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Compile Data Set for Download or QSAR

Marvin 2D Structure

Wt: 353.4
BDBM128411
Wt: 383.8
BDBM128412
Wt: 359.8
BDBM128413
Wt: 351.3
BDBM128401
Wt: 359.8
BDBM128414
Wt: 353.4
BDBM128402
Wt: 323.3
BDBM128403
Wt: 349.4
BDBM128393
Wt: 337.4
BDBM128396
Wt: 385.8
BDBM128407
Wt: 339.3
BDBM128397
Wt: 373.8
BDBM128398
Wt: 343.8
BDBM128408
Wt: 378.2
BDBM128409
Wt: 373.8
BDBM128410
Displayed 1 to 15 (of 28 total )  |  Next  |  Last  >>

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 26 hits in this display   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128407
PNG
(US8802695, 23)
Show SMILES C[C@](O)(CO)c1ccc(cc1)C(=O)Nc1cc2n(cc(Cl)c2cn1)C1CC1
Show InChI InChI=1S/C20H20ClN3O3/c1-20(27,11-25)13-4-2-12(3-5-13)19(26)23-18-8-17-15(9-22-18)16(21)10-24(17)14-6-7-14/h2-5,8-10,14,25,27H,6-7,11H2,1H3,(H,22,23,26)/t20-/m0/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128398
PNG
(US8802695, 14)
Show SMILES CCn1cc(Cl)c2cnc(NC(=O)c3ccc(cc3)[C@@](C)(O)CO)cc12
Show InChI InChI=1S/C19H20ClN3O3/c1-3-23-10-15(20)14-9-21-17(8-16(14)23)22-18(25)12-4-6-13(7-5-12)19(2,26)11-24/h4-10,24,26H,3,11H2,1-2H3,(H,21,22,25)/t19-/m0/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128407
PNG
(US8802695, 23)
Show SMILES C[C@](O)(CO)c1ccc(cc1)C(=O)Nc1cc2n(cc(Cl)c2cn1)C1CC1
Show InChI InChI=1S/C20H20ClN3O3/c1-20(27,11-25)13-4-2-12(3-5-13)19(26)23-18-8-17-15(9-22-18)16(21)10-24(17)14-6-7-14/h2-5,8-10,14,25,27H,6-7,11H2,1H3,(H,22,23,26)/t20-/m0/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128396
PNG
(US8802695, 12)
Show SMILES CCn1cc(C)c2cnc(NC(=O)c3ccc(cc3)C(C)(C)O)cc12
Show InChI InChI=1S/C20H23N3O2/c1-5-23-12-13(2)16-11-21-18(10-17(16)23)22-19(24)14-6-8-15(9-7-14)20(3,4)25/h6-12,25H,5H2,1-4H3,(H,21,22,24)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128410
PNG
(US8802695, 26)
Show SMILES CCn1cc(Cl)c2cnc(NC(=O)c3ccc(cc3)[C@](C)(O)CO)cc12
Show InChI InChI=1S/C19H20ClN3O3/c1-3-23-10-15(20)14-9-21-17(8-16(14)23)22-18(25)12-4-6-13(7-5-12)19(2,26)11-24/h4-10,24,26H,3,11H2,1-2H3,(H,21,22,25)/t19-/m1/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128408
PNG
(US8802695, 24)
Show SMILES Cn1cc(Cl)c2cnc(NC(=O)c3ccc(cc3)C(C)(C)O)cc12
Show InChI InChI=1S/C18H18ClN3O2/c1-18(2,24)12-6-4-11(5-7-12)17(23)21-16-8-15-13(9-20-16)14(19)10-22(15)3/h4-10,24H,1-3H3,(H,20,21,23)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128410
PNG
(US8802695, 26)
Show SMILES CCn1cc(Cl)c2cnc(NC(=O)c3ccc(cc3)[C@](C)(O)CO)cc12
Show InChI InChI=1S/C19H20ClN3O3/c1-3-23-10-15(20)14-9-21-17(8-16(14)23)22-18(25)12-4-6-13(7-5-12)19(2,26)11-24/h4-10,24,26H,3,11H2,1-2H3,(H,21,22,25)/t19-/m1/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128402
PNG
(US8802695, 18)
Show SMILES CCn1cc(C)c2cnc(NC(=O)c3ccc(cc3)[C@@](C)(O)CO)cc12
Show InChI InChI=1S/C20H23N3O3/c1-4-23-11-13(2)16-10-21-18(9-17(16)23)22-19(25)14-5-7-15(8-6-14)20(3,26)12-24/h5-11,24,26H,4,12H2,1-3H3,(H,21,22,25)/t20-/m0/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128412
PNG
(US8802695, 28)
Show SMILES CC(C)(CO)c1ccc(cc1)C(=O)Nc1cc2n(cc(Cl)c2cn1)C1CC1
Show InChI InChI=1S/C21H22ClN3O2/c1-21(2,12-26)14-5-3-13(4-6-14)20(27)24-19-9-18-16(10-23-19)17(22)11-25(18)15-7-8-15/h3-6,9-11,15,26H,7-8,12H2,1-2H3,(H,23,24,27)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128398
PNG
(US8802695, 14)
Show SMILES CCn1cc(Cl)c2cnc(NC(=O)c3ccc(cc3)[C@@](C)(O)CO)cc12
