KEGG   Rattus norvegicus (rat): 140694
Entry
140694            CDS       T01003                                 
Symbol
Dnm1
Name
(RefSeq) dynamin-1
  KO
K01528  dynamin 1/3 [EC:3.6.5.5]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04072  Phospholipase D signaling pathway
rno04144  Endocytosis
rno04721  Synaptic vesicle cycle
rno04961  Endocrine and other factor-regulated calcium reabsorption
rno05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    140694 (Dnm1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    140694 (Dnm1)
 09150 Organismal Systems
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    140694 (Dnm1)
  09156 Nervous system
   04721 Synaptic vesicle cycle
    140694 (Dnm1)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    140694 (Dnm1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:rno04131]
    140694 (Dnm1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:rno04147]
    140694 (Dnm1)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.5  Acting on GTP to facilitate cellular and subcellular movement
    3.6.5.5  dynamin GTPase
     140694 (Dnm1)
Membrane trafficking [BR:rno04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Dynamin
    140694 (Dnm1)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    140694 (Dnm1)
   RhoA-dependent endocytosis
    140694 (Dnm1)
Exosome [BR:rno04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   140694 (Dnm1)
SSDB
Motif
Pfam: Dynamin_M Dynamin_N GED PH MMR_HSR1
Other DBs
NCBI-GeneID: 140694
NCBI-ProteinID: NP_542420
RGD: 71096
Ensembl: ENSRNOG00000033835
UniProt: P21575
Structure
Position
3:complement(36002535..36055220)
AA seq 851 aa
MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG
SGIVTRRPLVLQLVNSTTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI
NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD
LANSDALKIAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK
DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL
QSQLLSIEKEVDEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA
RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDLAFEATVKKQVQKL
KEPSIKCVDMVVSELTSTIRKCSEKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID
IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE
YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE
TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE
QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT
PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP
PGVPRITISDP
NT seq 2556 nt   +upstreamnt  +downstreamnt
atgggcaaccgcggcatggaagacctcatcccgctggttaaccggttacaggacgccttc
tctgccatcggccagaacgcggacctcgacttgccgcagatcgccgtggtaggcggccag
agcgccggcaagagctcggtgctggagaatttcgtgggcagggacttcttgccccgagga
tccggcatcgtcacccggcgtcccctggtcctgcagctggttaattctaccacagaatat
gccgagttcctgcactgcaaggggaagaaattcaccgacttcgaggaggtgcgcctggag
atcgaggctgagaccgaccgagtcactggcaccaacaagggcatttcgcctgtgcccatc
aacctgcgtgtctactcaccccatgtgctcaacctgactctagtggacctgccaggaatg
accaaggtcccagttggggaccaacctcctgacatcgagttccagatccgggacatgctt
atgcagtttgtcactaaggagaactgccttatcctggctgtgtcccctgccaactcggac
ctggccaactctgatgccctcaagatcgccaaggaggtggacccccagggtcagcgcacc
attggggtcatcaccaagttggacctgatggacgagggcacagatgctcgggatgtgctg
gagaacaagctgctcccattgcgcagaggctacattggcgtggtgaaccggagccagaag
gacatagatggcaagaaggatatcacagccgccttggctgccgagcgcaaattcttcctc
tcccacccatcctaccgccacttggctgaccgcatgggcacaccctacctgcagaaggtc
ctcaaccagcaactgaccaaccacatccgggacacgctgccgggacttcggaacaaactg
cagagccagctgctgtccattgagaaggaggtggacgagtacaagaacttccgaccggat
gacccagcgcgcaagaccaaggccctgctgcagatggtccagcagtttgcagtggacttc
gagaagcgcattgagggttctggagaccagatcgacacttatgaactgtcaggtggagcc
cgcattaaccggatcttccacgaacgcttcccttttgagctggttaagatggagtttgat
gagaaggaactgcgaagggagatcagctacgctatcaagaacattcatggcatcaggaca
ggcctcttcactcctgacctcgcttttgaagccacagtgaaaaagcaggtgcagaagctc
aaagagcccagtatcaagtgtgtggacatggtagtcagtgagctcacgtccaccatcaga
aagtgtagtgaaaagctccagcaatacccccgtctgcgggaggaaatggaacggattgtg
accacccacatccgagaacgtgagggccgcaccaaggagcaggtcatgcttctcatcgac
attgagttggcttacatgaataccaaccatgaagacttcataggctttgccaatgctcag
cagagaagcaaccagatgaacaagaagaagacttcagggaaccaggatgagattctggtc
attcgaaaggggtggctgaccatcaacaacatcggcatcatgaagggaggctccaaggag
tactggtttgtgttgactgctgagaatctgtcctggtacaaggacgatgaggagaaagag
aagaagtacatgctgtctgtggataatctgaagctgcgtgatgtggagaagggcttcatg
tcaagcaagcatatttttgccctcttcaacactgagcagaggaatgtctacaaggattac
cggcagctggaactggcctgtgagacacaggaggaggtggacagttggaaggcttccttt
ctgagggctggcgtgtaccctgagcgtgttggggacaaggagaaagccagtgagactgag
gagaacggctctgacagcttcatgcactccatggaccctcagctggagcgccaggtggag
accatccggaacctggtagactcgtacatggccattgtcaacaagactgtacgggatctc
atgcccaagaccatcatgcacctcatgatcaacaataccaaggagtttatcttctctgag
ctgctggccaacctgtactcttgcggggaccagaacacgctgatggaagaatcggccgaa
caggctcagcggcgcgacgagatgctgcgtatgtaccacgcactgaaggaggcgctcagc
attatcggcgacatcaacacgaccaccgtcagcacgcccatgcccccgcccgtggacgac
tcctggctgcaggtgcagagcgtaccggccggacgcaggtcgcccacgtccagccccacg
ccgcagcgccgagcccccgccgtgcccccagcccggcccgggtcgcggggccctgctcct
gggcctccgcctgctggatccgccctggggggggctccccccgtgccctccaggccgggg
gcttcccctgacccctttggcccccctccccaggtgccctcgcgccccaaccgcgccccg
cctggggtccccagaatcactatcagtgacccctga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   RGD (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (14)   
   RefSeq(nuc) (12)   
   GenBank (1)   
   EMBL (1)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (52)   

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