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Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 125.0
BDBM50017377
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Wt: 148.2
BDBM50022743
Wt: 147.2
BDBM50022745
Wt: 133.2
BDBM50022748
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Wt: 117.1
BDBM50022749
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Wt: 131.2
BDBM50022753
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Wt: 87.1
BDBM50024589
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Wt: 111.0
BDBM50024591
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Wt: 152.1
BDBM50024593
Wt: 167.1
BDBM50024594
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Wt: 167.1
BDBM50024597
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Wt: 153.1
BDBM50024602
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Wt: 139.0
BDBM50024604
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Wt: 149.1
BDBM50078132
Wt: 115.1
BDBM50129685
Displayed 1 to 15 (of 83 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 37 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Leucine aminopeptidase (LAP)


(Sus scrofa (Pig))
BDBM50024594
PNG
((R)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)
Show SMILES CC(C)C[C@H]([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m1/s1
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0.230n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of pig recombinant leucine aminopeptidase after 30 to 60 mins by morrison's equation


J Med Chem 57: 8140-51 (2014)


Article DOI: 10.1021/jm501071f
BindingDB Entry DOI: 10.7270/Q2CF9RQF
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022743
PNG
(2,6-Diamino-hexane-1-thiol | CHEMBL68509)
Show SMILES NCCCC[C@@H](N)CS
Show InChI InChI=1S/C6H16N2S/c7-4-2-1-3-6(8)5-9/h6,9H,1-5,7-8H2/t6-/m1/s1
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0.910n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens)
BDBM50024594
PNG
((R)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)
Show SMILES CC(C)C[C@H]([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m1/s1
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2.60n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation


J Med Chem 57: 8140-51 (2014)


Article DOI: 10.1021/jm501071f
BindingDB Entry DOI: 10.7270/Q2CF9RQF
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50022748
PNG
(2-Amino-4-methyl-pentane-1-thiol | CHEMBL69349)
Show SMILES CC(C)C[C@@H](N)CS
Show InChI InChI=1S/C6H15NS/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m1/s1
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20n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Aminopeptidase M


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50024594
PNG
((R)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)
Show SMILES CC(C)C[C@H]([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m1/s1
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53n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of pig recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation


J Med Chem 57: 8140-51 (2014)


Article DOI: 10.1021/jm501071f
BindingDB Entry DOI: 10.7270/Q2CF9RQF
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50129685
PNG
(2-Amino-4-methyl-pentanal | CHEMBL88476)
Show SMILES CC(C)CC(N)C=O
Show InChI InChI=1S/C6H13NO/c1-5(2)3-6(7)4-8/h4-6H,3,7H2,1-2H3
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60n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney


J Med Chem 46: 2641-55 (2003)


Article DOI: 10.1021/jm030795v
BindingDB Entry DOI: 10.7270/Q27P903F
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50022743
PNG
(2,6-Diamino-hexane-1-thiol | CHEMBL68509)
Show SMILES NCCCC[C@@H](N)CS
Show InChI InChI=1S/C6H16N2S/c7-4-2-1-3-6(8)5-9/h6,9H,1-5,7-8H2/t6-/m1/s1
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110n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Aminopeptidase M


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022748
PNG
(2-Amino-4-methyl-pentane-1-thiol | CHEMBL69349)
Show SMILES CC(C)C[C@@H](N)CS
Show InChI InChI=1S/C6H15NS/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m1/s1
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130n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens)
BDBM50024597
PNG
((S)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)
Show SMILES CC(C)C[C@@H]([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m0/s1
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167n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of human recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation


J Med Chem 57: 8140-51 (2014)


Article DOI: 10.1021/jm501071f
BindingDB Entry DOI: 10.7270/Q2CF9RQF
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50024597
PNG
((S)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)
Show SMILES CC(C)C[C@@H]([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m0/s1
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192n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of pig recombinant alanyl aminopeptidase after 30 to 60 mins by morrison's equation


J Med Chem 57: 8140-51 (2014)


Article DOI: 10.1021/jm501071f
BindingDB Entry DOI: 10.7270/Q2CF9RQF
More data for this
Ligand-Target Pair
Leucine aminopeptidase (LAP)