Show InChI InChI=1S/C19H20ClN3O3/c1-3-23-10-15(20)14-9-21-17(8-16(14)23)22-18(25)12-4-6-13(7-5-12)19(2,26)11-24/h4-10,24,26H,3,11H2,1-2H3,(H,21,22,25)/t19-/m0/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128402
PNG
(US8802695, 18)
Show SMILES CCn1cc(C)c2cnc(NC(=O)c3ccc(cc3)[C@@](C)(O)CO)cc12
Show InChI InChI=1S/C20H23N3O3/c1-4-23-11-13(2)16-10-21-18(9-17(16)23)22-19(25)14-5-7-15(8-6-14)20(3,26)12-24/h5-11,24,26H,4,12H2,1-3H3,(H,21,22,25)/t20-/m0/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128408
PNG
(US8802695, 24)
Show SMILES Cn1cc(Cl)c2cnc(NC(=O)c3ccc(cc3)C(C)(C)O)cc12
Show InChI InChI=1S/C18H18ClN3O2/c1-18(2,24)12-6-4-11(5-7-12)17(23)21-16-8-15-13(9-20-16)14(19)10-22(15)3/h4-10,24H,1-3H3,(H,20,21,23)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128414
PNG
(US8802695, 31)
Show SMILES Cn1cc(Cl)c2cnc(NC(=O)c3ccc(cc3)[C@@](C)(O)CO)cc12
Show InChI InChI=1S/C18H18ClN3O3/c1-18(25,10-23)12-5-3-11(4-6-12)17(24)21-16-7-15-13(8-20-16)14(19)9-22(15)2/h3-9,23,25H,10H2,1-2H3,(H,20,21,24)/t18-/m0/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128403
PNG
(US8802695, 19)
Show SMILES Cc1cn(C)c2cc(NC(=O)c3ccc(cc3)C(C)(C)O)ncc12
Show InChI InChI=1S/C19H21N3O2/c1-12-11-22(4)16-9-17(20-10-15(12)16)21-18(23)13-5-7-14(8-6-13)19(2,3)24/h5-11,24H,1-4H3,(H,20,21,23)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128396
PNG
(US8802695, 12)
Show SMILES CCn1cc(C)c2cnc(NC(=O)c3ccc(cc3)C(C)(C)O)cc12
Show InChI InChI=1S/C20H23N3O2/c1-5-23-12-13(2)16-11-21-18(10-17(16)23)22-19(24)14-6-8-15(9-7-14)20(3,4)25/h6-12,25H,5H2,1-4H3,(H,21,22,24)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128403
PNG
(US8802695, 19)
Show SMILES Cc1cn(C)c2cc(NC(=O)c3ccc(cc3)C(C)(C)O)ncc12
Show InChI InChI=1S/C19H21N3O2/c1-12-11-22(4)16-9-17(20-10-15(12)16)21-18(23)13-5-7-14(8-6-13)19(2,3)24/h5-11,24H,1-4H3,(H,20,21,23)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128413
PNG
(US8802695, 29)
Show SMILES Cn1cc(Cl)c2cnc(NC(=O)c3ccc(cc3)[C@](C)(O)CO)cc12
Show InChI InChI=1S/C18H18ClN3O3/c1-18(25,10-23)12-5-3-11(4-6-12)17(24)21-16-7-15-13(8-20-16)14(19)9-22(15)2/h3-9,23,25H,10H2,1-2H3,(H,20,21,24)/t18-/m1/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128397
PNG
(US8802695, 13)
Show SMILES CCn1ccc2cnc(NC(=O)c3ccc(cc3)[C@@](C)(O)CO)cc12
Show InChI InChI=1S/C19H21N3O3/c1-3-22-9-8-14-11-20-17(10-16(14)22)21-18(24)13-4-6-15(7-5-13)19(2,25)12-23/h4-11,23,25H,3,12H2,1-2H3,(H,20,21,24)/t19-/m0/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128409
PNG
(US8802695, 25)
Show SMILES Cn1c(Cl)c(Cl)c2cnc(NC(=O)c3ccc(cc3)C(C)(C)O)cc12
Show InChI InChI=1S/C18H17Cl2N3O2/c1-18(2,25)11-6-4-10(5-7-11)17(24)22-14-8-13-12(9-21-14)15(19)16(20)23(13)3/h4-9,25H,1-3H3,(H,21,22,24)
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128397
PNG
(US8802695, 13)
Show SMILES CCn1ccc2cnc(NC(=O)c3ccc(cc3)[C@@](C)(O)CO)cc12
Show InChI InChI=1S/C19H21N3O3/c1-3-22-9-8-14-11-20-17(10-16(14)22)21-18(24)13-4-6-15(7-5-13)19(2,25)12-23/h4-11,23,25H,3,12H2,1-2H3,(H,20,21,24)/t19-/m0/s1
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Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128401
PNG
(US8802695, 17)
Show SMILES C[C@](O)(CO)c1ccc(cc1)C(=O)Nc1cc2n(ccc2cn1)C1CC1
Show InChI InChI=1S/C20H21N3O3/c1-20(26,12-24)15-4-2-13(3-5-15)19(25)22-18-10-17-14(11-21-18)8-9-23(17)16-6-7-16/h2-5,8-11,16,24,26H,6-7,12H2,1H3,(H,21,22,25)/t20-/m0/s1
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n/an/a 69n/an/an/an/a7.525



