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Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 343.4
BDBM50217716
Wt: 333.4
BDBM50217718
Wt: 347.4
BDBM50217777
Wt: 347.4
BDBM50217725
Wt: 347.4
BDBM50217783
Wt: 273.3
BDBM50217668
Wt: 349.4
BDBM50217790
Wt: 347.4
BDBM50217633
Wt: 347.4
BDBM50217768
Wt: 335.4
BDBM50217692
Wt: 349.4
BDBM50217695
Wt: 349.4
BDBM50217710
Wt: 355.5
BDBM50217734
Wt: 356.4
BDBM50374117
Wt: 308.3
BDBM50374122
Displayed 1 to 15 (of 552 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 56 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Melanocortin receptor 1


(Mus musculus)
BDBM50217783
PNG
((E)-N-(3-aminopropyl)-N-(2-methyl-3-phenylallyl)-1...)
Show SMILES C\C(CN(CCCN)C(=O)c1c[nH]c2ccccc12)=C/c1ccccc1
Show InChI InChI=1S/C22H25N3O/c1-17(14-18-8-3-2-4-9-18)16-25(13-7-12-23)22(26)20-15-24-21-11-6-5-10-19(20)21/h2-6,8-11,14-15,24H,7,12-13,16,23H2,1H3/b17-14+
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850n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217783
PNG
((E)-N-(3-aminopropyl)-N-(2-methyl-3-phenylallyl)-1...)
Show SMILES C\C(CN(CCCN)C(=O)c1c[nH]c2ccccc12)=C/c1ccccc1
Show InChI InChI=1S/C22H25N3O/c1-17(14-18-8-3-2-4-9-18)16-25(13-7-12-23)22(26)20-15-24-21-11-6-5-10-19(20)21/h2-6,8-11,14-15,24H,7,12-13,16,23H2,1H3/b17-14+
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930n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217716
PNG
(CHEMBL235797 | N-(2-aminoethyl)-N-(naphthalen-2-yl...)
Show SMILES NCCN(Cc1ccc2ccccc2c1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C22H21N3O/c23-11-12-25(15-16-9-10-17-5-1-2-6-18(17)13-16)22(26)20-14-24-21-8-4-3-7-19(20)21/h1-10,13-14,24H,11-12,15,23H2
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3.60E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217777
PNG
(CHEMBL237079 | N-(2-aminoethyl)-2-(1H-indol-3-yl)-...)
Show SMILES NCCN(C1CCc2ccccc2C1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-11-12-25(19-10-9-16-5-1-2-6-17(16)13-19)22(26)14-18-15-24-21-8-4-3-7-20(18)21/h1-8,15,19,24H,9-14,23H2
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4.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217768
PNG
(CHEMBL238180 | N-(3-aminopropyl)-N-(1,2,3,4-tetrah...)
Show SMILES NCCCN(C1CCc2ccccc2C1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-12-5-13-25(18-11-10-16-6-1-2-7-17(16)14-18)22(26)20-15-24-21-9-4-3-8-19(20)21/h1-4,6-9,15,18,24H,5,10-14,23H2
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4.80E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217695
PNG
(CHEMBL237743 | N-(3-aminopropyl)-2-(1H-indol-3-yl)...)
Show SMILES NCCCN(CCCc1ccccc1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-13-7-15-25(14-6-10-18-8-2-1-3-9-18)22(26)16-19-17-24-21-12-5-4-11-20(19)21/h1-5,8-9,11-12,17,24H,6-7,10,13-16,23H2
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5.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217695
PNG
(CHEMBL237743 | N-(3-aminopropyl)-2-(1H-indol-3-yl)...)
Show SMILES NCCCN(CCCc1ccccc1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-13-7-15-25(14-6-10-18-8-2-1-3-9-18)22(26)16-19-17-24-21-12-5-4-11-20(19)21/h1-5,8-9,11-12,17,24H,6-7,10,13-16,23H2
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5.70E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217734
PNG
(CHEMBL237693 | N-(5-aminopentyl)-N-cycloheptyl-2-(...)
Show SMILES NCCCCCN(C1CCCCCC1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H33N3O/c23-14-8-3-9-15-25(19-10-4-1-2-5-11-19)22(26)16-18-17-24-21-13-7-6-12-20(18)21/h6-7,12-13,17,19,24H,1-5,8-11,14-16,23H2
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6.00E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217633
PNG
(CHEMBL438672 | N-(3-aminopropyl)-N-cinnamyl-2-(1H-...)
Show SMILES NCCCN(C\C=C\c1ccccc1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-13-7-15-25(14-6-10-18-8-2-1-3-9-18)22(26)16-19-17-24-21-12-5-4-11-20(19)21/h1-6,8-12,17,24H,7,13-16,23H2/b10-6+
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6.40E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217783
PNG
((E)-N-(3-aminopropyl)-N-(2-methyl-3-phenylallyl)-1...)
Show SMILES C\C(CN(CCCN)C(=O)c1c[nH]c2ccccc12)=C/c1ccccc1
Show InChI InChI=1S/C22H25N3O/c1-17(14-18-8-3-2-4-9-18)16-25(13-7-12-23)22(26)20-15-24-21-11-6-5-10-19(20)21/h2-6,8-11,14-15,24H,7,12-13,16,23H2,1H3/b17-14+
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7.40E+3n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217718
PNG
(CHEMBL237957 | N-(3-aminopropyl)-N-cinnamyl-1H-ind...)
Show SMILES NCCCN(C\C=C\c1ccccc1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H23N3O/c22-13-7-15-24(14-6-10-17-8-2-1-3-9-17)21(25)19-16-23-20-12-5-4-11-18(19)20/h1-6,8-12,16,23H,7,13-15,22H2/b10-6+
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1.20E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217725
PNG
(CHEMBL237719 | N-(2-aminoethyl)-N-cinnamyl-3-(1H-i...)
Show SMILES NCCN(C\C=C\c1ccccc1)C(=O)CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-14-16-25(15-6-9-18-7-2-1-3-8-18)22(26)13-12-19-17-24-21-11-5-4-10-20(19)21/h1-11,17,24H,12-16,23H2/b9-6+
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1.30E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217695
PNG
(CHEMBL237743 | N-(3-aminopropyl)-2-(1H-indol-3-yl)...)
Show SMILES NCCCN(CCCc1ccccc1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-13-7-15-25(14-6-10-18-8-2-1-3-9-18)22(26)16-19-17-24-21-12-5-4-11-20(19)21/h1-5,8-9,11-12,17,24H,6-7,10,13-16,23H2
