Your request to link to rcsb for Cyclin-A2
- 1E9H: thr 160 phosphorylated cdk2 - human cyclin a3 complex with the inhibitor indirubin-5-sulphonate bound (10.1016/S0969-2126(01)00598-6 )
- 1FIN: cyclin a-cyclin-dependent kinase 2 complex (10.1038/376313A0 )
- 1FVV: the structure of cdk2/cyclin a in complex with an oxindole inhibitor (10.1126/SCIENCE.291.5501.134 )
- 1GY3: pcdk2/cyclin a in complex with mgadp, nitrate and peptide substrate (10.1021/BI0201724 )
- 1H1P: structure of human thr160-phospho cdk2/cyclin a complexed with the inhibitor nu2058 (10.1038/NSB842 )
- 1H1Q: structure of human thr160-phospho cdk2/cyclin a complexed with the inhibitor nu6094 (10.1038/NSB842 )
- 1H1R: structure of human thr160-phospho cdk2/cyclin a complexed with the inhibitor nu6086 (10.1038/NSB842 )
- 1H1S: structure of human thr160-phospho cdk2/cyclin a complexed with the inhibitor nu6102 (10.1038/NSB842 )
- 1H24: cdk2/cyclin a in complex with a 9 residue recruitment peptide from e2f (10.1021/BI0268910 )
- 1H25: cdk2/cyclin a in complex with an 11-residue recruitment peptide from retinoblastoma-associated protein (10.1021/BI0268910 )
- 1H26: cdk2/cyclin a in complex with an 11-residue recruitment peptide from p53 (10.1021/BI0268910 )
- 1H27: cdk2/cyclin a in complex with an 11-residue recruitment peptide from p27 (10.1021/BI0268910 )
- 1H28: cdk2/cyclin a in complex with an 11-residue recruitment peptide from p107 (10.1021/BI0268910 )
- 1JST: phosphorylated cyclin-dependent kinase-2 bound to cyclin a (10.1038/NSB0896-696 )
- 1JSU: p27(kip1)/cyclin a/cdk2 complex (10.1038/382325A0 )
- 1OGU: structure of human thr160-phospho cdk2/cyclin a complexed with a 2-arylamino-4-cyclohexylmethyl-5-nitroso-6-aminopyrimidine inhibitor (10.1016/S0960-894X(03)00651-6 )
- 1OI9: structure of human thr160-phospho cdk2/cyclin a complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor (10.1021/JM0311442 )
- 1OIU: structure of human thr160-phospho cdk2/cyclin a complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor (10.1021/JM0311442 )
- 1OIY: structure of human thr160-phospho cdk2/cyclin a complexed with a 6-cyclohexylmethyloxy-2-anilino-purine inhibitor (10.1021/JM0311442 )
- 1OKV: cyclin a binding groove inhibitor h-arg-arg-leu-ile-phe-nh2 (10.1016/J.STR.2003.11.006 )
- 1OKW: cyclin a binding groove inhibitor ac-arg-arg-leu-asn-(m-cl-phe)-nh2 (10.1016/J.STR.2003.11.006 )
- 1OL1: cyclin a binding groove inhibitor h-cit-cit-leu-ile-(p-f-phe)-nh2 (10.1016/J.STR.2003.11.006 )
- 1OL2: cyclin a binding groove inhibitor h-arg-arg-leu-asn-(p-f-phe)-nh2 (10.1016/J.STR.2003.11.006 )
- 1P5E: the structure of phospho-cdk2/cyclin a in complex with the inhibitor 4,5,6,7-tetrabromobenzotriazole (tbs) (10.1046/J.1432-1033.2003.03697.X )
- 1PKD: the crystal structure of ucn-01 in complex with phospho-cdk2/cyclin a
- 1QMZ: phosphorylated cdk2-cyclyin a-substrate peptide complex (10.1038/15674 )
- 1URC: cyclin a binding groove inhibitor ace-arg-lys-leu-phe-gly (10.1039/B409157D )
- 1VIN: bovine cyclin a3 (10.1016/S0969-2126(01)00259-3 )
- 1VYW: structure of cdk2/cyclin a with pnu-292137 (10.1021/JM031145U )
- 2BKZ: structure of cdk2-cyclin a with pha-404611 (10.1016/J.BMCL.2005.01.023 )