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128393
PNG
(US8802695, 9)
Show SMILES CC(C)(O)c1ccc(cc1)C(=O)Nc1cc2n(CC3CC3)ccc2cn1
Show InChI InChI=1S/C21H23N3O2/c1-21(2,26)17-7-5-15(6-8-17)20(25)23-19-11-18-16(12-22-19)9-10-24(18)13-14-3-4-14/h5-12,14,26H,3-4,13H2,1-2H3,(H,22,23,25)
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UniChem

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n/an/a 81n/an/an/an/a7.525



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The test compounds (2.5 μL) dissolved in DMSO were added to wells containing 37.5 μL of the reaction solution (25 mM HEPES (pH 7.5), 10 mM ...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128409
PNG
(US8802695, 25)
Show SMILES Cn1c(Cl)c(Cl)c2cnc(NC(=O)c3ccc(cc3)C(C)(C)O)cc12
Show InChI InChI=1S/C18H17Cl2N3O2/c1-18(2,25)11-6-4-10(5-7-11)17(24)22-14-8-13-12(9-21-14)15(19)16(20)23(13)3/h4-9,25H,1-3H3,(H,21,22,24)
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n/an/a 146n/an/an/an/a7.325



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128401
PNG
(US8802695, 17)
Show SMILES C[C@](O)(CO)c1ccc(cc1)C(=O)Nc1cc2n(ccc2cn1)C1CC1
Show InChI InChI=1S/C20H21N3O3/c1-20(26,12-24)15-4-2-13(3-5-15)19(25)22-18-10-17-14(11-21-18)8-9-23(17)16-6-7-16/h2-5,8-11,16,24,26H,6-7,12H2,1H3,(H,21,22,25)/t20-/m0/s1
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n/an/a 214n/an/an/an/a7.325



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128393
PNG
(US8802695, 9)
Show SMILES CC(C)(O)c1ccc(cc1)C(=O)Nc1cc2n(CC3CC3)ccc2cn1
Show InChI InChI=1S/C21H23N3O2/c1-21(2,26)17-7-5-15(6-8-17)20(25)23-19-11-18-16(12-22-19)9-10-24(18)13-14-3-4-14/h5-12,14,26H,3-4,13H2,1-2H3,(H,22,23,25)
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n/an/a 237n/an/an/an/a7.325



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)


(Homo sapiens (Human))
BDBM128411
PNG
(US8802695, 27)
Show SMILES CCn1ccc2cnc(NC(=O)c3ccc(c(C)c3)[C@@](C)(O)CO)cc12
Show InChI InChI=1S/C20H23N3O3/c1-4-23-8-7-15-11-21-18(10-17(15)23)22-19(25)14-5-6-16(13(2)9-14)20(3,26)12-24/h5-11,24,26H,4,12H2,1-3H3,(H,21,22,25)/t20-/m0/s1
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n/an/a 528n/an/an/an/a7.325



Takeda Pharmaceutical Company Limited

US Patent


Assay Description
The inhibitory properties of compounds to ASK1 may be determined using a white 384-well-plate format under the following reaction conditions: 25 nM A...


US Patent US8802695 (2014)


BindingDB Entry DOI: 10.7270/Q27W69WD
More data for this
Ligand-Target Pair