C)CNC(=O)C(O)=O
Show InChI InChI=1S/C6H11NO3/c1-4(2)3-7-5(8)6(9)10/h4H,3H2,1-2H3,(H,7,8)(H,9,10)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93294
PNG
(Oxamic Acid/Ester, 11)
Show SMILES CN(CC=C)C(=O)C(O)=O
Show InChI InChI=1S/C6H9NO3/c1-3-4-7(2)5(8)6(9)10/h3H,1,4H2,2H3,(H,9,10)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Lactate dehydrogenase (LDH)


(Bos taurus (Bovine))
BDBM93295
PNG
(Oxamic Acid/Ester, 12)
Show SMILES CCCCNC(=O)C(O)=O
Show InChI InChI=1S/C6H11NO3/c1-2-3-4-7-5(8)6(9)10/h2-4H2,1H3,(H,7,8)(H,9,10)
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Assay Description
Enzyme assay using recombinant pfLDH and mLDH (bovine heart).


J Comb Chem 9: 292-300


Article DOI: 10.1021/cc060110n
BindingDB Entry DOI: 10.7270/Q23J3BKZ
More data for this
Ligand-Target Pair
Malate Dehydrogenase, mitochondrial


(Sus scrofa (pig))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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University of Mississippi



Assay Description
MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...


J Med Chem 50: 3841-50 (2007)


Article DOI: 10.1021/jm070336k
BindingDB Entry DOI: 10.7270/Q2HH6HCV
More data for this
Ligand-Target Pair
Malate Dehydrogenase (pfMDH)


(Plasmodium falciparum)
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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University of Mississippi



Assay Description
MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...


J Med Chem 50: 3841-50 (2007)


Article DOI: 10.1021/jm070336k
BindingDB Entry DOI: 10.7270/Q2HH6HCV
More data for this
Ligand-Target Pair
Malate dehydrogenase cytoplasmic


(Sus scrofa (pig))
BDBM23222
PNG
(Oxalamic acid | Oxamate | Oxamate, 3 | Oxamidic Ac...)
Show SMILES NC(=O)C(O)=O
Show InChI InChI=1S/C2H3NO3/c3-1(4)2(5)6/h(H2,3,4)(H,5,6)
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University of Mississippi



Assay Description
MDH was assayed spectrophotometrically for reduction of oxaloacetic acid using NADH by recording the changed in absorbance at 340 nm. The reaction wa...


J Med Chem 50: 3841-50 (2007)


Article DOI: 10.1021/jm070336k
BindingDB Entry DOI: 10.7270/Q2HH6HCV
More data for this
Ligand-Target Pair