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• 4NPT: crystal structure of hiv-1 protease multiple mutant p51 complexed with darunavir (10.1021/CB4008875 )
• 4DQH: crystal structure of (r14c/e65c) hiv-1 protease in complex with drv (10.1021/JA2095766 )
• 4DQE: crystal structure of (g16c/l38c) hiv-1 protease in complex with drv (10.1021/JA2095766 )
• 5E5J: joint x-ray/neutron structure of hiv-1 protease triple mutant (v32i, i47v,v82i) with darunavir at ph 6.0 (10.1002/ANIE.201509989 )
• 3JW2: hiv-1 protease mutant g86s with darunavir (10.1002/PROT.22625 )
• 6OPU: hiv-1 protease nl4-3 k45i, m46i, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OPX: hiv-1 protease nl4-3 i13v, g16e, v32i, l33f, k45i, m46i, l76v, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 2HS2: crystal structure of m46l mutant of hiv-1 protease complexed with tmc114 (darunavir) (10.1016/J.JMB.2006.08.007 )
• 2HS1: ultra-high resolution x-ray crystal structure of hiv-1 protease v32i mutant with tmc114 (darunavir) inhibitor (10.1016/J.JMB.2006.08.007 )
• 2IDW: crystal structure analysis of hiv-1 protease mutant v82a with a potent non-peptide inhibitor (uic-94017) (10.1016/J.JMB.2004.02.052 )
• 4DQB: crystal structure of wild-type hiv-1 protease in complex with drv (10.1021/JA2095766 )
• 3LZS: crystal structure of hiv-1 crf01_ae protease in complex with darunavir (10.1128/JVI.00505-10 )
• 3LZV: structure of nelfinavir-resistant hiv-1 protease (d30n/n88d) in complex with darunavir. (10.1128/JVI.00505-10 )
• 3S54: hiv-1 protease triple mutants v32i, i47v, v82i with antiviral drug darunavir in space group p21212 (10.1002/PRO.2019 )
• 3S53: hiv-1 protease triple mutants v32i, i47v, v82i with antiviral drug darunavir in space group p212121 (10.1002/PRO.2019 )
• 3TKW: crystal structure of hiv protease model precursor/darunavir complex (10.1021/BI201809S )
• 3EBZ: high resolution hiv-2 protease structure in complex with clinical drug darunavir (10.1016/J.JMB.2008.09.031 )
• 6OPV: hiv-1 protease nl4-3 i13v, g16e, v32i, l33f, k45i, m46i, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OPY: hiv-1 protease nl4-3 i13v, g16e, v32i, l33f, k45i, m46i, a71v, l76v, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 3CYW: effect of flap mutations on structure of hiv-1 protease and inhibition by saquinavir and darunavir (10.1016/J.JMB.2008.05.062 )
• 6DH0: crystal structure of hiv-1 protease nl4-3 i84v mutant in complex with darunavir (10.1021/ACSINFECDIS.8B00336 )
• 2IEN: crystal structure analysis of hiv-1 protease with a potent non-peptide inhibitor (uic-94017) (10.1016/J.JMB.2004.02.052 )
• 2IEO: crystal structure analysis of hiv-1 protease mutant i84v with a potent non-peptide inhibitor (uic-94017) (10.1016/J.JMB.2004.02.052 )
• 6OPS: hiv-1 protease nl4-3 wt in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6OPW: hiv-1 protease nl4-3 i13v, g16e, v32i, l33f, k45i, m46i, a71v, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 3GGU: hiv pr drug resistant patient's variant in complex with darunavir (10.1128/JVI.00451-09 )
• 3U7S: hiv pr drug resistant patient's variant in complex with darunavir (10.1128/JVI.00451-09 )
• 4Q1W: mutations outside the active site of hiv-1 protease alter enzyme structure and dynamic ensemble of the active site to confer drug resistance (10.1021/JA504096M )
• 6DH3: crystal structure of hiv-1 protease nl4-3 v82i mutant in complex with darunavir (10.1021/ACSINFECDIS.8B00336 )
• 6DH6: crystal structure of hiv-1 protease nl4-3 i50v mutant in complex with darunavir (10.1021/ACSINFECDIS.8B00336 )
• 3PWM: hiv-1 protease mutant l76v with darunavir (10.1021/BI200033Z )
• 4LL3: structure of wild-type hiv protease in complex with darunavir (10.1111/FEBS.12743 )
• 5T2Z: crystal structure of multi-drug resistant hiv-1 protease pr-s17 in complex with darunavir (10.1371/JOURNAL.PONE.0168616 )
• 4HLA: crystal structure of wild type hiv-1 protease in complex with darunavir (10.1128/AAC.00868-13 )
