KEGG   Homo sapiens (human): 330
Entry
330               CDS       T01001                                 
Symbol
BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, IAP-1, MALT2, MIHC, RNF49, c-IAP2
Name
(RefSeq) baculoviral IAP repeat containing 3
  KO
K16060  baculoviral IAP repeat-containing protein 2/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa01524  Platinum drug resistance
hsa04064  NF-kappa B signaling pathway
hsa04120  Ubiquitin mediated proteolysis
hsa04210  Apoptosis
hsa04215  Apoptosis - multiple species
hsa04217  Necroptosis
hsa04390  Hippo signaling pathway
hsa04510  Focal adhesion
hsa04621  NOD-like receptor signaling pathway
hsa04668  TNF signaling pathway
hsa05132  Salmonella infection
hsa05145  Toxoplasmosis
hsa05168  Herpes simplex virus 1 infection
hsa05200  Pathways in cancer
hsa05202  Transcriptional misregulation in cancer
hsa05222  Small cell lung cancer
Network
nt06168  Herpes simplex virus 1 (HSV-1)
nt06240  Transcription (cancer)
nt06516  TNF signaling
  Element
N00123  Amplified REL to transcription
N00560  HSV gD to HVEM-NFKB signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    330 (BIRC3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    330 (BIRC3)
   04064 NF-kappa B signaling pathway
    330 (BIRC3)
   04668 TNF signaling pathway
    330 (BIRC3)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    330 (BIRC3)
   04215 Apoptosis - multiple species
    330 (BIRC3)
   04217 Necroptosis
    330 (BIRC3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    330 (BIRC3)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    330 (BIRC3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    330 (BIRC3)
   05202 Transcriptional misregulation in cancer
    330 (BIRC3)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    330 (BIRC3)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    330 (BIRC3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    330 (BIRC3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    330 (BIRC3)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    330 (BIRC3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    330 (BIRC3)
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    330 (BIRC3)
Peptidases and inhibitors [BR:hsa01002]
 Peptidase inhibitors
  Family I32: IAP family
   330 (BIRC3)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    330 (BIRC3)
SSDB
Motif
Pfam: BIR BIRC2-3-like_UBA CARD zf-C3HC4_3 Prok-RING_4 zf-RING_2 zf-RING_5 OTT_1508_deam DUF2039 zf-C3HC4_2
Other DBs
NCBI-GeneID: 330
NCBI-ProteinID: NP_001156
OMIM: 601721
HGNC: 591
Ensembl: ENSG00000023445
UniProt: Q13489
Structure
Position
11:102317484..102339403
AA seq 604 aa
MNIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGV
NDKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSVNNLEATSQPTFPSSVTNS
THSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWP
LTFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQ
DTSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLR
CWESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESS
IIHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDL
LNAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHD
VIKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVS
DLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVR
TFLS
NT seq 1815 nt   +upstreamnt  +downstreamnt
atgaacatagtagaaaacagcatattcttatcaaatttgatgaaaagcgccaacacgttt
gaactgaaatacgacttgtcatgtgaactgtaccgaatgtctacgtattccacttttcct
gctggggttcctgtctcagaaaggagtcttgctcgtgctggtttctattacactggtgtg
aatgacaaggtcaaatgcttctgttgtggcctgatgctggataactggaaaagaggagac
agtcctactgaaaagcataaaaagttgtatcctagctgcagattcgttcagagtctaaat
tccgttaacaacttggaagctacctctcagcctacttttccttcttcagtaacaaattcc
acacactcattacttccgggtacagaaaacagtggatatttccgtggctcttattcaaac
tctccatcaaatcctgtaaactccagagcaaatcaagatttttctgccttgatgagaagt
tcctaccactgtgcaatgaataacgaaaatgccagattacttacttttcagacatggcca
ttgacttttctgtcgccaacagatctggcaaaagcaggcttttactacataggacctgga
gacagagtggcttgctttgcctgtggtggaaaattgagcaattgggaaccgaaggataat
gctatgtcagaacacctgagacattttcccaaatgcccatttatagaaaatcagcttcaa
gacacttcaagatacacagtttctaatctgagcatgcagacacatgcagcccgctttaaa
acattctttaactggccctctagtgttctagttaatcctgagcagcttgcaagtgcgggt
ttttattatgtgggtaacagtgatgatgtcaaatgcttttgctgtgatggtggactcagg
tgttgggaatctggagatgatccatgggttcaacatgccaagtggtttccaaggtgtgag
tacttgataagaattaaaggacaggagttcatccgtcaagttcaagccagttaccctcat
ctacttgaacagctgctatccacatcagacagcccaggagatgaaaatgcagagtcatca
attatccattttgaacctggagaagaccattcagaagatgcaatcatgatgaatactcct
gtgattaatgctgccgtggaaatgggctttagtagaagcctggtaaaacagacagttcag
agaaaaatcctagcaactggagagaattatagactagtcaatgatcttgtgttagactta
ctcaatgcagaagatgaaataagggaagaggagagagaaagagcaactgaggaaaaagaa
tcaaatgatttattattaatccggaagaatagaatggcactttttcaacatttgacttgt
gtaattccaatcctggatagtctactaactgccggaattattaatgaacaagaacatgat
gttattaaacagaagacacagacgtctttacaagcaagagaactgattgatacgatttta
gtaaaaggaaatattgcagccactgtattcagaaactctctgcaagaagctgaagctgtg
ttatatgagcatttatttgtgcaacaggacataaaatatattcccacagaagatgtttca
gatctaccagtggaagaacaattgcggagactacaagaagaaagaacatgtaaagtgtgt
atggacaaagaagtgtccatagtgtttattccttgtggtcatctagtagtatgcaaagat
tgtgctccttctttaagaaagtgtcctatttgtaggagtacaatcaagggtacagttcgt
acatttctttcatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (16)   
   KEGG PATHWAY (16)   
Network (5)   
   KEGG NETWORK (5)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (47)   
   KEGG ORTHOLOGY (1)   
   RefGene (31)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (10)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (35)   
   RefSeq(nuc) (3)   
   GenBank (16)   
   EMBL (16)   
3D Structure (6)   
   PDB (6)   
Protein domain (10)   
   Pfam (10)   
All databases (129)   

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