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3TD8:
Structural Analysis of Pneumocystis carinii Dihydrofolate Reductase Complex with NADPH and 2,4-diamino-5-methyl-6-[2'-(4-carboxy-1-pentynyl)-5'-methoxybenzyl]pyrido[2,3-d]pyrimidine
PDB ID:
3TD8
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MMDB ID:
98667
PDB Deposition Date:
2011/8/10
Updated in MMDB:
2013/11
Experimental Method:
x-ray diffraction
Resolution:
1.8 Å
Source Organism:
Pneumocystis carinii
Similar Structures:
VAST+
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Biological Unit for 3TD8: monomeric; determined by author and by software (PISA)
Molecular Components in 3TD8
Label
Count
Molecule
Protein (1 molecule)
A
1
Dihydrofolate Reductase
Chemicals and Non-standard biopolymers (2 molecules)
1
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
6-{2-[(2,4-diamino-5-methylpyrido[2,3-d]pyrimidin-6-yl)methyl]-4-methoxyphenyl}hex-5-ynoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303