1JCR: CRYSTAL STRUCTURE OF RAT PROTEIN FARNESYLTRANSFERASE COMPLEXED WITH THE NON-SUBSTRATE TETRAPEPTIDE INHIBITOR CVFM AND FARNESYL DIPHOSPHATE SUBSTRATE

PDB ID: 1JCRDownload
MMDB ID: 17595
PDB Deposition Date: 2001/6/11
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 1JCR: trimeric; determined by author and by software (PISA)
Molecular Components in 1JCR
Label Count Molecule
Proteins (3 molecules)
1
Protein Farnesyltransferase, Alpha Subunit
Molecule annotation
1
Protein Farnesyltransferase, Beta Subunit
Molecule annotation
1
Synthetic Tetrapeptide Cvfm
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
ACETIC ACIDACETIC ACID
2
1
ZINC IONZINC ION
3
1
FARNESYL DIPHOSPHATEFARNESYL DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303