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1.30E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217734
PNG
(CHEMBL237693 | N-(5-aminopentyl)-N-cycloheptyl-2-(...)
Show SMILES NCCCCCN(C1CCCCCC1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H33N3O/c23-14-8-3-9-15-25(19-10-4-1-2-5-11-19)22(26)16-18-17-24-21-13-7-6-12-20(18)21/h6-7,12-13,17,19,24H,1-5,8-11,14-16,23H2
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1.40E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217710
PNG
(CHEMBL396341 | N-(3-aminopropyl)-N-benzyl-4-(1H-in...)
Show SMILES NCCCN(Cc1ccccc1)C(=O)CCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-14-7-15-25(17-18-8-2-1-3-9-18)22(26)13-6-10-19-16-24-21-12-5-4-11-20(19)21/h1-5,8-9,11-12,16,24H,6-7,10,13-15,17,23H2
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1.60E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217777
PNG
(CHEMBL237079 | N-(2-aminoethyl)-2-(1H-indol-3-yl)-...)
Show SMILES NCCN(C1CCc2ccccc2C1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-11-12-25(19-10-9-16-5-1-2-6-17(16)13-19)22(26)14-18-15-24-21-8-4-3-7-20(18)21/h1-8,15,19,24H,9-14,23H2
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1.60E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217734
PNG
(CHEMBL237693 | N-(5-aminopentyl)-N-cycloheptyl-2-(...)
Show SMILES NCCCCCN(C1CCCCCC1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H33N3O/c23-14-8-3-9-15-25(19-10-4-1-2-5-11-19)22(26)16-18-17-24-21-13-7-6-12-20(18)21/h6-7,12-13,17,19,24H,1-5,8-11,14-16,23H2
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1.60E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217718
PNG
(CHEMBL237957 | N-(3-aminopropyl)-N-cinnamyl-1H-ind...)
Show SMILES NCCCN(C\C=C\c1ccccc1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H23N3O/c22-13-7-15-24(14-6-10-17-8-2-1-3-9-17)21(25)19-16-23-20-12-5-4-11-18(19)20/h1-6,8-12,16,23H,7,13-15,22H2/b10-6+
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1.70E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217725
PNG
(CHEMBL237719 | N-(2-aminoethyl)-N-cinnamyl-3-(1H-i...)
Show SMILES NCCN(C\C=C\c1ccccc1)C(=O)CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-14-16-25(15-6-9-18-7-2-1-3-8-18)22(26)13-12-19-17-24-21-11-5-4-10-20(19)21/h1-11,17,24H,12-16,23H2/b9-6+
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1.70E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217710
PNG
(CHEMBL396341 | N-(3-aminopropyl)-N-benzyl-4-(1H-in...)
Show SMILES NCCCN(Cc1ccccc1)C(=O)CCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-14-7-15-25(17-18-8-2-1-3-9-18)22(26)13-6-10-19-16-24-21-12-5-4-11-20(19)21/h1-5,8-9,11-12,16,24H,6-7,10,13-15,17,23H2
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1.70E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217790
PNG
(CHEMBL396655 | N-(2-aminoethyl)-3-(1H-indol-3-yl)-...)
Show SMILES NCCN(CCCc1ccccc1)C(=O)CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-14-16-25(15-6-9-18-7-2-1-3-8-18)22(26)13-12-19-17-24-21-11-5-4-10-20(19)21/h1-5,7-8,10-11,17,24H,6,9,12-16,23H2
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PubMed
2.00E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217633
PNG
(CHEMBL438672 | N-(3-aminopropyl)-N-cinnamyl-2-(1H-...)
Show SMILES NCCCN(C\C=C\c1ccccc1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-13-7-15-25(14-6-10-18-8-2-1-3-9-18)22(26)16-19-17-24-21-12-5-4-11-20(19)21/h1-6,8-12,17,24H,7,13-16,23H2/b10-6+
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2.10E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217790
PNG
(CHEMBL396655 | N-(2-aminoethyl)-3-(1H-indol-3-yl)-...)
Show SMILES NCCN(CCCc1ccccc1)C(=O)CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-14-16-25(15-6-9-18-7-2-1-3-8-18)22(26)13-12-19-17-24-21-11-5-4-10-20(19)21/h1-5,7-8,10-11,17,24H,6,9,12-16,23H2
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2.10E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217692
PNG
(CHEMBL396598 | N-(2-aminoethyl)-N-benzyl-4-(1H-ind...)
Show SMILES NCCN(Cc1ccccc1)C(=O)CCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C21H25N3O/c22-13-14-24(16-17-7-2-1-3-8-17)21(25)12-6-9-18-15-23-20-11-5-4-10-19(18)20/h1-5,7-8,10-11,15,23H,6,9,12-14,16,22H2
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2.10E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217692
PNG
(CHEMBL396598 | N-(2-aminoethyl)-N-benzyl-4-(1H-ind...)
Show SMILES NCCN(Cc1ccccc1)C(=O)CCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C21H25N3O/c22-13-14-24(16-17-7-2-1-3-8-17)21(25)12-6-9-18-15-23-20-11-5-4-10-19(18)20/h1-5,7-8,10-11,15,23H,6,9,12-14,16,22H2
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2.20E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217718
PNG
(CHEMBL237957 | N-(3-aminopropyl)-N-cinnamyl-1H-ind...)
Show SMILES NCCCN(C\C=C\c1ccccc1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H23N3O/c22-13-7-15-24(14-6-10-17-8-2-1-3-9-17)21(25)19-16-23-20-12-5-4-11-18(19)20/h1-6,8-12,16,23H,7,13-15,22H2/b10-6+
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2.30E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217768
PNG
(CHEMBL238180 | N-(3-aminopropyl)-N-(1,2,3,4-tetrah...)
Show SMILES NCCCN(C1CCc2ccccc2C1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-12-5-13-25(18-11-10-16-6-1-2-7-17(16)14-18)22(26)20-15-24-21-9-4-3-8-19(20)21/h1-4,6-9,15,18,24H,5,10-14,23H2
