BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 685.7
BDBM50034910
Wt: 453.5
BDBM50111167
Wt: 325.3
BDBM50111181
Wt: 557.6
BDBM50126393
Wt: 601.7
BDBM50130014
Wt: 713.8
BDBM50131238
Wt: 643.7
BDBM50131239
Wt: 713.8
BDBM50131240
Wt: 710.7
BDBM50131241
Wt: 711.8
BDBM50131242
Wt: 699.8
BDBM50131248
Wt: 721.8
BDBM50131249
Wt: 715.8
BDBM50131254
Wt: 701.7
BDBM50131255
Wt: 714.7
BDBM50131259
Displayed 1 to 15 (of 30 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 122 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50034910
PNG
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
35n/an/an/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of europium labeled NDP-alpha-MSH from human MC1R expressed in HEK293 cells


J Med Chem 49: 4745-61 (2006)


Article DOI: 10.1021/jm060384p
BindingDB Entry DOI: 10.7270/Q29W0F4J
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50034910
PNG
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
37n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131238
PNG
((S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Show SMILES CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C36H47N11O5/c1-2-9-31(48)44-30(18-24-20-40-21-43-24)35(52)47-29(16-22-10-4-3-5-11-22)34(51)45-27(14-8-15-41-36(38)39)33(50)46-28(32(37)49)17-23-19-42-26-13-7-6-12-25(23)26/h3-7,10-13,19-21,27-30,42H,2,8-9,14-18H2,1H3,(H2,37,49)(H,40,43)(H,44,48)(H,45,51)(H,46,50)(H,47,52)(H4,38,39,41)/t27-,28-,29-,30-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
38n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 1 receptor (hMC1R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131240
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES CC(C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C36H47N11O5/c1-21(2)32(49)46-30(17-24-19-40-20-43-24)35(52)47-29(15-22-9-4-3-5-10-22)34(51)44-27(13-8-14-41-36(38)39)33(50)45-28(31(37)48)16-23-18-42-26-12-7-6-11-25(23)26/h3-7,9-12,18-21,27-30,42H,8,13-17H2,1-2H3,(H2,37,48)(H,40,43)(H,44,51)(H,45,50)(H,46,49)(H,47,52)(H4,38,39,41)/t27-,28-,29-,30-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
40n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 1 receptor (hMC1R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50131242
PNG
(CHEMBL329586 | Cyclopropanecarboxylic acid [(S)-1-...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C1CC1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C36H45N11O5/c37-31(48)28(16-23-18-42-26-10-5-4-9-25(23)26)45-33(50)27(11-6-14-41-36(38)39)44-34(51)29(15-21-7-2-1-3-8-21)47-35(52)30(17-24-19-40-20-43-24)46-32(49)22-12-13-22/h1-5,7-10,18-20,22,27-30,42H,6,11-17H2,(H2,37,48)(H,40,43)(H,44,51)(H,45,50)(H,46,49)(H,47,52)(H4,38,39,41)/t27-,28-,29-,30-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
43n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 1 receptor (hMC1R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131248
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES CCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C35H45N11O5/c1-2-30(47)43-29(17-23-19-39-20-42-23)34(51)46-28(15-21-9-4-3-5-10-21)33(50)44-26(13-8-14-40-35(37)38)32(49)45-27(31(36)48)16-22-18-41-25-12-7-6-11-24(22)25/h3-7,9-12,18-20,26-29,41H,2,8,13-17H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,37,38,40)/t26-,27-,28-,29-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
48n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131239
PNG
(2-{(S)-2-[(S)-2-Amino-3-(3H-imidazol-4-yl)-propion...)
Show SMILES N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C32H41N11O4/c33-23(15-21-17-37-18-40-21)29(45)43-27(13-19-7-2-1-3-8-19)31(47)41-25(11-6-12-38-32(35)36)30(46)42-26(28(34)44)14-20-16-39-24-10-5-4-9-22(20)24/h1-5,7-10,16-18,23,25-27,39H,6,11-15,33H2,(H2,34,44)(H,37,40)(H,41,47)(H,42,46)(H,43,45)(H4,35,36,38)/t23-,25-,26-,27-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
51n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human melanocortin 4 receptor (hMC4R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50131259
PNG
