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Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 151.2
BDBM50033369
Purchase
Wt: 151.2
BDBM50343541
Wt: 165.2
BDBM50343542
Wt: 193.2
BDBM50343543
Wt: 165.2
BDBM50343544
Wt: 151.2
BDBM50343545
Wt: 165.2
BDBM50343546
Wt: 153.2
BDBM50343547
Wt: 167.2
BDBM50343548
Wt: 197.2
BDBM50343549
Wt: 197.7
BDBM50020750
Wt: 199.7
BDBM50020752
Wt: 209.7
BDBM50020754
Wt: 161.2
BDBM50079999
Wt: 203.2
BDBM50080000
Displayed 1 to 15 (of 28 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 34 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(HUMAN)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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20n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards sigma receptor in guinea pig brain membrane was determined by using [3H]DTG as the radioligand


Bioorg Med Chem Lett 6: 595-600 (1996)


Article DOI: 10.1016/0960-894X(96)00067-4
BindingDB Entry DOI: 10.7270/Q2GM87TV
More data for this
Ligand-Target Pair
Glutamate-NMDA


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Merz Co. GmbH & Co.

Curated by PDSP Ki Database




Neuropharmacology 34: 533-40 (1995)


BindingDB Entry DOI: 10.7270/Q2M9075F
More data for this
Ligand-Target Pair
Glutamate-NMDA


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Merz Co. GmbH & Co.

Curated by PDSP Ki Database




Neuropharmacology 34: 533-40 (1995)


BindingDB Entry DOI: 10.7270/Q2M9075F
More data for this
Ligand-Target Pair
Glutamate-NMDA


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Merz Co. GmbH & Co.

Curated by PDSP Ki Database




Neuropharmacology 34: 533-40 (1995)


BindingDB Entry DOI: 10.7270/Q2M9075F
More data for this
Ligand-Target Pair
Glutamate-NMDA


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Merz Co. GmbH & Co.

Curated by PDSP Ki Database




Neuropharmacology 34: 533-40 (1995)


BindingDB Entry DOI: 10.7270/Q2M9075F
More data for this
Ligand-Target Pair
Glutamate-NMDA


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Merz Co. GmbH & Co.

Curated by PDSP Ki Database




Neuropharmacology 34: 533-40 (1995)


BindingDB Entry DOI: 10.7270/Q2M9075F
More data for this
Ligand-Target Pair
Glutamate-NMDA


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Merz Co. GmbH & Co.

Curated by PDSP Ki Database




Neuropharmacology 34: 533-40 (1995)


BindingDB Entry DOI: 10.7270/Q2M9075F
More data for this
Ligand-Target Pair
Glutamate-NMDA


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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>1.00E+4n/an/an/an/an/an/an/an/a



Merz Co. GmbH & Co.

Curated by PDSP Ki Database




Neuropharmacology 34: 533-40 (1995)


BindingDB Entry DOI: 10.7270/Q2M9075F
More data for this
Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1


(Homo sapiens)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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1.00E+4n/an/an/an/an/an/an/an/a



Institut f£r Pharmazeutische und Medizinische Chemie der Westf£lischen Wilhelms-Universit£t M£nster

Curated by ChEMBL


Assay Description
Displacement of [3H]-(+)-MK-801 from phencyclidine binding site of NMDA receptor in human frontal cortex after 22 hrs by scintillation counting analy...


Bioorg Med Chem 23: 4277-85 (2015)


Article DOI: 10.1016/j.bmc.2015.06.030
BindingDB Entry DOI: 10.7270/Q29Z96NG
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50080000
PNG
(CHEMBL3415952)
Show SMILES NC(=N)N1C[C@H]2[C@@H](C1)[C@H]1[C@@H]3C4CC1[C@H]2[C@H]34
Show InChI InChI=1S/C12H17N3/c13-12(14)15-2-6-7(3-15)9-4-1-5-10(8(4)6)11(5)9/h4-11H,1-3H2,(H3,13,14)/t4?,5?,6-,7+,8+,9-,10+,11-
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n/an/a 800n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...


Eur J Med Chem 96: 318-29 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.030
BindingDB Entry DOI: 10.7270/Q2B27X1P
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50343543
PNG
(CHEMBL499125 | N-(Hexahydro-2,5-methano-pentalen-3...)
Show SMILES NC(N)=NCC12CC3CC1CC(C2)C3
Show InChI InChI=1S/C11H19N3/c12-10(13)14-6-11-4-7-1-8(5-11)3-9(11)2-7/h7-9H,1-6H2,(H4,12,13,14)
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n/an/a 2.40E+3n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus (A/Udorn/72) wild type matrix protein 2 expressed in xenopus oocytes after 2 mins by two-electrode voltage clamp assa...


