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4A03:
Crystal Structure of Mycobacterium tuberculosis DXR in complex with the antibiotic FR900098 and cofactor NADPH
PDB ID:
4A03
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MMDB ID:
96600
PDB Deposition Date:
2011/9/7
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
1.65 Å
Source Organism:
Mycobacterium tuberculosis H37Rv
Similar Structures:
VAST+
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Biological Unit for 4A03: dimeric; determined by author and by software (PISA)
Molecular Components in 4A03
Label
Count
Molecule
Proteins (2 molecules)
A
B
2
1-deoxy-d-xylulose 5-phosphate Reductoisomerase
Chemicals and Non-standard biopolymers (7 molecules)
1
2
MANGANESE (II) ION
2
2
3-[ethanoyl(hydroxy)amino]propylphosphonic acid
3
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
4
1
GLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303