• 3OXW: crystal structure of hiv-1 i50v, a71v protease in complex with the protease inhibitor darunavir (10.1128/JVI.03486-12 )
• 1T3R: hiv protease wild-type in complex with tmc114 inhibitor (10.1021/JM049560P )
• 3EKT: crystal structure of the inhibitor darunavir (drv) in complex with a multi-drug resistant hiv-1 protease variant (l10f/g48v/i54v/v64i/v82a) (refer: flap+ in citation.) (10.1021/CB300191K )
• 4DQF: crystal structure of (g16a/l38a) hiv-1 protease in complex with drv (10.1021/JA2095766 )
• 4DQC: crystal structure of (g16c/l38c) hiv-1 protease in complex with drv (10.1021/JA2095766 )
• 2F80: hiv-1 protease mutant d30n complexed with inhibitor tmc114 (10.1021/JM050943C )
• 2F81: hiv-1 protease mutant l90m complexed with inhibitor tmc114 (10.1021/JM050943C )
• 4YOA: crsystal structure hiv-1 protease mdr769 l33f complexed with darunavir (10.1016/J.BBREP.2015.06.003 )
• 6OPT: hiv-1 protease nl4-3 v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 3MWS: crystal structure of group n hiv-1 protease (10.1002/PRO.486 )
• 4NJT: crystal structure of multidrug-resistant clinical isolate a02 hiv-1 protease in complex with darunavir (10.1128/AAC.00107-14 )
• 3EM6: crystal structure of i50l/a71v mutant of hiv-1 protease in complex with inhibitor darunavir
• 3UCB: crystal structure of multidrug resistant hiv-1 protease clinical isolate pr20 in complex with darunavir (10.1021/BI2018317 )
• 3OGP: crystal structure of 6s-98s fiv protease with darunavir bound (10.1107/S0907444911011681 )
• 6OPZ: hiv-1 protease nl4-3 i13v, g16e, v32i, l33f, k45i, m46i, i54l, a71v, l76v, v82f, i84v mutant in complex with darunavir (10.1021/ACSCHEMBIO.9B00370 )
• 6DGX: crystal structure of hiv-1 protease nl4-3 wt in complex with darunavir (10.1021/ACSINFECDIS.8B00336 )
• 3D1Z: crystal structure of hiv-1 mutant i54m and inhibitor darunavir (10.1016/J.JMB.2008.05.062 )
• 5KR1: protease pr5-drv (10.1074/JBC.M116.747568 )
• 4Q1X: mutations outside the active site of hiv-1 protease alter enzyme structure and dynamic ensemble of the active site to confer drug resistance (10.1021/JA504096M )
• 4Q1Y: mutations outside the active site of hiv-1 protease alter enzyme structure and dynamic ensemble of the active site to confer drug resistance (10.1021/JA504096M )
• 3T3C: structure of hiv pr resistant patient derived mutant (comprising 22 mutations) in complex with drv (10.1128/AAC.00465-12 )
• 6OOT: hiv-1 protease nl4-3 l89v, l90m mutant in complex with darunavir (10.1021/ACS.BIOCHEM.9B00446 )
• 6OOU: crystal structure of hiv-1 protease nl4-3 l89v mutant in complex with darunavir (10.1021/ACS.BIOCHEM.9B00446 )
• 6OOS: hiv-1 protease nl4-3 l90m mutant in complex with darunavir (10.1021/ACS.BIOCHEM.9B00446 )
• 3JVY: hiv-1 protease mutant g86a with darunavir (10.1002/PROT.22625 )
• 3TTP: structure of multiresistant hiv-1 protease in complex with darunavir (10.1111/FEBS.12743 )
• 3D20: crystal structure of hiv-1 mutant i54v and inhibitor darunavia (10.1016/J.JMB.2008.05.062 )
• 3SO9: darunavir in complex with a human immunodeficiency virus type 1 protease variant (10.1016/J.BBRC.2011.08.045 )
• 5KQY: protease e35d-drv (10.1074/JBC.M116.747568 )
• 3LZU: crystal structure of a nelfinavir resistant hiv-1 crf01_ae protease variant (n88s) in complex with the protease inhibitor darunavir. (10.1128/JVI.00505-10 )
• 3BVB: cystal structure of hiv-1 active site mutant d25n and inhibitor darunavir (10.1074/JBC.M708506200 )
• 3OY4: crystal structure of hiv-1 l76v protease in complex with the protease inhibitor darunavir.
• 1T7I: the structural and thermodynamic basis for the binding of tmc114, a next-generation hiv-1 protease inhibitor. (10.1021/JM049560P )
• 2F8G: hiv-1 protease mutant i50v complexed with inhibitor tmc114 (10.1021/JM050943C )
• 5E5K: joint x-ray/neutron structure of hiv-1 protease triple mutant (v32i, i47v,v82i) with darunavir at ph 4.3 (10.1002/ANIE.201509989 )