4DDL: Pde10a Crystal Structure Complexed With Novel Inhibitor

PDB ID: 4DDLDownload
MMDB ID: 98250
PDB Deposition Date: 2012/1/18
Updated in MMDB: 2012/03
Experimental Method:
x-ray diffraction
Resolution: 2.07  Å
Source Organism:
Similar Structures:
Biological Unit for 4DDL: trimeric; determined by software (PISA)
Molecular Components in 4DDL
Label Count Molecule
Proteins (3 molecules)
3
Camp and Camp-inhibited Cgmp 3',5'-cyclic Phosphodiesterase 10A
(Gene symbol: PDE10A)
Molecule annotation
Chemicals and Non-standard biopolymers (33 molecules)
1
6
Zinc IonZinc Ion
2
24
Sulfate IonSulfate Ion
3
3
2-{1-[5-(6,7-Dimethoxycinnolin-4-Yl)-3-Methylpyridin-2-Yl]piperidin-4-Yl}propan-2-Ol2-{1-[5-(6,7-Dimethoxycinnolin-4-Yl)-3-Methylpyridin-2-Yl]piperidin-4-Yl}propan-2-Ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303