(CHEMBL328117 | N-[(S)-1-((S)-1-{(S)-1-[(S)-1-Carba...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H42N12O6/c35-28(47)25(14-20-16-41-23-10-5-4-9-22(20)23)44-30(49)24(11-6-12-40-34(37)38)43-31(50)26(13-19-7-2-1-3-8-19)45-32(51)27(46-33(52)29(36)48)15-21-17-39-18-42-21/h1-5,7-10,16-18,24-27,41H,6,11-15H2,(H2,35,47)(H2,36,48)(H,39,42)(H,43,50)(H,44,49)(H,45,51)(H,46,52)(H4,37,38,40)/t24-,25-,26-,27-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
62n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 1 receptor (hMC1R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50131242
PNG
(CHEMBL329586 | Cyclopropanecarboxylic acid [(S)-1-...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C1CC1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C36H45N11O5/c37-31(48)28(16-23-18-42-26-10-5-4-9-25(23)26)45-33(50)27(11-6-14-41-36(38)39)44-34(51)29(15-21-7-2-1-3-8-21)47-35(52)30(17-24-19-40-20-43-24)46-32(49)22-12-13-22/h1-5,7-10,18-20,22,27-30,42H,6,11-17H2,(H2,37,48)(H,40,43)(H,44,51)(H,45,50)(H,46,49)(H,47,52)(H4,38,39,41)/t27-,28-,29-,30-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
87n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human melanocortin 4 receptor (hMC4R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50131241
PNG
((S)-2-{(S)-2-[(S)-2-(2-Cyano-acetylamino)-3-(3H-im...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CC#N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C35H42N12O5/c36-13-12-30(48)44-29(17-23-19-40-20-43-23)34(52)47-28(15-21-7-2-1-3-8-21)33(51)45-26(11-6-14-41-35(38)39)32(50)46-27(31(37)49)16-22-18-42-25-10-5-4-9-24(22)25/h1-5,7-10,18-20,26-29,42H,6,11-12,14-17H2,(H2,37,49)(H,40,43)(H,44,48)(H,45,51)(H,46,50)(H,47,52)(H4,38,39,41)/t26-,27-,28-,29-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
87n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 1 receptor (hMC1R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50131254
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES COCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C35H45N11O6/c1-52-19-30(47)43-29(16-23-18-39-20-42-23)34(51)46-28(14-21-8-3-2-4-9-21)33(50)44-26(12-7-13-40-35(37)38)32(49)45-27(31(36)48)15-22-17-41-25-11-6-5-10-24(22)25/h2-6,8-11,17-18,20,26-29,41H,7,12-16,19H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,37,38,40)/t26-,27-,28-,29-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
92n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 1 receptor (hMC1R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131240
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES CC(C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C36H47N11O5/c1-21(2)32(49)46-30(17-24-19-40-20-43-24)35(52)47-29(15-22-9-4-3-5-10-22)34(51)44-27(13-8-14-41-36(38)39)33(50)45-28(31(37)48)16-23-18-42-26-12-7-6-11-25(23)26/h3-7,9-12,18-21,27-30,42H,8,13-17H2,1-2H3,(H2,37,48)(H,40,43)(H,44,51)(H,45,50)(H,46,49)(H,47,52)(H4,38,39,41)/t27-,28-,29-,30-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
98n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC1R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50131241
PNG
((S)-2-{(S)-2-[(S)-2-(2-Cyano-acetylamino)-3-(3H-im...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CC#N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C35H42N12O5/c36-13-12-30(48)44-29(17-23-19-40-20-43-23)34(52)47-28(15-21-7-2-1-3-8-21)33(51)45-26(11-6-14-41-35(38)39)32(50)46-27(31(37)49)16-22-18-42-25-10-5-4-9-24(22)25/h1-5,7-10,18-20,26-29,42H,6,11-12,14-17H2,(H2,37,49)(H,40,43)(H,44,48)(H,45,51)(H,46,50)(H,47,52)(H4,38,39,41)/t26-,27-,28-,29-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
110n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human melanocortin 4 receptor (hMC4R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50131255
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-2-(2-hydroxy-acetyla...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H43N11O6/c35-30(48)26(14-21-16-40-24-10-5-4-9-23(21)24)44-31(49)25(11-6-12-39-34(36)37)43-32(50)27(13-20-7-2-1-3-8-20)45-33(51)28(42-29(47)18-46)15-22-17-38-19-41-22/h1-5,7-10,16-17,19,25-28,40,46H,6,11-15,18H2,(H2,35,48)(H,38,41)(H,42,47)(H,43,50)(H,44,49)(H,45,51)(H4,36,37,39)/t25-,26-,27-,28-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
125n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 1 receptor (hMC1R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50131259