(Sus scrofa (Pig))
BDBM50024597
PNG
((S)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)
Show SMILES CC(C)C[C@@H]([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m0/s1
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220n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of pig recombinant leucine aminopeptidase after 30 to 60 mins by morrison's equation


J Med Chem 57: 8140-51 (2014)


Article DOI: 10.1021/jm501071f
BindingDB Entry DOI: 10.7270/Q2CF9RQF
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50024594
PNG
((R)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)
Show SMILES CC(C)C[C@H]([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m1/s1
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230n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Leucine aminopeptidase isolated from porcine kidney.


J Med Chem 30: 1603-9 (1987)


Article DOI: 10.1021/jm00392a014
BindingDB Entry DOI: 10.7270/Q2W66MCD
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50024602
PNG
(1-Ammonium-2-methyl-propane-1-phosphonic acid anio...)
Show SMILES CC(C)C([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C4H12NO3P/c1-3(2)4(5)9(6,7)8/h3-4H,5H2,1-2H3,(H2,6,7,8)
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1.20E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of Leucine aminopeptidase isolated from porcine kidney; Inhibitor exhibits slow-binding behavior(k on <=1000Me-1Se...


J Med Chem 30: 1603-9 (1987)


Article DOI: 10.1021/jm00392a014
BindingDB Entry DOI: 10.7270/Q2W66MCD
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50078132
PNG
((1-Amino-3-methyl-butyl)-phosphinic acid | (1-Ammo...)
Show SMILES CC(C)CC(=N)P(O)O
Show InChI InChI=1S/C5H12NO2P/c1-4(2)3-5(6)9(7)8/h4,6-8H,3H2,1-2H3
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1.20E+3n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N


Bioorg Med Chem Lett 9: 1511-6 (1999)


Article DOI: 10.1016/s0960-894x(99)00236-x
BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50024604
PNG
(1-Ammonium-propane-1-phosphonic acid anion | 1-ami...)
Show SMILES CCC([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C3H10NO3P/c1-2-3(4)8(5,6)7/h3H,2,4H2,1H3,(H2,5,6,7)
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3.60E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of Leucine aminopeptidase isolated from porcine kidney; Inhibitor exhibits slow-binding behavior(k on <=1000Me-1Se...


J Med Chem 30: 1603-9 (1987)


Article DOI: 10.1021/jm00392a014
BindingDB Entry DOI: 10.7270/Q2W66MCD
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50022745
PNG
(3-Amino-5-methyl-hexane-2-thiol | CHEMBL69814)
Show SMILES CC(C)C[C@H](N)C(C)S
Show InChI InChI=1S/C7H17NS/c1-5(2)4-7(8)6(3)9/h5-7,9H,4,8H2,1-3H3/t6?,7-/m0/s1
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6.00E+3n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Aminopeptidase M


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022745
PNG
(3-Amino-5-methyl-hexane-2-thiol | CHEMBL69814)
Show SMILES CC(C)C[C@H](N)C(C)S
Show InChI InChI=1S/C7H17NS/c1-5(2)4-7(8)6(3)9/h5-7,9H,4,8H2,1-3H3/t6?,7-/m0/s1
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7.00E+3n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50024597
PNG
((S)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)
Show SMILES CC(C)C[C@@H]([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m0/s1
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5.30E+4n/an/an/an/an/an/an/an/a



Trinity College

Curated by ChEMBL


Assay Description
Inhibition of pig kidney microsomal aminopeptidase N


Antimicrob Agents Chemother 52: 3221-8 (2008)


Article DOI: 10.1128/AAC.01327-07
BindingDB Entry DOI: 10.7270/Q2S75GMX
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50078132
PNG
((1-Amino-3-methyl-butyl)-phosphinic acid | (1-Ammo...)
Show SMILES CC(C)CC(=N)P(O)O
Show InChI InChI=1S/C5H12NO2P/c1-4(2)3-5(6)9(7)8/h4,6-8H,3H2,1-2H3
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8.70E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Leucine aminopeptidase isolated from porcine kidney.


