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3IDP:
B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor
PDB ID:
3IDP
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MMDB ID:
207704
PDB Deposition Date:
2009/7/21
Updated in MMDB:
2021/10
Experimental Method:
x-ray diffraction
Resolution:
2.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3IDP: monomeric; determined by author and by software (PISA)
Molecular Components in 3IDP
Label
Count
Molecule
Protein (1 molecule)
B
1
B-raf Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol:
BRAF
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
N~1~-(4-chlorophenyl)-6-methyl-N~5~-[3-(7H-purin-6-yl)pyridin-2-yl]isoquinoline-1,5-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303