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2.30E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217783
PNG
((E)-N-(3-aminopropyl)-N-(2-methyl-3-phenylallyl)-1...)
Show SMILES C\C(CN(CCCN)C(=O)c1c[nH]c2ccccc12)=C/c1ccccc1
Show InChI InChI=1S/C22H25N3O/c1-17(14-18-8-3-2-4-9-18)16-25(13-7-12-23)22(26)20-15-24-21-11-6-5-10-19(20)21/h2-6,8-11,14-15,24H,7,12-13,16,23H2,1H3/b17-14+
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2.40E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217710
PNG
(CHEMBL396341 | N-(3-aminopropyl)-N-benzyl-4-(1H-in...)
Show SMILES NCCCN(Cc1ccccc1)C(=O)CCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-14-7-15-25(17-18-8-2-1-3-9-18)22(26)13-6-10-19-16-24-21-12-5-4-11-20(19)21/h1-5,8-9,11-12,16,24H,6-7,10,13-15,17,23H2
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PubMed
2.50E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217633
PNG
(CHEMBL438672 | N-(3-aminopropyl)-N-cinnamyl-2-(1H-...)
Show SMILES NCCCN(C\C=C\c1ccccc1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-13-7-15-25(14-6-10-18-8-2-1-3-9-18)22(26)16-19-17-24-21-12-5-4-11-20(19)21/h1-6,8-12,17,24H,7,13-16,23H2/b10-6+
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2.60E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217716
PNG
(CHEMBL235797 | N-(2-aminoethyl)-N-(naphthalen-2-yl...)
Show SMILES NCCN(Cc1ccc2ccccc2c1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C22H21N3O/c23-11-12-25(15-16-9-10-17-5-1-2-6-18(17)13-16)22(26)20-14-24-21-8-4-3-7-19(20)21/h1-10,13-14,24H,11-12,15,23H2
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PubMed
2.70E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217777
PNG
(CHEMBL237079 | N-(2-aminoethyl)-2-(1H-indol-3-yl)-...)
Show SMILES NCCN(C1CCc2ccccc2C1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-11-12-25(19-10-9-16-5-1-2-6-17(16)13-19)22(26)14-18-15-24-21-8-4-3-7-20(18)21/h1-8,15,19,24H,9-14,23H2
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2.90E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217695
PNG
(CHEMBL237743 | N-(3-aminopropyl)-2-(1H-indol-3-yl)...)
Show SMILES NCCCN(CCCc1ccccc1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-13-7-15-25(14-6-10-18-8-2-1-3-9-18)22(26)16-19-17-24-21-12-5-4-11-20(19)21/h1-5,8-9,11-12,17,24H,6-7,10,13-16,23H2
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3.20E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217734
PNG
(CHEMBL237693 | N-(5-aminopentyl)-N-cycloheptyl-2-(...)
Show SMILES NCCCCCN(C1CCCCCC1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H33N3O/c23-14-8-3-9-15-25(19-10-4-1-2-5-11-19)22(26)16-18-17-24-21-13-7-6-12-20(18)21/h6-7,12-13,17,19,24H,1-5,8-11,14-16,23H2
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3.50E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217777
PNG
(CHEMBL237079 | N-(2-aminoethyl)-2-(1H-indol-3-yl)-...)
Show SMILES NCCN(C1CCc2ccccc2C1)C(=O)Cc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-11-12-25(19-10-9-16-5-1-2-6-17(16)13-19)22(26)14-18-15-24-21-8-4-3-7-20(18)21/h1-8,15,19,24H,9-14,23H2
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4.20E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217710
PNG
(CHEMBL396341 | N-(3-aminopropyl)-N-benzyl-4-(1H-in...)
Show SMILES NCCCN(Cc1ccccc1)C(=O)CCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-14-7-15-25(17-18-8-2-1-3-9-18)22(26)13-6-10-19-16-24-21-12-5-4-11-20(19)21/h1-5,8-9,11-12,16,24H,6-7,10,13-15,17,23H2
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4.50E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217692
PNG
(CHEMBL396598 | N-(2-aminoethyl)-N-benzyl-4-(1H-ind...)
Show SMILES NCCN(Cc1ccccc1)C(=O)CCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C21H25N3O/c22-13-14-24(16-17-7-2-1-3-8-17)21(25)12-6-9-18-15-23-20-11-5-4-10-19(18)20/h1-5,7-8,10-11,15,23H,6,9,12-14,16,22H2
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4.90E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217725
PNG
(CHEMBL237719 | N-(2-aminoethyl)-N-cinnamyl-3-(1H-i...)
Show SMILES NCCN(C\C=C\c1ccccc1)C(=O)CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-14-16-25(15-6-9-18-7-2-1-3-8-18)22(26)13-12-19-17-24-21-11-5-4-10-20(19)21/h1-11,17,24H,12-16,23H2/b9-6+
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5.10E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217716
PNG
(CHEMBL235797 | N-(2-aminoethyl)-N-(naphthalen-2-yl...)
Show SMILES NCCN(Cc1ccc2ccccc2c1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C22H21N3O/c23-11-12-25(15-16-9-10-17-5-1-2-6-18(17)13-16)22(26)20-14-24-21-8-4-3-7-19(20)21/h1-10,13-14,24H,11-12,15,23H2
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6.60E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217768
PNG
(CHEMBL238180 | N-(3-aminopropyl)-N-(1,2,3,4-tetrah...)
Show SMILES NCCCN(C1CCc2ccccc2C1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-12-5-13-25(18-11-10-16-6-1-2-7-17(16)14-18)22(26)20-15-24-21-9-4-3-8-19(20)21/h1-4,6-9,15,18,24H,5,10-14,23H2
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7.40E+4n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217725
PNG
(CHEMBL237719 | N-(2-aminoethyl)-N-cinnamyl-3-(1H-i...)
Show SMILES NCCN(C\C=C\c1ccccc1)C(=O)CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-14-16-25(15-6-9-18-7-2-1-3-8-18)22(26)13-12-19-17-24-21-11-5-4-10-20(19)21/h1-11,17,24H,12-16,23H2/b9-6+
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1.06E+5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 1


