4B0G: Complex of Aurora-A bound to an Imidazopyridine-based inhibitor

PDB ID: 4B0GDownload
MMDB ID: 108260
PDB Deposition Date: 2012/7/2
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 4B0G: monomeric; determined by author and by software (PISA)
Molecular Components in 4B0G
Label Count Molecule
Protein (1 molecule)
1
Aurora Kinase a
(Gene symbol: AURKA)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
6-bromo-2-(1-methyl-1H-imidazol-5-yl)-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1H-imidazo[4,5-b]pyridine6-bromo-2-(1-methyl-1H-imidazol-5-yl)-7-{4-[(5-methyl-1,2-oxazol-3-yl)methyl]piperazin-1-yl}-1H-imidazo[4,5-b]pyridine
2
4
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303