3BNZ: Crystal structure of Thymidylate Synthase ternary complex with dUMP and 8A inhibitor

PDB ID: 3BNZDownload
MMDB ID: 68535
PDB Deposition Date: 2007/12/15
Updated in MMDB: 2008/12
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 3BNZ: dimeric; determined by author and by software (PISA)
Molecular Components in 3BNZ
Label Count Molecule
Proteins (2 molecules)
2
Thymidylate Synthase
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
PHOSPHATE IONPHOSPHATE ION
2
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE2'-DEOXYURIDINE 5'-MONOPHOSPHATE
3
2
4-(4-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzonitrile4-(4-methyl-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)benzonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303