J Med Chem 30: 1603-9 (1987)


Article DOI: 10.1021/jm00392a014
BindingDB Entry DOI: 10.7270/Q2W66MCD
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022753
PNG
(3-Amino-5-methyl-hexan-2-ol | CHEMBL68511)
Show SMILES CC(C)C[C@H](N)C(C)O
Show InChI InChI=1S/C7H17NO/c1-5(2)4-7(8)6(3)9/h5-7,9H,4,8H2,1-3H3/t6?,7-/m0/s1
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>2.00E+5n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50024597
PNG
((S)-1-Ammonium-3-methyl-butane-1-phosphonic acid a...)
Show SMILES CC(C)C[C@@H]([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C5H14NO3P/c1-4(2)3-5(6)10(7,8)9/h4-5H,3,6H2,1-2H3,(H2,7,8,9)/t5-/m0/s1
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2.20E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Leucine aminopeptidase isolated from porcine kidney.


J Med Chem 30: 1603-9 (1987)


Article DOI: 10.1021/jm00392a014
BindingDB Entry DOI: 10.7270/Q2W66MCD
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50017377
PNG
((1-Amino-ethyl)-phosphonic acid | 1-Ammonium-ethan...)
Show SMILES CC(N)P(O)(O)=O
Show InChI InChI=1S/C2H8NO3P/c1-2(3)7(4,5)6/h2H,3H2,1H3,(H2,4,5,6)
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2.40E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Leucine aminopeptidase isolated from porcine kidney.


J Med Chem 30: 1603-9 (1987)


Article DOI: 10.1021/jm00392a014
BindingDB Entry DOI: 10.7270/Q2W66MCD
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50022753
PNG
(3-Amino-5-methyl-hexan-2-ol | CHEMBL68511)
Show SMILES CC(C)C[C@H](N)C(C)O
Show InChI InChI=1S/C7H17NO/c1-5(2)4-7(8)6(3)9/h5-7,9H,4,8H2,1-3H3/t6?,7-/m0/s1
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3.55E+5n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Aminopeptidase M


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50022748
PNG
(2-Amino-4-methyl-pentane-1-thiol | CHEMBL69349)
Show SMILES CC(C)C[C@@H](N)CS
Show InChI InChI=1S/C6H15NS/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m1/s1
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4.50E+5n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Leucine aminopeptidase


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50022745
PNG
(3-Amino-5-methyl-hexane-2-thiol | CHEMBL69814)
Show SMILES CC(C)C[C@H](N)C(C)S
Show InChI InChI=1S/C7H17NS/c1-5(2)4-7(8)6(3)9/h5-7,9H,4,8H2,1-3H3/t6?,7-/m0/s1
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>5.00E+5n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Leucine aminopeptidase


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50022753
PNG
(3-Amino-5-methyl-hexan-2-ol | CHEMBL68511)
Show SMILES CC(C)C[C@H](N)C(C)O
Show InChI InChI=1S/C7H17NO/c1-5(2)4-7(8)6(3)9/h5-7,9H,4,8H2,1-3H3/t6?,7-/m0/s1
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5.07E+5n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Leucine aminopeptidase


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50024593
PNG
((3-Methyl-butyl)-phosphonic acid | CHEMBL41600)
Show SMILES CC(C)CCP(O)(O)=O
Show InChI InChI=1S/C5H13O3P/c1-5(2)3-4-9(6,7)8/h5H,3-4H2,1-2H3,(H2,6,7,8)
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7.75E+5n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Leucine aminopeptidase isolated from porcine kidney.


