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2C5Y:
DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN
PDB ID:
2C5Y
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MMDB ID:
38082
PDB Deposition Date:
2005/11/3
Updated in MMDB:
2007/10
Experimental Method:
x-ray diffraction
Resolution:
2.25 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 2C5Y: monomeric; determined by author and by software (PQS)
Molecular Components in 2C5Y
Label
Count
Molecule
Protein (1 molecule)
A
1
Cell Division Protein Kinase 2
(Gene symbol:
CDK2
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
HYDROXY(OXO)(3-{[(2Z)-4-[3-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]PYRIMIDIN-2(5H)-YLIDENE]AMINO}PHENYL)AMMONIUM
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303