4F65: Crystal structure of Human Fibroblast Growth Factor Receptor 1 Kinase domain in complex with compound 8

PDB ID: 4F65Download
MMDB ID: 100408
PDB Deposition Date: 2012/5/14
Updated in MMDB: 2012/06
Experimental Method:
x-ray diffraction
Resolution: 2.26  Å
Source Organism:
Similar Structures:
Biological Unit for 4F65: dimeric; determined by author
Molecular Components in 4F65
Label Count Molecule
Proteins (2 molecules)
2
Fibroblast Growth Factor Receptor 1
(Gene symbol: FGFR1)
Molecule annotation
Chemicals and Non-standard biopolymers (16 molecules)
1
4
SULFATE IONSULFATE ION
2
10
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
2
5-bromo-N~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]-N~4~-[3-(2-phenylethyl)-1H-pyrazol-5-yl]pyrimidine-2,4-diamine5-bromo-N~2~-[(3-methyl-1,2-oxazol-5-yl)methyl]-N~4~-[3-(2-phenylethyl)-1H-pyrazol-5-yl]pyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303