- 2BPM: structure of cdk2-cyclin a with pha-630529 (10.1021/JM0408870 )
- 2C4G: structure of cdk2-cyclin a with pha-533514 (10.1016/J.BMCL.2005.10.071 )
- 2C5N: differential binding of inhibitors to active and inactive cdk2 provides insights for drug design (10.1016/J.CHEMBIOL.2005.11.011 )
- 2C5O: differential binding of inhibitors to active and inactive cdk2 provides insights for drug design (10.1016/J.CHEMBIOL.2005.11.011 )
- 2C5V: differential binding of inhibitors to active and inactive cdk2 provides insights for drug design (10.1016/J.CHEMBIOL.2005.11.011 )
- 2C5X: differential binding of inhibitors to active and inactive cdk2 provides insights for drug design (10.1016/J.CHEMBIOL.2005.11.011 )
- 2C6T: crystal structure of the human cdk2 complexed with the triazolopyrimidine inhibitor (10.1016/J.BMCL.2005.11.048 )
- 2CCH: the crystal structure of cdk2 cyclin a in complex with a substrate peptide derived from cdc modified with a gamma-linked atp analogue (10.1074/JBC.M600480200 )
- 2CCI: crystal structure of phospho-cdk2 cyclin a in complex with a peptide containing both the substrate and recruitment sites of cdc6 (10.1074/JBC.M600480200 )
- 2CJM: mechanism of cdk inhibition by active site phosphorylation: cdk2 y15p t160p in complex with cyclin a structure (10.1074/JBC.M609151200 )
- 2G9X: structure of thr 160 phosphorylated cdk2/cyclin a in complex with the inhibitor nu6271 (10.1021/JA060595J )
- 2I40: cdk2/cyclin a complexed with a thiophene carboxamide inhibitor (10.1016/J.BMCL.2006.09.018 )
- 2IW6: structure of human thr160-phospho cdk2-cyclin a complexed with a bisanilinopyrimidine inhibitor (10.1021/JM060216X )
- 2IW8: structure of human thr160-phospho cdk2-cyclin a f82h-l83v- h84d mutant with an o6-cyclohexylmethylguanine inhibitor (10.1021/JM060216X )
- 2IW9: structure of human thr160-phospho cdk2-cyclin a complexed with a bisanilinopyrimidine inhibitor (10.1021/JM060216X )
- 2UUE: replace: a strategy for iterative design of cyclin binding groove inhibitors (10.1002/CBIC.200600189 )
- 2UZB: crystal structure of human cdk2 complexed with a thiazolidinone inhibitor (10.1016/J.BMCL.2007.04.110 )
- 2UZD: crystal structure of human cdk2 complexed with a thiazolidinone inhibitor (10.1016/J.BMCL.2007.04.110 )
- 2UZE: crystal structure of human cdk2 complexed with a thiazolidinone inhibitor (10.1016/J.BMCL.2007.04.110 )
- 2UZL: crystal structure of human cdk2 complexed with a thiazolidinone inhibitor (10.1016/J.BMCL.2007.04.110 )
- 2V22: replace: a strategy for iterative design of cyclin binding groove inhibitors (10.1002/CBIC.200600189 )
- 2WEV: truncation and optimisation of peptide inhibitors of cdk2, cyclin a through structure guided design (10.1002/CMDC.200900093 )
- 2WFY: truncation and optimisation of peptide inhibitors of cdk2, cyclin a through structure guided design (10.1002/CMDC.200900093 )
- 2WHB: truncation and optimisation of peptide inhibitors of cdk2, cyclin a through structure guided design (10.1002/CMDC.200900093 )
- 2WIH: structure of cdk2-cyclin a with pha-848125 (10.1021/JM9006559 )
- 2WIP: structure of cdk2-cyclin a complexed with 8-anilino-1-methyl-4,5- dihydro- 1h-pyrazolo[4,3-h] quinazoline-3-carboxylic acid (10.1021/JM9006559 )