J Med Chem 54: 2646-57 (2011)


Article DOI: 10.1021/jm101334y
BindingDB Entry DOI: 10.7270/Q2H41RR0
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus (A/Udorn/307/1972(H3N2)))
BDBM50020750
PNG
(CHEMBL3286970)
Show SMILES C1C2C1C1C=CC2C2CNCC12
Show InChI InChI=1S/C11H15N.ClH/c1-2-7-9-3-8(9)6(1)10-4-12-5-11(7)10;/h1-2,6-12H,3-5H2;1H
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n/an/a 2.92E+3n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of wild type Influenza A virus (A/udorn/72(H3N2)) M2 channel expressed in Xenopus oocyte plasma membrane incubated for 2 mins measured ove...


J Med Chem 57: 5738-47 (2014)


Article DOI: 10.1021/jm5005804
BindingDB Entry DOI: 10.7270/Q23N24Z2
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50079999
PNG
(CHEMBL3415951)
Show SMILES C1NC[C@@H]2[C@H]1[C@@H]1[C@H]3C4CC1[C@@H]2[C@@H]34
Show InChI InChI=1S/C11H15N/c1-4-8-6-2-12-3-7(6)9(4)11-5(1)10(8)11/h4-12H,1-3H2/t4?,5?,6-,7+,8+,9-,10+,11-
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n/an/a 3.30E+3n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of wild type Influenza A virus (A/udorn/1972(H3N2)) M2 channel expressed in Xenopus oocyte plasma membranes after 2 mins by two-electrode ...


Eur J Med Chem 96: 318-29 (2015)


Article DOI: 10.1016/j.ejmech.2015.04.030
BindingDB Entry DOI: 10.7270/Q2B27X1P
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus (A/Udorn/307/1972(H3N2)))
BDBM50020752
PNG
(CHEMBL3286972)
Show SMILES C1C2C1C1CCC2C2CNCC12
Show InChI InChI=1S/C11H17N.ClH/c1-2-7-9-3-8(9)6(1)10-4-12-5-11(7)10;/h6-12H,1-5H2;1H
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n/an/a 3.38E+3n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of wild type Influenza A virus (A/udorn/72(H3N2)) M2 channel expressed in Xenopus oocyte plasma membrane incubated for 2 mins measured ove...


J Med Chem 57: 5738-47 (2014)


Article DOI: 10.1021/jm5005804
BindingDB Entry DOI: 10.7270/Q23N24Z2
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus (A/Udorn/307/1972(H3N2)))
BDBM50020754
PNG
(CHEMBL3286976)
Show SMILES C1NCC2C1C1C=CC2C2C=CC12
Show InChI InChI=1S/C12H15N.ClH/c1-2-8-7(1)9-3-4-10(8)12-6-13-5-11(9)12;/h1-4,7-13H,5-6H2;1H
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n/an/a 5.54E+3n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of wild type Influenza A virus (A/udorn/72(H3N2)) M2 channel expressed in Xenopus oocyte plasma membrane incubated for 2 mins measured ove...


J Med Chem 57: 5738-47 (2014)


Article DOI: 10.1021/jm5005804
BindingDB Entry DOI: 10.7270/Q23N24Z2
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50343541
PNG
(C-(Hexahydro-2,5-methano-pentalen-3a-yl)-methylami...)
Show SMILES NCC12CC3CC1CC(C2)C3
Show InChI InChI=1S/C10H17N/c11-6-10-4-7-1-8(5-10)3-9(10)2-7/h7-9H,1-6,11H2
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n/an/a 7.10E+3n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus (A/Udorn/72) wild type matrix protein 2 expressed in xenopus oocytes after 2 mins by two-electrode voltage clamp assa...


J Med Chem 54: 2646-57 (2011)


Article DOI: 10.1021/jm101334y
BindingDB Entry DOI: 10.7270/Q2H41RR0
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50343546
PNG
(C-(2,5-Dimethyl-hexahydro-2,5-cyclo-pentalen-3a-yl...)
Show SMILES CC12CC3CC1(C)CC3(CN)C2
Show InChI InChI=1S/C11H19N/c1-9-3-8-4-10(9,2)6-11(8,5-9)7-12/h8H,3-7,12H2,1-2H3
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n/an/a 7.20E+3n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus (A/Udorn/72) wild type matrix protein 2 expressed in xenopus oocytes after 2 mins by two-electrode voltage clamp assa...


J Med Chem 54: 2646-57 (2011)


Article DOI: 10.1021/jm101334y
BindingDB Entry DOI: 10.7270/Q2H41RR0
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50343544
PNG
(CHEMBL1774313 | rac-1-(Hexahydro-2,5-methano-penta...)
Show SMILES CC(N)C12CC3CC1CC(C2)C3
Show InChI InChI=1S/C11H19N/c1-7(12)11-5-8-2-9(6-11)4-10(11)3-8/h7-10H,2-6,12H2,1H3
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n/an/a 1.27E+4n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus (A/Udorn/72) wild type matrix protein 2 expressed in xenopus oocytes after 2 mins by two-electrode voltage clamp assa...


