New chlorinated diphenyl ethers from an Aspergillus species

J Nat Prod. 2002 Jan;65(1):7-10. doi: 10.1021/np0102758.

Abstract

Two new chlorinated diphenyl ethers (5, 6) have been isolated from the culture broth of an Aspergillus species obtained from leaf litter, together with the known benzophenone sulochrin (1), the grisandiene geodin (2), and the diphenyl ether asterric acid (3). The structure of another metabolite, methyl asterrate (4), was confirmed by single-crystal X-ray structure analysis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / chemistry
  • Antifungal Agents / isolation & purification*
  • Antifungal Agents / pharmacology
  • Antinematodal Agents / chemistry
  • Antinematodal Agents / isolation & purification*
  • Antinematodal Agents / pharmacology
  • Aspergillus / chemistry*
  • Aspergillus / enzymology
  • Australia
  • Benzoates / chemistry
  • Benzoates / isolation & purification
  • Benzoates / pharmacology
  • Benzofurans / chemistry
  • Benzofurans / isolation & purification
  • Benzofurans / pharmacology
  • Chromatography
  • Crystallography, X-Ray
  • Nuclear Magnetic Resonance, Biomolecular
  • Oxygenases / analysis
  • Oxygenases / metabolism
  • Phenols / chemistry
  • Phenols / isolation & purification
  • Phenols / pharmacology
  • Phenyl Ethers / chemistry
  • Phenyl Ethers / isolation & purification*
  • Phenyl Ethers / pharmacology

Substances

  • Antifungal Agents
  • Antinematodal Agents
  • Benzoates
  • Benzofurans
  • Phenols
  • Phenyl Ethers
  • methyl asterrate
  • methyl chloroasterrate
  • methyl dichloroasterrate
  • geodin
  • asterric acid
  • sulochrin
  • Oxygenases
  • ligninase