3NDM: Crystal structure of Rho-Associated Protein Kinase (ROCK1) with a potent isoquinolone derivative

PDB ID: 3NDMDownload
MMDB ID: 87173
PDB Deposition Date: 2010/6/7
Updated in MMDB: 2010/12
Experimental Method:
x-ray diffraction
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 3NDM: dimeric; determined by author
Molecular Components in 3NDM
Label Count Molecule
Proteins (2 molecules)
2
Rho-associated Protein Kinase (Rock1)
(Gene symbol: ROCK1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(3S,4R)-N-(7-chloro-1-oxo-1,4-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamide(3S,4R)-N-(7-chloro-1-oxo-1,4-dihydroisoquinolin-6-yl)-4-(4-chlorophenyl)pyrrolidine-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303