3E30: Protein farnesyltransferase complexed with FPP and ethylene diamine inhibitor 4

PDB ID: 3E30Download
MMDB ID: 70115
PDB Deposition Date: 2008/8/6
Updated in MMDB: 2011/05
Experimental Method:
x-ray diffraction
Resolution: 2.45  Å
Source Organism:
Similar Structures:
Biological Unit for 3E30: monomeric; determined by author
Molecular Components in 3E30
Label Count Molecule
Protein (1 molecule)
1
Protein Farnesyltransferase/geranylgeranyltransferase Type-1 Subunit Alpha
(Gene symbol: Fnta)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
FARNESYL DIPHOSPHATEFARNESYL DIPHOSPHATE
2
1
tert-butyl 4-({(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)[(1-methyl-1H-imidazol-4-yl)sulfonyl]amino}methyl)piperidine-1-carboxylatetert-butyl 4-({(2-{(4-cyanophenyl)[(1-methyl-1H-imidazol-5-yl)methyl]amino}ethyl)[(1-methyl-1H-imidazol-4-yl)sulfonyl]amino}methyl)piperidine-1-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303