PNG
(CHEMBL328117 | N-[(S)-1-((S)-1-{(S)-1-[(S)-1-Carba...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H42N12O6/c35-28(47)25(14-20-16-41-23-10-5-4-9-22(20)23)44-30(49)24(11-6-12-40-34(37)38)43-31(50)26(13-19-7-2-1-3-8-19)45-32(51)27(46-33(52)29(36)48)15-21-17-39-18-42-21/h1-5,7-10,16-18,24-27,41H,6,11-15H2,(H2,35,47)(H2,36,48)(H,39,42)(H,43,50)(H,44,49)(H,45,51)(H,46,52)(H4,37,38,40)/t24-,25-,26-,27-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
140n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human melanocortin 4 receptor (hMC4R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131238
PNG
((S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Show SMILES CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C36H47N11O5/c1-2-9-31(48)44-30(18-24-20-40-21-43-24)35(52)47-29(16-22-10-4-3-5-11-22)34(51)45-27(14-8-15-41-36(38)39)33(50)46-28(32(37)49)17-23-19-42-26-13-7-6-12-25(23)26/h3-7,10-13,19-21,27-30,42H,2,8-9,14-18H2,1H3,(H2,37,49)(H,40,43)(H,44,48)(H,45,51)(H,46,50)(H,47,52)(H4,38,39,41)/t27-,28-,29-,30-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
150n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC1R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131248
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES CCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C35H45N11O5/c1-2-30(47)43-29(17-23-19-39-20-42-23)34(51)46-28(15-21-9-4-3-5-10-21)33(50)44-26(13-8-14-40-35(37)38)32(49)45-27(31(36)48)16-22-18-41-25-12-7-6-11-24(22)25/h3-7,9-12,18-20,26-29,41H,2,8,13-17H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,37,38,40)/t26-,27-,28-,29-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
160n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131259
PNG
(CHEMBL328117 | N-[(S)-1-((S)-1-{(S)-1-[(S)-1-Carba...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C(N)=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H42N12O6/c35-28(47)25(14-20-16-41-23-10-5-4-9-22(20)23)44-30(49)24(11-6-12-40-34(37)38)43-31(50)26(13-19-7-2-1-3-8-19)45-32(51)27(46-33(52)29(36)48)15-21-17-39-18-42-21/h1-5,7-10,16-18,24-27,41H,6,11-15H2,(H2,35,47)(H2,36,48)(H,39,42)(H,43,50)(H,44,49)(H,45,51)(H,46,52)(H4,37,38,40)/t24-,25-,26-,27-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
160n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131249
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES CS(=O)(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C33H43N11O6S/c1-51(49,50)44-28(16-22-18-37-19-40-22)32(48)43-27(14-20-8-3-2-4-9-20)31(47)41-25(12-7-13-38-33(35)36)30(46)42-26(29(34)45)15-21-17-39-24-11-6-5-10-23(21)24/h2-6,8-11,17-19,25-28,39,44H,7,12-16H2,1H3,(H2,34,45)(H,37,40)(H,41,47)(H,42,46)(H,43,48)(H4,35,36,38)/t25-,26-,27-,28-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
170n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC4R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131239
PNG
(2-{(S)-2-[(S)-2-Amino-3-(3H-imidazol-4-yl)-propion...)
Show SMILES N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C32H41N11O4/c33-23(15-21-17-37-18-40-21)29(45)43-27(13-19-7-2-1-3-8-19)31(47)41-25(11-6-12-38-32(35)36)30(46)42-26(28(34)44)14-20-16-39-24-10-5-4-9-22(20)24/h1-5,7-10,16-18,23,25-27,39H,6,11-15,33H2,(H2,34,44)(H,37,40)(H,41,47)(H,42,46)(H,43,45)(H4,35,36,38)/t23-,25-,26-,27-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
180n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131242
PNG
(CHEMBL329586 | Cyclopropanecarboxylic acid [(S)-1-...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)C1CC1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C36H45N11O5/c37-31(48)28(16-23-18-42-26-10-5-4-9-25(23)26)45-33(50)27(11-6-14-41-36(38)39)44-34(51)29(15-21-7-2-1-3-8-21)47-35(52)30(17-24-19-40-20-43-24)46-32(49)22-12-13-22/h1-5,7-10,18-20,22,27-30,42H,6,11-17H2,(H2,37,48)(H,40,43)(H,44,51)(H,45,50)(H,46,49)(H,47,52)(H4,38,39,41)/t27-,28-,29-,30-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
210n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50034910
PNG
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
246n/an/an/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of europium labeled NDP-alpha-MSH from human MC4R expressed in HEK293 cells


