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2F3E:
Crystal Structure Of The Bace Complex With Axq093, A Macrocyclic Inhibitor
PDB ID:
2F3E
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MMDB ID:
40827
PDB Deposition Date:
2005/11/21
Updated in MMDB:
2017/10
Experimental Method:
x-ray diffraction
Resolution:
2.11 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2F3E: monomeric; determined by author
Molecular Components in 2F3E
Label
Count
Molecule
Protein (1 molecule)
A
1
Beta-secretase 1
(Gene symbol:
BACE1
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
{(E)-(3r,6s,9r)-3-[(1s,3r)-3-((S)-1 -Butylcarbamoyl-2-Methyl-Propylcarb Amoyl)-1-Hydroxy-Butyl]-6-Methyl-5,8-Dioxo-1,11-Dithia-4,7-Diaza-Cyclo Pentadec-13-En-9-Yl}-Carbamic Acid Tert-Butyl Ester
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303