J Med Chem 54: 2646-57 (2011)


Article DOI: 10.1021/jm101334y
BindingDB Entry DOI: 10.7270/Q2H41RR0
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus (A/Udorn/307/1972(H3N2)))
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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n/an/a 1.60E+4n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of wild type Influenza A virus (A/udorn/72(H3N2)) M2 channel expressed in Xenopus oocyte plasma membrane incubated for 2 mins measured ove...


J Med Chem 57: 5738-47 (2014)


Article DOI: 10.1021/jm5005804
BindingDB Entry DOI: 10.7270/Q23N24Z2
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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n/an/a 1.60E+4n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus (A/Udorn/72) wild type matrix protein 2 expressed in xenopus oocytes after 2 mins by two-electrode voltage clamp assa...


J Med Chem 54: 2646-57 (2011)


Article DOI: 10.1021/jm101334y
BindingDB Entry DOI: 10.7270/Q2H41RR0
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50343545
PNG
(2,5-Dimethyl-hexahydro-2,5-cyclo-pentalen-3a-ylami...)
Show SMILES CC12CC3CC1(C)CC3(N)C2
Show InChI InChI=1S/C10H17N/c1-8-3-7-4-9(8,2)6-10(7,11)5-8/h7H,3-6,11H2,1-2H3
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n/an/a 1.70E+4n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus (A/Udorn/72) wild type matrix protein 2 expressed in xenopus oocytes after 2 mins by two-electrode voltage clamp assa...


J Med Chem 54: 2646-57 (2011)


Article DOI: 10.1021/jm101334y
BindingDB Entry DOI: 10.7270/Q2H41RR0
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50343542
PNG
((Hexahydro-2,5-methano-pentalen-3a-ylmethyl)-methy...)
Show SMILES CNCC12CC3CC1CC(C2)C3
Show InChI InChI=1S/C11H19N/c1-12-7-11-5-8-2-9(6-11)4-10(11)3-8/h8-10,12H,2-7H2,1H3
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n/an/a 1.71E+4n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus (A/Udorn/72) wild type matrix protein 2 expressed in xenopus oocytes after 2 mins by two-electrode voltage clamp assa...


J Med Chem 54: 2646-57 (2011)


Article DOI: 10.1021/jm101334y
BindingDB Entry DOI: 10.7270/Q2H41RR0
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50343548
PNG
(CHEMBL468166 | Methyl-(2-oxa-tricyclo[3.3.1.1(3,7)...)
Show SMILES CNC12CC3CC(CC(C3)O1)C2
Show InChI InChI=1S/C10H17NO/c1-11-10-5-7-2-8(6-10)4-9(3-7)12-10/h7-9,11H,2-6H2,1H3
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n/an/a 2.29E+4n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus (A/Udorn/72) wild type matrix protein 2 expressed in xenopus oocytes after 2 mins by two-electrode voltage clamp assa...


J Med Chem 54: 2646-57 (2011)


Article DOI: 10.1021/jm101334y
BindingDB Entry DOI: 10.7270/Q2H41RR0
More data for this
Ligand-Target Pair
Solute carrier family 22 member 2


(Homo sapiens)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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n/an/a 2.30E+4n/an/an/an/an/an/a



Institut f£r Physiologie

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of Dopamine uptake (Dopamine: 200 uM) in Xenopus laevis oocytes


Mol Pharmacol 54: 342-52 (1998)


Article DOI: 10.1124/mol.54.2.342
BindingDB Entry DOI: 10.7270/Q2C82BK9
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50343547
PNG
((2-Oxaadamant-1-yl)amine | 2-Oxa-tricyclo[3.3.1.1(...)
Show SMILES NC12CC3CC(CC(C3)O1)C2
Show InChI InChI=1S/C9H15NO/c10-9-4-6-1-7(5-9)3-8(2-6)11-9/h6-8H,1-5,10H2
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n/an/a 2.92E+4n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus (A/Udorn/72) wild type matrix protein 2 expressed in xenopus oocytes after 2 mins by two-electrode voltage clamp assa...