(Mus musculus)
BDBM50217668
PNG
(CHEMBL396179 | N-(4-aminobutyl)-N-isopropyl-1H-ind...)
Show SMILES CC(C)N(CCCCN)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C16H23N3O/c1-12(2)19(10-6-5-9-17)16(20)14-11-18-15-8-4-3-7-13(14)15/h3-4,7-8,11-12,18H,5-6,9-10,17H2,1-2H3
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1.06E+5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from MC1 receptor in mouse B16 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217668
PNG
(CHEMBL396179 | N-(4-aminobutyl)-N-isopropyl-1H-ind...)
Show SMILES CC(C)N(CCCCN)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C16H23N3O/c1-12(2)19(10-6-5-9-17)16(20)14-11-18-15-8-4-3-7-13(14)15/h3-4,7-8,11-12,18H,5-6,9-10,17H2,1-2H3
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1.12E+5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217790
PNG
(CHEMBL396655 | N-(2-aminoethyl)-3-(1H-indol-3-yl)-...)
Show SMILES NCCN(CCCc1ccccc1)C(=O)CCc1c[nH]c2ccccc12
Show InChI InChI=1S/C22H27N3O/c23-14-16-25(15-6-9-18-7-2-1-3-8-18)22(26)13-12-19-17-24-21-11-5-4-10-20(19)21/h1-5,7-8,10-11,17,24H,6,9,12-16,23H2
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1.27E+5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217768
PNG
(CHEMBL238180 | N-(3-aminopropyl)-N-(1,2,3,4-tetrah...)
Show SMILES NCCCN(C1CCc2ccccc2C1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C22H25N3O/c23-12-5-13-25(18-11-10-16-6-1-2-7-17(16)14-18)22(26)20-15-24-21-9-4-3-8-19(20)21/h1-4,6-9,15,18,24H,5,10-14,23H2
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1.31E+5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217716
PNG
(CHEMBL235797 | N-(2-aminoethyl)-N-(naphthalen-2-yl...)
Show SMILES NCCN(Cc1ccc2ccccc2c1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C22H21N3O/c23-11-12-25(15-16-9-10-17-5-1-2-6-18(17)13-16)22(26)20-14-24-21-8-4-3-7-19(20)21/h1-10,13-14,24H,11-12,15,23H2
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1.34E+5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 3 (MC3R)


