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Found 85 Enz. Inhib. hit(s) with Target = 'Interleukin-8'
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291126(CHEMBL265735 | CHEMBL3856136 | Interleukin-8 inhib...)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291119(CHEMBL267510 | CHEMBL3856125 | Interleukin-8 inhib...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291124(CHEMBL3856133 | CHEMBL411572 | Interleukin-8 inhib...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291118(CHEMBL3856131 | CHEMBL438589 | Interleukin-8 inhib...)
Affinity DataKi:  6.00E+3nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291131(CHEMBL3856127 | CHEMBL413247 | Interleukin-8 inhib...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291125(CHEMBL3856135 | CHEMBL411548 | Interleukin-8 inhib...)
Affinity DataKi:  9.30E+3nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291120(CHEMBL3856128 | CHEMBL410171 | Interleukin-8 inhib...)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291122(CHEMBL3856126 | CHEMBL428324 | Interleukin-8 inhib...)
Affinity DataKi:  1.20E+4nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50213962(CHEMBL410765)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291128(CHEMBL267749 | CHEMBL3856129 | Interleukin-8 inhib...)
Affinity DataKi:  1.30E+4nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291130(CHEMBL3856130 | CHEMBL405300 | Interleukin-8 inhib...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291123(CHEMBL3856132 | CHEMBL410211 | Interleukin-8 inhib...)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291121(CHEMBL2370828 | CHEMBL3856124 | Interleukin-8 inhi...)
Affinity DataKi:  1.06E+5nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50291129(CHEMBL2370827 | CHEMBL3856134 | Interleukin-8 inhi...)
Affinity DataKi:  3.83E+5nMAssay Description:Inhibition of Interleukin-8 (IL-8)More data for this Ligand-Target Pair
In DepthDetails Article
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277687(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-me...)
Affinity DataIC50:  2.80nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277693(2-((2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3...)
Affinity DataIC50:  2.90nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277686(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)
Affinity DataIC50:  5.60nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277702(5-((2-(3-((4-((4-(3-(5-tert-Butyl)-2-methoxy-3-(me...)
Affinity DataIC50:  7.30nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277688(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)
Affinity DataIC50:  7.30nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataIC50:  8nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277682(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)
Affinity DataIC50:  8nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50295276(2-(2-(2-fluorophenylamino)phenyl)acetic acid | CHE...)
Affinity DataIC50:  9nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50295266(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanoic a...)
Affinity DataIC50:  10nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277694(US10072034, Example 20(a) | US10072034, Example 20...)
Affinity DataIC50:  10.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277683(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  11.7nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277685(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  11.7nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50295267(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}propanamide...)
Affinity DataIC50:  12nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50295281(2-(2-(2-fluorophenoxy)phenyl)acetic acid | CHEMBL2...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50295268(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(methyls...)
Affinity DataIC50:  13nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277696(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  14.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277701(5-((2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(m...)
Affinity DataIC50:  15.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277690(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(ethylsulf...)
Affinity DataIC50:  16.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277689(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-3-(ethylsulfo...)
Affinity DataIC50:  16.4nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277691(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl) isoxazol-3-y...)
Affinity DataIC50:  17.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277677(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy)-3...)
Affinity DataIC50:  17.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277680(2-(2-(2-(3-((4-((4-(3-(5-tert-Butyl-2-methoxy-3-(m...)
Affinity DataIC50:  18.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277697(1-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  18.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277694(US10072034, Example 20(a) | US10072034, Example 20...)
Affinity DataIC50:  19.1nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277679(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-(methoxy-d...)
Affinity DataIC50:  19.5nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50169048((R)-2-(3-Benzoyl-phenyl)-propionic acid | (R)-2-(3...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50295270(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N-(2-hydro...)
Affinity DataIC50:  20nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277703(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  20.6nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277681(2-(2-(2-(3-(4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(...)
Affinity DataIC50:  20.8nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277676(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-...)
Affinity DataIC50:  24.6nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50295269(2-{2-[(2,6-Dichlorophenyl)amino]phenyl}-N,N'-[3,3-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50090679(2-(2-(2,5-dichlorophenylamino)phenyl)acetic acid |...)
Affinity DataIC50:  25nMAssay Description:Inhibition of CXCL8-induced chemotaxis in human polymorphonuclear leukocyte pretreated for 15 mins measured after 4 hrs by cell migration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277700(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl-2-methoxy-3-(...)
Affinity DataIC50:  26.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277684(2-(2-(2-(3-((4-((4-(3-(5-(tert-Butyl)-3-(dimethylp...)
Affinity DataIC50:  26.5nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277698(N-(3-(3-(4-((2-((3-(2-(2-(1H-Tetrazol-5-yl)methoxy...)
Affinity DataIC50:  29.2nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInterleukin-8(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM277692(N-(5-(tert-Butl-2-methoxy-3-(3-(4-((2-((3-methoxy-...)
Affinity DataIC50:  29.3nMAssay Description:PBMCs from healthy subjects are separated from whole blood using a density gradient (Lymphoprep, Axis-Shield Healthcare). Cells are added to a 96 wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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