J Med Chem 54: 2646-57 (2011)


Article DOI: 10.1021/jm101334y
BindingDB Entry DOI: 10.7270/Q2H41RR0
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50343549
PNG
(3-Azahexacyclo[7.6.0.0(1,5).0(5,12).0(6,10).0(11,1...)
Show SMILES C1NCC23C4C=CC5C4C4C(C=CC24)C135
Show InChI InChI=1S/C14H15N/c1-2-8-11-7(1)13-5-15-6-14(8,13)10-4-3-9(13)12(10)11/h1-4,7-12,15H,5-6H2
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n/an/a 3.35E+4n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of influenza A virus wild type M2 proton channel expressed in Xenopus oocytes by two-electrode voltage clamp analysis


ACS Med Chem Lett 5: 831-6 (2014)


Article DOI: 10.1021/ml500108s
BindingDB Entry DOI: 10.7270/Q23X8897
More data for this
Ligand-Target Pair
Matrix protein 2


(Influenza A virus)
BDBM50343549
PNG
(3-Azahexacyclo[7.6.0.0(1,5).0(5,12).0(6,10).0(11,1...)
Show SMILES C1NCC23C4C=CC5C4C4C(C=CC24)C135
Show InChI InChI=1S/C14H15N/c1-2-8-11-7(1)13-5-15-6-14(8,13)10-4-3-9(13)12(10)11/h1-4,7-12,15H,5-6H2
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n/an/a 3.35E+4n/an/an/an/an/an/a



Universitat de Barcelona

Curated by ChEMBL


Assay Description
Inhibition of Influenza A virus (A/Udorn/72) wild type matrix protein 2 expressed in xenopus oocytes after 2 mins by two-electrode voltage clamp assa...


J Med Chem 54: 2646-57 (2011)


Article DOI: 10.1021/jm101334y
BindingDB Entry DOI: 10.7270/Q2H41RR0
More data for this
Ligand-Target Pair
Multidrug and toxin extrusion protein 1


(Homo sapiens)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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n/an/a 3.78E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of human MATE1-mediated ASP+ uptake expressed in HEK293 cells after 1.5 mins by fluorescence assay


J Med Chem 56: 781-95 (2013)


Article DOI: 10.1021/jm301302s
BindingDB Entry DOI: 10.7270/Q2F76DWZ
More data for this
Ligand-Target Pair
Adrenaline alpha1


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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n/an/a 7.63E+4n/an/an/an/an/an/a



Tokyo University of Science

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition pramipexole uptake in rOCT1-injected oocytes


Drug Metab Dispos 33: 495-9 (2005)


Article DOI: 10.1124/dmd.104.002519
BindingDB Entry DOI: 10.7270/Q24B32KW
More data for this
Ligand-Target Pair
Adrenaline alpha2


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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n/an/a 2.10E+5n/an/an/an/an/an/a



University of Manitoba

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of TEA uptake (in the presence of bicarbonate) (TEA: 20 uM) in OCT2-expressing HEK293 cells


J Pharmacol Exp Ther 303: 959-68 (2002)


Article DOI: 10.1124/jpet.102.038885
BindingDB Entry DOI: 10.7270/Q28W3FTB
More data for this
Ligand-Target Pair
Adrenaline alpha2


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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n/an/a 2.71E+5n/an/an/an/an/an/a



Tokyo University of Science

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition pramipexole uptake in rOCT2-injected oocytes


Drug Metab Dispos 33: 495-9 (2005)


Article DOI: 10.1124/dmd.104.002519
BindingDB Entry DOI: 10.7270/Q24B32KW
More data for this
Ligand-Target Pair
Adrenaline alpha1


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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n/an/a 2.80E+5n/an/an/an/an/an/a



University of Manitoba

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of TEA uptake (in the absence of bicarbonate) (TEA: 20 uM) in OCT1-expressing HEK293 cells


J Pharmacol Exp Ther 303: 959-68 (2002)


Article DOI: 10.1124/jpet.102.038885
BindingDB Entry DOI: 10.7270/Q28W3FTB
More data for this
Ligand-Target Pair
Adrenaline alpha2


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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n/an/a 2.90E+5n/an/an/an/an/an/a



University of Manitoba

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of TEA uptake (in the absence of bicarbonate) (TEA: 20 uM) in OCT2-expressing HEK293 cells


J Pharmacol Exp Ther 303: 959-68 (2002)


Article DOI: 10.1124/jpet.102.038885
BindingDB Entry DOI: 10.7270/Q28W3FTB
More data for this
Ligand-Target Pair
Adrenaline alpha1


(RAT)
BDBM50033369
PNG
(AMANTADINE | CHEMBL660 | SYMADINE | SYMMETREL)
Show SMILES NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C10H17N/c11-10-4-7-1-8(5-10)3-9(2-7)6-10/h7-9H,1-6,11H2
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n/an/a 5.00E+5n/an/an/an/an/an/a



University of Manitoba

Curated by ChEMBL


Assay Description
TP_TRANSPORTER: inhibition of TEA uptake (in the presence of bicarbonate) (TEA: 20 uM) in OCT1-expressing HEK293 cells


J Pharmacol Exp Ther 303: 959-68 (2002)


Article DOI: 10.1124/jpet.102.038885
BindingDB Entry DOI: 10.7270/Q28W3FTB
More data for this
Ligand-Target Pair