3FZM: Crystal Structures of Hsc70/Bag1 in Complex with Small Molecule Inhibitors

PDB ID: 3FZMDownload
MMDB ID: 70258
PDB Deposition Date: 2009/1/26
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 3FZM: dimeric; determined by author and by software (PISA)
Molecular Components in 3FZM
Label Count Molecule
Proteins (2 molecules)
1
Heat Shock Cognate 71 KDA Protein
(Gene symbol: HSPA8)
Molecule annotation
1
BAG Family Molecular Chaperone Regulator 1
(Gene symbol: BAG1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-[[(2R,3S,4R,5R)-5-[6-amino-8-(quinolin-6-ylmethylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitri le4-[[(2R,3S,4R,5R)-5-[6-amino-8-(quinolin-6-ylmethylamino)purin-9-yl]-3,4-dihydroxy-oxolan-2-yl]methoxymethyl]benzonitri le
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303