2QPU: Sugar tongs mutant S378P in complex with acarbose

PDB ID: 2QPUDownload
MMDB ID: 65181
PDB Deposition Date: 2007/7/25
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 2QPU: monomeric; determined by author and by software (PISA)
Molecular Components in 2QPU
Label Count Molecule
Protein (1 molecule)
1
Alpha-amylase Type a Isozyme
(Gene symbol: LOC548204)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
1
beta-D-glucopyranosebeta-D-glucopyranose
2
1
alpha-D-glucopyranosealpha-D-glucopyranose
3
1
4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose
4
3
CALCIUM IONCALCIUM ION
5
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
2
1,5-anhydro-4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-methylcyclohexyl]amino}-alpha-D-glucopyranosyl)-D-glucitol1,5-anhydro-4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S,6R)-2,3,4,6-tetrahydroxy-5-methylcyclohexyl]amino}-alpha-D-glucopyranosyl)-D-glucitol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303