(Homo sapiens (Human))
BDBM50217718
PNG
(CHEMBL237957 | N-(3-aminopropyl)-N-cinnamyl-1H-ind...)
Show SMILES NCCCN(C\C=C\c1ccccc1)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C21H23N3O/c22-13-7-15-24(14-6-10-17-8-2-1-3-9-17)21(25)19-16-23-20-12-5-4-11-18(19)20/h1-6,8-12,16,23H,7,13-15,22H2/b10-6+
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1.72E+5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC3 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 4


(Homo sapiens (Human))
BDBM50217668
PNG
(CHEMBL396179 | N-(4-aminobutyl)-N-isopropyl-1H-ind...)
Show SMILES CC(C)N(CCCCN)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C16H23N3O/c1-12(2)19(10-6-5-9-17)16(20)14-11-18-15-8-4-3-7-13(14)15/h3-4,7-8,11-12,18H,5-6,9-10,17H2,1-2H3
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2.22E+5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC4 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Homo sapiens (Human))
BDBM50217668
PNG
(CHEMBL396179 | N-(4-aminobutyl)-N-isopropyl-1H-ind...)
Show SMILES CC(C)N(CCCCN)C(=O)c1c[nH]c2ccccc12
Show InChI InChI=1S/C16H23N3O/c1-12(2)19(10-6-5-9-17)16(20)14-11-18-15-8-4-3-7-13(14)15/h3-4,7-8,11-12,18H,5-6,9-10,17H2,1-2H3
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2.79E+5n/an/an/an/an/an/an/an/a