J Med Chem 49: 4745-61 (2006)


Article DOI: 10.1021/jm060384p
BindingDB Entry DOI: 10.7270/Q29W0F4J
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131249
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES CS(=O)(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C33H43N11O6S/c1-51(49,50)44-28(16-22-18-37-19-40-22)32(48)43-27(14-20-8-3-2-4-9-20)31(47)41-25(12-7-13-38-33(35)36)30(46)42-26(29(34)45)15-21-17-39-24-11-6-5-10-23(21)24/h2-6,8-11,17-19,25-28,39,44H,7,12-16H2,1H3,(H2,34,45)(H,37,40)(H,41,47)(H,42,46)(H,43,48)(H4,35,36,38)/t25-,26-,27-,28-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
260n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC4R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50034910
PNG
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
280n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human melanocortin 4 receptor (hMC4R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M3 and M4)


(Homo sapiens (Human))
BDBM50131240
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES CC(C)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C36H47N11O5/c1-21(2)32(49)46-30(17-24-19-40-20-43-24)35(52)47-29(15-22-9-4-3-5-10-22)34(51)44-27(13-8-14-41-36(38)39)33(50)45-28(31(37)48)16-23-18-42-26-12-7-6-11-25(23)26/h3-7,9-12,18-21,27-30,42H,8,13-17H2,1-2H3,(H2,37,48)(H,40,43)(H,44,51)(H,45,50)(H,46,49)(H,47,52)(H4,38,39,41)/t27-,28-,29-,30-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
280n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131241
PNG
((S)-2-{(S)-2-[(S)-2-(2-Cyano-acetylamino)-3-(3H-im...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CC#N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C35H42N12O5/c36-13-12-30(48)44-29(17-23-19-40-20-43-23)34(52)47-28(15-21-7-2-1-3-8-21)33(51)45-26(11-6-14-41-35(38)39)32(50)46-27(31(37)49)16-22-18-42-25-10-5-4-9-24(22)25/h1-5,7-10,18-20,26-29,42H,6,11-12,14-17H2,(H2,37,49)(H,40,43)(H,44,48)(H,45,51)(H,46,50)(H,47,52)(H4,38,39,41)/t26-,27-,28-,29-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
350n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50131254
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES COCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C35H45N11O6/c1-52-19-30(47)43-29(16-23-18-39-20-42-23)34(51)46-28(14-21-8-3-2-4-9-21)33(50)44-26(12-7-13-40-35(37)38)32(49)45-27(31(36)48)15-22-17-41-25-11-6-5-10-24(22)25/h2-6,8-11,17-18,20,26-29,41H,7,12-16,19H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,37,38,40)/t26-,27-,28-,29-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
350n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human melanocortin 4 receptor (hMC4R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131254
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES COCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C35H45N11O6/c1-52-19-30(47)43-29(16-23-18-39-20-42-23)34(51)46-28(14-21-8-3-2-4-9-21)33(50)44-26(12-7-13-40-35(37)38)32(49)45-27(31(36)48)15-22-17-41-25-11-6-5-10-24(22)25/h2-6,8-11,17-18,20,26-29,41H,7,12-16,19H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,37,38,40)/t26-,27-,28-,29-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
380n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50131255
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-2-(2-hydroxy-acetyla...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H43N11O6/c35-30(48)26(14-21-16-40-24-10-5-4-9-23(21)24)44-31(49)25(11-6-12-39-34(36)37)43-32(50)27(13-20-7-2-1-3-8-20)45-33(51)28(42-29(47)18-46)15-22-17-38-19-41-22/h1-5,7-10,16-17,19,25-28,40,46H,6,11-15,18H2,(H2,35,48)(H,38,41)(H,42,47)(H,43,50)(H,44,49)(H,45,51)(H4,36,37,39)/t25-,26-,27-,28-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
440n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
In vitro agonist potency was evaluated in HEK293 cells transfected with human melanocortin receptor (hMC1R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M3 and M4)


