2G8J: Calpain 1 proteolytic core in complex with SNJ-1945, a alpha-ketoamide-type inhibitor

PDB ID: 2G8JDownload
MMDB ID: 39346
PDB Deposition Date: 2006/3/2
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 1.61  Å
Source Organism:
Similar Structures:
Biological Unit for 2G8J: monomeric; determined by author
Molecular Components in 2G8J
Label Count Molecule
Protein (1 molecule)
1
Calpain-1 Catalytic Subunit
(Gene symbol: Capn1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CALCIUM IONCALCIUM ION
2
1
((1S)-1-((((1S)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2,3-DIOXOPROPYL)AMINO)CARBONYL)-3-METHYLBUTYL)CARBAMIC ACID 5-METHOXY-3-OXAPENTYL ESTER((1S)-1-((((1S)-1-BENZYL-3-(CYCLOPROPYLAMINO)-2,3-DIOXOPROPYL)AMINO)CARBONYL)-3-METHYLBUTYL)CARBAMIC ACID 5-METHOXY-3-OXAPENTYL ESTER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303