3R01: The discovery of novel benzofuran-2-carboxylic acids as potent Pim-1 inhibitors

PDB ID: 3R01Download
MMDB ID: 90487
PDB Deposition Date: 2011/3/7
Updated in MMDB: 2011/05
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 3R01: monomeric; determined by author and by software (PISA)
Molecular Components in 3R01
Label Count Molecule
Protein (1 molecule)
1
Proto-oncogene Serine/threonine-protein Kinase Pim-1
(Gene symbol: PIM1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
IMIDAZOLEIMIDAZOLE
2
1
5-bromo-7-methoxy-1-benzofuran-2-carboxylic acid5-bromo-7-methoxy-1-benzofuran-2-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303