(Homo sapiens (Human))
BDBM50131248
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES CCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C35H45N11O5/c1-2-30(47)43-29(17-23-19-39-20-42-23)34(51)46-28(15-21-9-4-3-5-10-21)33(50)44-26(13-8-14-40-35(37)38)32(49)45-27(31(36)48)16-22-18-41-25-12-7-6-11-24(22)25/h3-7,9-12,18-20,26-29,41H,2,8,13-17H2,1H3,(H2,36,48)(H,39,42)(H,43,47)(H,44,50)(H,45,49)(H,46,51)(H4,37,38,40)/t26-,27-,28-,29-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
540n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M3 and M4)


(Homo sapiens (Human))
BDBM50131238
PNG
((S)-2-{(S)-2-[(S)-2-Butyrylamino-3-(3H-imidazol-4-...)
Show SMILES CCCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C36H47N11O5/c1-2-9-31(48)44-30(18-24-20-40-21-43-24)35(52)47-29(16-22-10-4-3-5-11-22)34(51)45-27(14-8-15-41-36(38)39)33(50)46-28(32(37)49)17-23-19-42-26-13-7-6-12-25(23)26/h3-7,10-13,19-21,27-30,42H,2,8-9,14-18H2,1H3,(H2,37,49)(H,40,43)(H,44,48)(H,45,51)(H,46,50)(H,47,52)(H4,38,39,41)/t27-,28-,29-,30-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
580n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50131255
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-2-(2-hydroxy-acetyla...)
Show SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CO)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H43N11O6/c35-30(48)26(14-21-16-40-24-10-5-4-9-23(21)24)44-31(49)25(11-6-12-39-34(36)37)43-32(50)27(13-20-7-2-1-3-8-20)45-33(51)28(42-29(47)18-46)15-22-17-38-19-41-22/h1-5,7-10,16-17,19,25-28,40,46H,6,11-15,18H2,(H2,35,48)(H,38,41)(H,42,47)(H,43,50)(H,44,49)(H,45,51)(H4,36,37,39)/t25-,26-,27-,28-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
630n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50111167
PNG
(2-Amino-5-guanidino-pentanoic acid naphthalen-1-yl...)
Show SMILES N[C@@H](CCCNC(N)=N)C(=O)N(Cc1ccc2ccccc2c1)Cc1cccc2ccccc12
Show InChI InChI=1S/C28H31N5O/c29-26(13-6-16-32-28(30)31)27(34)33(18-20-14-15-21-7-1-2-9-23(21)17-20)19-24-11-5-10-22-8-3-4-12-25(22)24/h1-5,7-12,14-15,17,26H,6,13,16,18-19,29H2,(H4,30,31,32)/t26-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
690n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Tested for its binding affinity towards human recombinant Melanocortin 1 receptor by using radioligand binding assay


Bioorg Med Chem Lett 12: 1035-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00088-4
BindingDB Entry DOI: 10.7270/Q2D799RR
More data for this
Ligand-Target Pair
Melanocortin receptor (M3 and M4)


(Homo sapiens (Human))
BDBM50034910
PNG
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
770n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M3 and M4)


(Homo sapiens (Human))
BDBM50131239
PNG
(2-{(S)-2-[(S)-2-Amino-3-(3H-imidazol-4-yl)-propion...)
Show SMILES N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C32H41N11O4/c33-23(15-21-17-37-18-40-21)29(45)43-27(13-19-7-2-1-3-8-19)31(47)41-25(11-6-12-38-32(35)36)30(46)42-26(28(34)44)14-20-16-39-24-10-5-4-9-22(20)24/h1-5,7-10,16-18,23,25-27,39H,6,11-15,33H2,(H2,34,44)(H,37,40)(H,41,47)(H,42,46)(H,43,45)(H4,35,36,38)/t23-,25-,26-,27-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
890n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M4 and M5)


(Homo sapiens (Human))
BDBM50111181
PNG
((2R)-5-[(E)-[amino(azaniumyl)methylidene]amino]-2-...)
Show SMILES COc1ccc(CN[C@H](CCCNC([NH3+])=N)C(O)=O)cc1OC
Show InChI InChI=1S/C15H24N4O4/c1-22-12-6-5-10(8-13(12)23-2)9-19-11(14(20)21)4-3-7-18-15(16)17/h5-6,8,11,19H,3-4,7,9H2,1-2H3,(H,20,21)(H4,16,17,18)/p+1/t11-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 1 receptor


