Abstract
A series of potent P2-achiral, P'-extended alpha-ketoamide inhibitors of calpain I is described.
MeSH terms
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Amides / chemistry
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Amides / pharmacology*
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Calpain / antagonists & inhibitors*
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Humans
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Protease Inhibitors / chemistry
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Protease Inhibitors / pharmacology*
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Recombinant Proteins / antagonists & inhibitors
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Stereoisomerism
Substances
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Amides
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Protease Inhibitors
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Recombinant Proteins
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Calpain