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Found 200 Enz. Inhib. hit(s) with Target = 'Neuropeptide S receptor'
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataKi:  48nMAssay Description:Binding affinity to human NPSR by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443390(CHEMBL1474387)
Affinity DataIC50:  0.960nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322839(CHEMBL1210313 | N-(3-methyl-1-morpholinopentan-3-y...)
Affinity DataIC50:  1.20nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322839(CHEMBL1210313 | N-(3-methyl-1-morpholinopentan-3-y...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [125I]Tyr10-NPS from neuropeptide S receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443390(CHEMBL1474387)
Affinity DataIC50:  1.30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50417462(CHEMBL469696)
Affinity DataIC50:  2nMAssay Description:Antagonist activity at human recombinant GPR154 receptor expressed in HEK293 cells assessed as inhibition of neuropeptide S-induced increase of intra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443406(CHEMBL3086823)
Affinity DataIC50:  2.20nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443409(CHEMBL3086836)
Affinity DataIC50:  3.20nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443400(CHEMBL3086821)
Affinity DataIC50:  3.40nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443408(CHEMBL3086837)
Affinity DataIC50:  3.40nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443390(CHEMBL1474387)
Affinity DataIC50:  3.5nMAssay Description:Displacement of [125I]Tyr10-NPS from human neuropeptide S receptor expressed in CHO cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443405(CHEMBL3086824)
Affinity DataIC50:  4.5nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  5.30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443404(CHEMBL3086825)
Affinity DataIC50:  5.70nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443392(CHEMBL1472563)
Affinity DataIC50:  6.20nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322839(CHEMBL1210313 | N-(3-methyl-1-morpholinopentan-3-y...)
Affinity DataIC50:  6.70nMAssay Description:Displacement of [125I]Tyr10-NPS from human neuropeptide S receptor expressed in CHO cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322836(CHEMBL1210244 | rac-N-(3-methyl-1-(piperidin-1-yl)...)
Affinity DataIC50:  7nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443399(CHEMBL3086822)
Affinity DataIC50:  9nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443398(CHEMBL1514777)
Affinity DataIC50:  9.10nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443407(CHEMBL3086838)
Affinity DataIC50:  9.20nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human recombinant GPR154 receptor expressed in HEK293 cells assessed as inhibition of neuropeptide S-induced increase of intra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322839(CHEMBL1210313 | N-(3-methyl-1-morpholinopentan-3-y...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50331943(5-phenyl-2-(2-(piperidine-1-carbonyl)phenyl)-2,3-d...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322839(CHEMBL1210313 | N-(3-methyl-1-morpholinopentan-3-y...)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322839(CHEMBL1210313 | N-(3-methyl-1-morpholinopentan-3-y...)
Affinity DataIC50:  11nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443392(CHEMBL1472563)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443394(CHEMBL3086834)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322837(CHEMBL1210311 | rac-N-(1-(4-fluoropiperidin-1-yl)-...)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443393(CHEMBL1553073)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443396(CHEMBL3086833)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443395(CHEMBL1315807)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322842(CHEMBL1210177 | N-((1-methyl-2-oxo-1,2-dihydroquin...)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50417464(CHEMBL1289677)
Affinity DataIC50:  19.9nMAssay Description:Antagonist activity at human recombinant GPR154 receptor expressed in HEK293 cells assessed as inhibition of neuropeptide S-induced increase of intra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322838(CHEMBL1210312 | rac-N-(1-(4,4-difluoropiperidin-1-...)
Affinity DataIC50:  22nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322839(CHEMBL1210313 | N-(3-methyl-1-morpholinopentan-3-y...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322839(CHEMBL1210313 | N-(3-methyl-1-morpholinopentan-3-y...)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443403(CHEMBL3086826)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  25nMAssay Description:Displacement of [125I]Tyr10-NPS from human neuropeptide S receptor expressed in CHO cells after 1.5 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50417462(CHEMBL469696)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443417(CHEMBL3086828)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443391(CHEMBL469695)
Affinity DataIC50:  28nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM89034((1,2-dimethyl-3-imidazo[1,2-a]pyridin-4-iumyl)-dip...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced ERK activation after 20 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50322834(CHEMBL1210242 | N-((1-methyl-2-oxo-1,2-dihydroquin...)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50417463(CHEMBL1289571)
Affinity DataIC50:  31.6nMAssay Description:Antagonist activity at human recombinant GPR154 receptor expressed in HEK293 cells assessed as inhibition of neuropeptide S-induced increase of intra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443396(CHEMBL3086833)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50348617(CHEMBL1801361)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) assessed as intracellular calcium level by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50348617(CHEMBL1801361)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human recombinant NPS receptor expressed in CHOK1 cells assessed as inhibition of NPS-induced calcium mobilization by FLIPR as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443402(CHEMBL3086827)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as inhibition of NPS-induced calcium mobilization aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuropeptide S receptor(Homo sapiens (Human))
University Of Ferrara

Curated by ChEMBL
LigandPNGBDBM50443390(CHEMBL1474387)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at neuropeptide S receptor (unknown origin) expressed in CHO cells assessed as cAMP level after 30 mins by phosphate-buffered sal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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