Bioorg Med Chem Lett 12: 1039-42 (2002)


Article DOI: 10.1016/s0960-894x(02)00089-6
BindingDB Entry DOI: 10.7270/Q2833SKD
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50111181
PNG
((2R)-5-[(E)-[amino(azaniumyl)methylidene]amino]-2-...)
Show SMILES COc1ccc(CN[C@H](CCCNC([NH3+])=N)C(O)=O)cc1OC
Show InChI InChI=1S/C15H24N4O4/c1-22-12-6-5-10(8-13(12)23-2)9-19-11(14(20)21)4-3-7-18-15(16)17/h5-6,8,11,19H,3-4,7,9H2,1-2H3,(H,20,21)(H4,16,17,18)/p+1/t11-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 5 receptor


Bioorg Med Chem Lett 12: 1039-42 (2002)


Article DOI: 10.1016/s0960-894x(02)00089-6
BindingDB Entry DOI: 10.7270/Q2833SKD
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50111181
PNG
((2R)-5-[(E)-[amino(azaniumyl)methylidene]amino]-2-...)
Show SMILES COc1ccc(CN[C@H](CCCNC([NH3+])=N)C(O)=O)cc1OC
Show InChI InChI=1S/C15H24N4O4/c1-22-12-6-5-10(8-13(12)23-2)9-19-11(14(20)21)4-3-7-18-15(16)17/h5-6,8,11,19H,3-4,7,9H2,1-2H3,(H,20,21)(H4,16,17,18)/p+1/t11-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 3 receptor


Bioorg Med Chem Lett 12: 1039-42 (2002)


Article DOI: 10.1016/s0960-894x(02)00089-6
BindingDB Entry DOI: 10.7270/Q2833SKD
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50111181
PNG
((2R)-5-[(E)-[amino(azaniumyl)methylidene]amino]-2-...)
Show SMILES COc1ccc(CN[C@H](CCCNC([NH3+])=N)C(O)=O)cc1OC
Show InChI InChI=1S/C15H24N4O4/c1-22-12-6-5-10(8-13(12)23-2)9-19-11(14(20)21)4-3-7-18-15(16)17/h5-6,8,11,19H,3-4,7,9H2,1-2H3,(H,20,21)(H4,16,17,18)/p+1/t11-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 5 receptor


Bioorg Med Chem Lett 12: 1039-42 (2002)


Article DOI: 10.1016/s0960-894x(02)00089-6
BindingDB Entry DOI: 10.7270/Q2833SKD
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50111181
PNG
((2R)-5-[(E)-[amino(azaniumyl)methylidene]amino]-2-...)
Show SMILES COc1ccc(CN[C@H](CCCNC([NH3+])=N)C(O)=O)cc1OC
Show InChI InChI=1S/C15H24N4O4/c1-22-12-6-5-10(8-13(12)23-2)9-19-11(14(20)21)4-3-7-18-15(16)17/h5-6,8,11,19H,3-4,7,9H2,1-2H3,(H,20,21)(H4,16,17,18)/p+1/t11-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 3 receptor


Bioorg Med Chem Lett 12: 1039-42 (2002)


Article DOI: 10.1016/s0960-894x(02)00089-6
BindingDB Entry DOI: 10.7270/Q2833SKD
More data for this
Ligand-Target Pair
Melanocortin receptor (M3 and M4)


(Homo sapiens (Human))
BDBM50111181
PNG
((2R)-5-[(E)-[amino(azaniumyl)methylidene]amino]-2-...)
Show SMILES COc1ccc(CN[C@H](CCCNC([NH3+])=N)C(O)=O)cc1OC
Show InChI InChI=1S/C15H24N4O4/c1-22-12-6-5-10(8-13(12)23-2)9-19-11(14(20)21)4-3-7-18-15(16)17/h5-6,8,11,19H,3-4,7,9H2,1-2H3,(H,20,21)(H4,16,17,18)/p+1/t11-/m1/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 3 receptor


Bioorg Med Chem Lett 12: 1039-42 (2002)


Article DOI: 10.1016/s0960-894x(02)00089-6
BindingDB Entry DOI: 10.7270/Q2833SKD
More data for this
Ligand-Target Pair
Melanocyte-stimulating hormone receptor


