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2YM8:
Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors
PDB ID:
2YM8
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MMDB ID:
96290
PDB Deposition Date:
2011/6/6
Updated in MMDB:
2023/12
Experimental Method:
x-ray diffraction
Resolution:
2.07 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2YM8: monomeric; determined by author and by software (PISA)
Molecular Components in 2YM8
Label
Count
Molecule
Protein (1 molecule)
A
1
Serine/threonine-protein Kinase Chk1
(Gene symbol:
CHEK1
)
Chemicals and Non-standard biopolymers (10 molecules)
1
1
(R)-5-(8-CHLOROISOQUINOLIN-3-YLAMINO)-3-(1-(DIMETHYLAMINO)PROPAN-2-YLOXY)PYRAZINE-2-CARBONITRILE
2
9
1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303