- 2WMA: structural and thermodynamic consequences of cyclization of peptide ligands for the recruitment site of cyclin a
- 2WMB: structural and thermodynamic consequences of cyclization of peptide ligands for the recruitment site of cyclin a
- 2WPA: optimisation of 6,6-dimethyl pyrrolo 3,4-c pyrazoles: identification of pha-793887, a potent cdk inhibitor suitable for intravenous dosing (10.1016/J.BMC.2010.01.042 )
- 2WXV: structure of cdk2-cyclin a with a pyrazolo(4,3-h) quinazoline-3- carboxamide inhibitor (10.1021/JM901710H )
- 2X1N: truncation and optimisation of peptide inhibitors of cdk2, cyclin a through structure guided design (10.1021/JM901660C )
- 3BHT: structure of phosphorylated thr160 cdk2/cyclin a in complex with the inhibitor meriolin 3 (10.1158/0008-5472.CAN-07-1826 )
- 3BHU: structure of phosphorylated thr160 cdk2/cyclin a in complex with the inhibitor meriolin 5 (10.1158/0008-5472.CAN-07-1826 )
- 3BHV: structure of phosphorylated thr160 cdk2/cyclin a in complex with the inhibitor variolin b (10.1158/0008-5472.CAN-07-1826 )
- 3DDP: structure of phosphorylated thr160 cdk2/cyclin a in complex with the inhibitor cr8 (10.1038/ONC.2008.191 )
- 3DDQ: structure of phosphorylated thr160 cdk2/cyclin a in complex with the inhibitor roscovitine (10.1038/ONC.2008.191 )
- 3DOG: structure of thr 160 phosphorylated cdk2/cyclin a in complex with the inhibitor n-&-n1 (10.1158/1535-7163.MCT-08-0080 )
- 3EID: cdk2/cyclina complexed with a pyrazolopyridazine inhibitor (10.1016/J.BMCL.2008.09.069 )
- 3EJ1: cdk2/cyclina complexed with a pyrazolopyridazine inhibitor (10.1016/J.BMCL.2008.09.069 )
- 3EOC: cdk2/cyclina complexed with a imidazo triazin-2-amine (10.1016/J.BMCL.2008.09.100 )
- 3F5X: cdk-2-cyclin complex with indazole inhibitor 9 bound at its active site (10.1016/J.BMCL.2008.11.105 )
- 3MY5: cdk2/cyclina in complex with drb (10.1016/J.CHEMBIOL.2010.07.012 )
- 3QHR: structure of a pcdk2/cyclina transition-state mimic (10.1016/J.STR.2011.02.016 )
- 3QHW: structure of a pcdk2/cyclina transition-state mimic (10.1016/J.STR.2011.02.016 )
- 3TNW: structure of cdk2/cyclin a in complex with can508 (10.1021/CB2004516 )
- 4BCK: structure of cdk2 in complex with cyclin a and a 2-amino-4- heteroaryl-pyrimidine inhibitor (10.1021/JM301495V )
- 4BCM: structure of cdk2 in complex with cyclin a and a 2-amino-4- heteroaryl-pyrimidine inhibitor (10.1021/JM301495V )
- 4BCN: structure of cdk2 in complex with cyclin a and a 2-amino-4- heteroaryl-pyrimidine inhibitor (10.1021/JM301495V )
- 4BCO: structure of cdk2 in complex with cyclin a and a 2-amino-4- heteroaryl-pyrimidine inhibitor (10.1021/JM301495V )
- 4BCP: structure of cdk2 in complex with cyclin a and a 2-amino-4- heteroaryl-pyrimidine inhibitor (10.1021/JM301475F )
- 4BCQ: structure of cdk2 in complex with cyclin a and a 2-amino-4- heteroaryl-pyrimidine inhibitor (10.1021/JM301495V )
- 4CFM: structure-based design of c8-substituted o6- cyclohexylmethoxyguanine cdk1 and 2 inhibitors. (10.1021/JM401555V )
- 4CFN: structure-based design of c8-substituted o6-cyclohexylmethoxyguanine cdk1 and 2 inhibitors. (10.1021/JM401555V )
