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Found 97 with Last Name = 'abruzzo' and Initial = 'g'
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of wild type Candida albicans MY1055 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289910(1N-[21-(2-aminoethoxy)-3-(3-amino-1-hydroxypropyl)...)
Affinity DataIC50:  1nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289923(1N-[21-(2-aminoethoxy)-3-[3-(1,4-diaminobutylcarbo...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50491848(CHEMBL2387201)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of wild type Candida albicans MY1055 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499796(CHEMBL3742110)
Affinity DataIC50:  2.99nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289914(1N-[21-(2-aminoethoxy)-3-[3-(1,5-diaminopentylcarb...)
Affinity DataIC50:  3nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289922(1N-[3-[3-(1,4-diaminobutylcarboxamido)-1-hydroxypr...)
Affinity DataIC50:  3nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499806(CHEMBL3740011)
Affinity DataIC50:  3.05nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289924(1N-[21-(2-aminoethoxy)-3-[3-(1,2-diaminoethylcarbo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50491849(CHEMBL2387202)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of wild type Candida albicans 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285488(1N-[23-[1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-20...)
Affinity DataIC50:  5nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289917(1N-[21-(2-aminoethoxy)-3-[3-(1,3-diaminopropylcarb...)
Affinity DataIC50:  6nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285479(10,12-Dimethyl-tetradecanoic acid [6-[1,2-dihydrox...)
Affinity DataIC50:  7nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285491(10,12-Dimethyl-tetradecanoic acid [6-[1,2-dihydrox...)
Affinity DataIC50:  7nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499797(CHEMBL3742052)
Affinity DataIC50:  7.32nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285475(1N-[23-[1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-20...)
Affinity DataIC50:  9nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499793(CHEMBL3739474)
Affinity DataIC50:  9.53nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285481(10,12-Dimethyl-tetradecanoic acid {3-(3-amino-1-hy...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289909(1N-[3-[3-(1,5-diaminopentylcarboxamido)-1-hydroxyp...)
Affinity DataIC50:  10nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289919(10,12-Dimethyl-tetradecanoic acid [3-(3-amino-1-hy...)
Affinity DataIC50:  10nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50043898(10,12-Dimethyl-tetradecanoic acid [3-(3-amino-1-hy...)
Affinity DataIC50:  10nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499808(CHEMBL3741296)
Affinity DataIC50:  11.5nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499809(CHEMBL3741220)
Affinity DataIC50:  13.2nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499807(CHEMBL3740280)
Affinity DataIC50:  14.1nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289918(1N-[3-(3-aminomethylcarboxamido-1-hydroxypropyl)-6...)
Affinity DataIC50:  15nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50491851(CHEMBL2387203)
Affinity DataIC50:  18nMAssay Description:Inhibition of wild type Candida albicans 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289913(1N-[3-[3-(4-aminobutylcarboxamido)-1-hydroxypropyl...)
Affinity DataIC50:  20nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499799(CHEMBL3741985)
Affinity DataIC50:  22.2nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499794(CHEMBL3741163)
Affinity DataIC50:  24.5nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289920(1N-[3-[3-(2-aminoethylcarboxamido)-1-hydroxypropyl...)
Affinity DataIC50:  25nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
TBA

Curated by ChEMBL
LigandPNGBDBM50290785(CHEMBL406357 | Pneumocandin analogue)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of 1,3-beta-glucan synthase in Candida albicans membrane assay.More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289911(1N-[3-[3-(1,2-diaminoethylcarboxamido)-1-hydroxypr...)
Affinity DataIC50:  30nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
TBA

Curated by ChEMBL
LigandPNGBDBM50290778(CHEMBL414690 | Pneumocandin analogue)
Affinity DataIC50:  35nMAssay Description:In vitro inhibition of 1,3-beta-glucan synthase in Candida albicans membrane assay.More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50491850(CHEMBL2387205)
Affinity DataIC50:  35nMAssay Description:Inhibition of wild type Candida albicans 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50491847(CHEMBL3037784)
Affinity DataIC50:  36nMAssay Description:Inhibition of wild type Candida albicans 1,3-beta-D-glucan synthase using UDP[6,3H]-glucose as substrate after 60 mins by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285478(1N-{20-[2-(6-aminohexylcarbamoyl)-1-hydroxyethyl]-...)
Affinity DataIC50:  38nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
TBA

Curated by ChEMBL
LigandPNGBDBM50290798(CHEMBL268721 | Pneumocandin analogue)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of 1,3-beta-glucan synthase in Candida albicans membrane assay.More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
TBA

Curated by ChEMBL
LigandPNGBDBM50290784(CHEMBL413522 | Pneumocandin analogue)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of 1,3-beta-glucan synthase in Candida albicans membrane assay.More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289915(1N-[3-[3-(3-aminopropylcarboxamido)-1-hydroxypropy...)
Affinity DataIC50:  50nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499811(CHEMBL3742174)
Affinity DataIC50:  56.5nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase(Candida glabrata)
TBA

Curated by ChEMBL
LigandPNGBDBM50289912(1N-[3-[3-(1,3-diaminopropylcarboxamido)-1-hydroxyp...)
Affinity DataIC50:  60nMAssay Description:Inhibition of 1,3-beta-glucan synthaseMore data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
TBA

Curated by ChEMBL
LigandPNGBDBM50290792(CHEMBL441213 | Pneumocandin analogue)
Affinity DataIC50:  60nMAssay Description:In vitro inhibition of 1,3-beta-glucan synthase in Candida albicans membrane assay.More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
TBA

Curated by ChEMBL
LigandPNGBDBM50290777(CHEMBL428264 | Pneumocandin analogue)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of 1,3-beta-glucan synthase in Candida albicans membrane assay.More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50043897(10,12-Dimethyl-tetradecanoic acid [3-(2-carbamoyl-...)
Affinity DataIC50:  70nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
TBA

Curated by ChEMBL
LigandPNGBDBM50290797(CHEMBL267988 | Pneumocandin analogue)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of 1,3-beta-glucan synthase in Candida albicans membrane assay.More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
TBA

Curated by ChEMBL
LigandPNGBDBM50290803(CHEMBL407395 | Pneumocandin analogue)
Affinity DataIC50:  70nMAssay Description:In vitro inhibition of 1,3-beta-glucan synthase in Candida albicans membrane assay.More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-glucan synthase(Candida albicans (Yeast))
TBA

Curated by ChEMBL
LigandPNGBDBM50285493(10,12-Dimethyl-tetradecanoic acid {3-(2-carbamoyl-...)
Affinity DataIC50:  70nMAssay Description:Tested for inhibition of Beta-1,3-glucan synthase using a crude membrane of Candida albicans (MY 1208).More data for this Ligand-Target Pair
In DepthDetails Article
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499805(CHEMBL3741171)
Affinity DataIC50:  71.9nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Candida albicans)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50499792(CHEMBL3739756)
Affinity DataIC50:  74.8nMAssay Description:Displacement of UDP-[3H]glucose from beta-1,3-glucan synthase in Candida albicans MY1055 microsomal membranes incubated for 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target1,3-beta-glucan synthase component GSC2(Saccharomyces cerevisiae)
TBA

Curated by ChEMBL
LigandPNGBDBM50290793(CHEMBL410837 | Pneumocandin analogue)
Affinity DataIC50:  80nMAssay Description:In vitro inhibition of 1,3-beta-glucan synthase in Candida albicans membrane assay.More data for this Ligand-Target Pair
In DepthDetails Article
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