J Med Chem 30: 1603-9 (1987)


Article DOI: 10.1021/jm00392a014
BindingDB Entry DOI: 10.7270/Q2W66MCD
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50022749
PNG
(2-Amino-4-methyl-pentan-1-ol | CHEMBL71171 | D-Leu...)
Show SMILES CC(C)C[C@@H](N)CO
Show InChI InChI=1S/C6H15NO/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m1/s1
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>1.00E+6n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Aminopeptidase M


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50022749
PNG
(2-Amino-4-methyl-pentan-1-ol | CHEMBL71171 | D-Leu...)
Show SMILES CC(C)C[C@@H](N)CO
Show InChI InChI=1S/C6H15NO/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m1/s1
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>1.00E+6n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Leucine aminopeptidase


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022749
PNG
(2-Amino-4-methyl-pentan-1-ol | CHEMBL71171 | D-Leu...)
Show SMILES CC(C)C[C@@H](N)CO
Show InChI InChI=1S/C6H15NO/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m1/s1
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>1.00E+6n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50022743
PNG
(2,6-Diamino-hexane-1-thiol | CHEMBL68509)
Show SMILES NCCCC[C@@H](N)CS
Show InChI InChI=1S/C6H16N2S/c7-4-2-1-3-6(8)5-9/h6,9H,1-5,7-8H2/t6-/m1/s1
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>1.00E+6n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against Leucine aminopeptidase


J Med Chem 31: 2193-9 (1988)


Article DOI: 10.1021/jm00119a022
BindingDB Entry DOI: 10.7270/Q2Z038RM
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50024591
PNG
(Ammonium-methanephosphonic acid anion | CHEMBL4187...)
Show SMILES [NH3+]CP(O)([O-])=O
Show InChI InChI=1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)
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1.04E+6n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Leucine aminopeptidase isolated from porcine kidney.


J Med Chem 30: 1603-9 (1987)


Article DOI: 10.1021/jm00392a014
BindingDB Entry DOI: 10.7270/Q2W66MCD
More data for this
Ligand-Target Pair
Leucine aminopeptidase


(Homo sapiens)
BDBM50024589
PNG
(3-METHYLBUTAN-1-AMINE | 3-Methyl-butylamine | CHEM...)
Show SMILES CC(C)CCN
Show InChI InChI=1S/C5H13N/c1-5(2)3-4-6/h5H,3-4,6H2,1-2H3
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>5.00E+7n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of Leucine aminopeptidase isolated from porcine kidney.


J Med Chem 30: 1603-9 (1987)


Article DOI: 10.1021/jm00392a014
BindingDB Entry DOI: 10.7270/Q2W66MCD
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50017377
PNG
((1-Amino-ethyl)-phosphonic acid | 1-Ammonium-ethan...)
Show SMILES CC(N)P(O)(O)=O
Show InChI InChI=1S/C2H8NO3P/c1-2(3)7(4,5)6/h2H,3H2,1H3,(H2,4,5,6)
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n/an/a 4.20E+4n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50024604
PNG
(1-Ammonium-propane-1-phosphonic acid anion | 1-ami...)
Show SMILES CCC([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C3H10NO3P/c1-2-3(4)8(5,6)7/h3H,2,4H2,1H3,(H2,5,6,7)
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n/an/a 5.00E+4n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50024602
PNG
(1-Ammonium-2-methyl-propane-1-phosphonic acid anio...)
Show SMILES CC(C)C([NH3+])P(O)([O-])=O
Show InChI InChI=1S/C4H12NO3P/c1-3(2)4(5)9(6,7)8/h3-4H,5H2,1-2H3,(H2,6,7,8)
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n/an/a 1.04E+5n/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney aminopeptidase N using Leu-AMC as substrate


Bioorg Med Chem 18: 2930-6 (2010)


Article DOI: 10.1016/j.bmc.2010.02.056
BindingDB Entry DOI: 10.7270/Q2FN16C0
More data for this
Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase


(Staphylococcus epidermidis (strain ATCC 35984 / RP...)
BDBM50017377
PNG
((1-Amino-ethyl)-phosphonic acid | 1-Ammonium-ethan...)
Show SMILES CC(N)P(O)(O)=O
Show InChI InChI=1S/C2H8NO3P/c1-2(3)7(4,5)6/h2H,3H2,1H3,(H2,4,5,6)
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n/an/a 9.30E+5n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Antibacterial activity against D-alanyl-D-alanine ligase from Streptococcus faecalis (ATCC 8043)


J Med Chem 31: 1772-8 (1988)


Article DOI: 10.1021/jm00117a017
BindingDB Entry DOI: 10.7270/Q24B31XZ
More data for this
Ligand-Target Pair