(Homo sapiens (Human))
BDBM50111181
PNG
((2R)-5-[(E)-[amino(azaniumyl)methylidene]amino]-2-...)
Show SMILES COc1ccc(CN[C@H](CCCNC([NH3+])=N)C(O)=O)cc1OC
Show InChI InChI=1S/C15H24N4O4/c1-22-12-6-5-10(8-13(12)23-2)9-19-11(14(20)21)4-3-7-18-15(16)17/h5-6,8,11,19H,3-4,7,9H2,1-2H3,(H,20,21)(H4,16,17,18)/p+1/t11-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 1 receptor


Bioorg Med Chem Lett 12: 1039-42 (2002)


Article DOI: 10.1016/s0960-894x(02)00089-6
BindingDB Entry DOI: 10.7270/Q2833SKD
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50111181
PNG
((2R)-5-[(E)-[amino(azaniumyl)methylidene]amino]-2-...)
Show SMILES COc1ccc(CN[C@H](CCCNC([NH3+])=N)C(O)=O)cc1OC
Show InChI InChI=1S/C15H24N4O4/c1-22-12-6-5-10(8-13(12)23-2)9-19-11(14(20)21)4-3-7-18-15(16)17/h5-6,8,11,19H,3-4,7,9H2,1-2H3,(H,20,21)(H4,16,17,18)/p+1/t11-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
>1.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Binding affinity in competition with [125I]NDP-MSH on recombinant melanocortin 4 receptor


Bioorg Med Chem Lett 12: 1039-42 (2002)


Article DOI: 10.1016/s0960-894x(02)00089-6
BindingDB Entry DOI: 10.7270/Q2833SKD
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50111167
PNG
(2-Amino-5-guanidino-pentanoic acid naphthalen-1-yl...)
Show SMILES N[C@@H](CCCNC(N)=N)C(=O)N(Cc1ccc2ccccc2c1)Cc1cccc2ccccc12
Show InChI InChI=1S/C28H31N5O/c29-26(13-6-16-32-28(30)31)27(34)33(18-20-14-15-21-7-1-2-9-23(21)17-20)19-24-11-5-10-22-8-3-4-12-25(22)24/h1-5,7-12,14-15,17,26H,6,13,16,18-19,29H2,(H4,30,31,32)/t26-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.20E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Tested for its binding affinity towards human recombinant Melanocortin 1 receptor by using radioligand binding assay


Bioorg Med Chem Lett 12: 1035-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00088-4
BindingDB Entry DOI: 10.7270/Q2D799RR
More data for this
Ligand-Target Pair
Melanocortin receptor (M3 and M4)


(Homo sapiens (Human))
BDBM50131249
PNG
((S)-5-Guanidino-2-{(S)-2-[(S)-3-(3H-imidazol-4-yl)...)
Show SMILES CS(=O)(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C33H43N11O6S/c1-51(49,50)44-28(16-22-18-37-19-40-22)32(48)43-27(14-20-8-3-2-4-9-20)31(47)41-25(12-7-13-38-33(35)36)30(46)42-26(29(34)45)15-21-17-39-24-11-6-5-10-23(21)24/h2-6,8-11,17-19,25-28,39,44H,7,12-16H2,1H3,(H2,34,45)(H,37,40)(H,41,47)(H,42,46)(H,43,48)(H4,35,36,38)/t25-,26-,27-,28-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.90E+3n/an/an/an/an/an/an/an/a



University of Cincinnati

Curated by ChEMBL


Assay Description
Binding affinity towards human Melanocortin 3 receptor (hMC3R)


Bioorg Med Chem Lett 13: 2647-50 (2003)


Article DOI: 10.1016/s0960-894x(03)00552-3
BindingDB Entry DOI: 10.7270/Q2474BD9
More data for this
Ligand-Target Pair
Melanocortin receptor (M1 and M4)


(Homo sapiens (Human))
BDBM50111167
PNG
(2-Amino-5-guanidino-pentanoic acid naphthalen-1-yl...)
Show SMILES N[C@@H](CCCNC(N)=N)C(=O)N(Cc1ccc2ccccc2c1)Cc1cccc2ccccc12
Show InChI InChI=1S/C28H31N5O/c29-26(13-6-16-32-28(30)31)27(34)33(18-20-14-15-21-7-1-2-9-23(21)17-20)19-24-11-5-10-22-8-3-4-12-25(22)24/h1-5,7-12,14-15,17,26H,6,13,16,18-19,29H2,(H4,30,31,32)/t26-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.10E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Tested for its binding affinity towards human recombinant Melanocortin 4 receptor by using radioligand binding assay