Uppsala University

Curated by ChEMBL


Assay Description
Displacement of [125I]NDP-MSH from human recombinant MC5 receptor expressed in Sf9 cells


Bioorg Med Chem 15: 5787-810 (2007)


Article DOI: 10.1016/j.bmc.2007.06.003
BindingDB Entry DOI: 10.7270/Q2X066Q5
More data for this
Ligand-Target Pair
Melanocortin receptor 5 (MC5R)


(Mus musculus (Mouse))
BDBM50374117
PNG
(CHEMBL406651)
Show SMILES O=C1NC(Cc2ccccc2)C(=O)N(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C23H20N2O2/c26-22-19-13-7-8-14-21(19)25(16-18-11-5-2-6-12-18)23(27)20(24-22)15-17-9-3-1-4-10-17/h1-14,20H,15-16H2,(H,24,26)
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n/an/an/an/a>1.00E+5n/an/an/an/a



University of Florida

Curated by ChEMBL


Assay Description
Agonist activity at mouse MC5R expressed in HEK293 cells assessed as forskolin-stimulated response by beta-galactosidase reporter gene assay


J Med Chem 51: 1423-31 (2008)


Article DOI: 10.1021/jm701303z
BindingDB Entry DOI: 10.7270/Q2KH0P61
More data for this
Ligand-Target Pair
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