- 4CFU: structure-based design of c8-substituted o6- cyclohexylmethoxyguanine cdk1 and 2 inhibitors. (10.1021/JM401555V )
- 4CFV: structure-based design of c8-substituted o6- cyclohexylmethoxyguanine cdk1 and 2 inhibitors. (10.1021/JM401555V )
- 4CFW: structure-based design of c8-substituted o6- cyclohexylmethoxyguanine cdk1 and 2 inhibitors. (10.1021/JM401555V )
- 4CFX: structure-based design of c8-substituted o6-cyclohexylmethoxyguanine cdk1 and 2 inhibitors. (10.1021/JM401555V )
- 4EOI: thr 160 phosphorylated cdk2 k89d, q131e - human cyclin a3 complex with the inhibitor ro3306 (10.1016/J.CHEMBIOL.2012.06.015 )
- 4EOJ: thr 160 phosphorylated cdk2 h84s, q85m, k89d - human cyclin a3 complex with atp (10.1016/J.CHEMBIOL.2012.06.015 )
- 4EOK: thr 160 phosphorylated cdk2 h84s, q85m, k89d - human cyclin a3 complex with the inhibitor nu6102 (10.1016/J.CHEMBIOL.2012.06.015 )
- 4EOL: thr 160 phosphorylated cdk2 h84s, q85m, k89d - human cyclin a3 complex with the inhibitor ro3306 (10.1016/J.CHEMBIOL.2012.06.015 )
- 4EOM: thr 160 phosphorylated cdk2 h84s, q85m, q131e - human cyclin a3 complex with atp (10.1016/J.CHEMBIOL.2012.06.015 )
- 4EON: thr 160 phosphorylated cdk2 h84s, q85m, q131e - human cyclin a3 complex with the inhibitor ro3306 (10.1016/J.CHEMBIOL.2012.06.015 )
- 4EOO: thr 160 phosphorylated cdk2 q131e - human cyclin a3 complex with atp (10.1016/J.CHEMBIOL.2012.06.015 )
- 4EOP: thr 160 phosphorylated cdk2 q131e - human cyclin a3 complex with the inhibitor ro3306 (10.1016/J.CHEMBIOL.2012.06.015 )
- 4EOQ: thr 160 phosphorylated cdk2 wt - human cyclin a3 complex with atp (10.1016/J.CHEMBIOL.2012.06.015 )
- 4EOR: thr 160 phosphorylated cdk2 wt - human cyclin a3 complex with the inhibitor nu6102 (10.1016/J.CHEMBIOL.2012.06.015 )
- 4EOS: thr 160 phosphorylated cdk2 wt - human cyclin a3 complex with the inhibitor ro3306 (10.1016/J.CHEMBIOL.2012.06.015 )
- 4FX3: crystal structure of the cdk2/cyclin a complex with oxindole inhibitor
- 4I3Z: structure of pcdk2/cyclina bound to adp and 2 magnesium ions
- 4II5: structure of pcdk2/cyclina bound to adp and 1 magnesium ion
- 5CYI: cdk2/cyclin a covalent complex with 6-(cyclohexylmethoxy)-n-(4- (vinylsulfonyl)phenyl)-9h-purin-2-amine (nu6300) (10.1016/J.CHEMBIOL.2015.07.018 )
- 5IF1: crystal structure apo cdk2/cyclin a (10.1021/ACSCHEMBIO.6B00074 )
- 5LMK: structure of phopsho-cdk2-cyclin a in complex with an atp-competitive inhibitor (10.1016/J.EJMECH.2016.12.023 )
- 5NEV: cdk2/cyclin a in complex with compound 73 (10.1021/ACS.JMEDCHEM.6B01254 )
- 6ATH: cdk2/cyclin a/p27-kid-deltac (10.1038/S41467-019-09446-W )
- 6GUB: cdk2/cyclina in complex with flavopiridol (10.1016/J.CHEMBIOL.2018.10.015 )
- 6GUC: cdk2/cyclina in complex with su9516 (10.1016/J.CHEMBIOL.2018.10.015 )
- 6GUE: cdk2/cyclina in complex with azd5438 (10.1016/J.CHEMBIOL.2018.10.015 )
- 6GUF: cdk2/cyclina in complex with cgp74514a (10.1016/J.CHEMBIOL.2018.10.015 )
- 6GVA: cdk2/cyclin a2 in complex with pyrazolo[4,3-d]pyrimidine inhibitor lgr4455 (10.1021/ACS.JMEDCHEM.9B00189 )
- 6P3W: crystal structure of the cyclin a-cdk2-orc1 complex (10.1002/PRO.3689 )
- 6RIJ: cdk2/cyclin a2 in complex with open-ring 5-nitrosopyrimidine inhibitor lc436