Bioorg Med Chem Lett 12: 1035-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00088-4
BindingDB Entry DOI: 10.7270/Q2D799RR
More data for this
Ligand-Target Pair
Melanocortin receptor (M4 and M5)


(Homo sapiens (Human))
BDBM50111167
PNG
(2-Amino-5-guanidino-pentanoic acid naphthalen-1-yl...)
Show SMILES N[C@@H](CCCNC(N)=N)C(=O)N(Cc1ccc2ccccc2c1)Cc1cccc2ccccc12
Show InChI InChI=1S/C28H31N5O/c29-26(13-6-16-32-28(30)31)27(34)33(18-20-14-15-21-7-1-2-9-23(21)17-20)19-24-11-5-10-22-8-3-4-12-25(22)24/h1-5,7-12,14-15,17,26H,6,13,16,18-19,29H2,(H4,30,31,32)/t26-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.50E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Tested for its binding affinity towards human recombinant Melanocortin 5 receptor by using radioligand binding assay


Bioorg Med Chem Lett 12: 1035-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00088-4
BindingDB Entry DOI: 10.7270/Q2D799RR
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50111167
PNG
(2-Amino-5-guanidino-pentanoic acid naphthalen-1-yl...)
Show SMILES N[C@@H](CCCNC(N)=N)C(=O)N(Cc1ccc2ccccc2c1)Cc1cccc2ccccc12
Show InChI InChI=1S/C28H31N5O/c29-26(13-6-16-32-28(30)31)27(34)33(18-20-14-15-21-7-1-2-9-23(21)17-20)19-24-11-5-10-22-8-3-4-12-25(22)24/h1-5,7-12,14-15,17,26H,6,13,16,18-19,29H2,(H4,30,31,32)/t26-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.70E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Tested for its binding affinity towards human recombinant Melanocortin 5 receptor by using radioligand binding assay


Bioorg Med Chem Lett 12: 1035-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00088-4
BindingDB Entry DOI: 10.7270/Q2D799RR
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50034910
PNG
((S)-2-{(S)-2-[(S)-2-acetylamino-3-(3H-imidazol-4-y...)
Show SMILES CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C34H43N11O5/c1-20(46)42-29(16-23-18-38-19-41-23)33(50)45-28(14-21-8-3-2-4-9-21)32(49)43-26(12-7-13-39-34(36)37)31(48)44-27(30(35)47)15-22-17-40-25-11-6-5-10-24(22)25/h2-6,8-11,17-19,26-29,40H,7,12-16H2,1H3,(H2,35,47)(H,38,41)(H,42,46)(H,43,49)(H,44,48)(H,45,50)(H4,36,37,39)/t26-,27-,28-,29-/m0/s1
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2.87E+3n/an/an/an/an/an/an/an/a



Procter & Gamble Pharmaceuticals

Curated by ChEMBL


Assay Description
Displacement of europium labeled NDP-alpha-MSH from human MC3R expressed in HEK293 cells


J Med Chem 49: 4745-61 (2006)


Article DOI: 10.1021/jm060384p
BindingDB Entry DOI: 10.7270/Q29W0F4J
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50111167
PNG
(2-Amino-5-guanidino-pentanoic acid naphthalen-1-yl...)
Show SMILES N[C@@H](CCCNC(N)=N)C(=O)N(Cc1ccc2ccccc2c1)Cc1cccc2ccccc12
Show InChI InChI=1S/C28H31N5O/c29-26(13-6-16-32-28(30)31)27(34)33(18-20-14-15-21-7-1-2-9-23(21)17-20)19-24-11-5-10-22-8-3-4-12-25(22)24/h1-5,7-12,14-15,17,26H,6,13,16,18-19,29H2,(H4,30,31,32)/t26-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.40E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Tested for its binding affinity towards human recombinant Melanocortin 4 receptor by using radioligand binding assay


Bioorg Med Chem Lett 12: 1035-8 (2002)


Article DOI: 10.1016/s0960-894x(02)00088-4
BindingDB Entry DOI: 10.7270/Q2D799RR
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 122 total )  |  Next  |  Last  >>