3UXE: Design, Synthesis and Biological Evaluation of Potent Quinoline and Pyrroloquinoline Ammosamide Analogues as Inhibitors for Quinone Reductase 2

PDB ID: 3UXEDownload
MMDB ID: 96563
PDB Deposition Date: 2011/12/5
Updated in MMDB: 2022/12
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 3UXE: dimeric; determined by author and by software (PISA)
Molecular Components in 3UXE
Label Count Molecule
Proteins (2 molecules)
2
Ribosyldihydronicotinamide Dehydrogenase [quinone]
(Gene symbol: NQO2)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
2
ZINC ION (Link to PubChem not yet available)ZINC ION
2
2
FLAVIN-ADENINE DINUCLEOTIDE (Link to PubChem not yet available)FLAVIN-ADENINE DINUCLEOTIDE
3
2
8-amino-7-chloro-1-methyl-6-(methylideneamino)-2-oxo-1,2-dihydropyrrolo[4,3,2-de]quinoline-4-carboxamide (Link to PubChem not yet available)8-amino-7-chloro-1-methyl-6-(methylideneamino)-2-oxo-1,2-dihydropyrrolo[4,3,2-de]quinoline-4-carboxamide
4
1
GLYCEROL (Link to PubChem not yet available)GLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303