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3PTG:
Design and Synthesis of a Novel, Orally Efficacious Tri-substituted Thiophene Based JNK Inhibitor
PDB ID:
3PTG
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MMDB ID:
88977
PDB Deposition Date:
2010/12/2
Updated in MMDB:
2011/05
Experimental Method:
x-ray diffraction
Resolution:
2.43 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3PTG: dimeric; determined by author and by software (PISA)
Molecular Components in 3PTG
Label
Count
Molecule
Proteins (2 molecules)
A
1
Mitogen-activated Protein Kinase 10
(Gene symbol:
MAPK10
)
J
1
C-jun-amino-terminal Kinase-interacting Protein 1
(Gene symbol:
MAPK8IP1
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[4-methyl-3-(1H-1,2,4-triazol-5-yl)thiophen-2-yl]-2-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)acetamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303