NCBI
National Center for
Biotechnology Information
Search
3JVX:
Crystal structure of Bacillus anthracis dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-(3-(3,4,5-trimethoxyphenyl)prop-1-ynyl)-6-ethylpyrimidine (UCP120A)
PDB ID:
3JVX
Download
MMDB ID:
84793
PDB Deposition Date:
2009/9/17
Updated in MMDB:
2013/11
Experimental Method:
x-ray diffraction
Resolution:
2.25 Å
Source Organism:
Bacillus anthracis
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3JVX: dimeric; determined by author and by software (PISA)
Molecular Components in 3JVX
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
Dihydrofolate Reductase
Chemicals and Non-standard biopolymers (4 molecules)
1
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
6-ethyl-5-[3-(3,4,5-trimethoxyphenyl)prop-1-yn-1-yl]pyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303