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Found 19 with Last Name = 'aidhen' and Initial = 'is'
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50038649(2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50038649(2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...)
Affinity DataIC50:  800nMAssay Description:Inhibition of COX-1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207307(CHEMBL3977578)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50038649(2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207302(CHEMBL3962191)
Affinity DataIC50:  6.30E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207309(CHEMBL71115)
Affinity DataIC50:  7.10E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207308(CHEMBL3958911)
Affinity DataIC50:  9.30E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207306(CHEMBL2140153)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207305(CHEMBL3889873)
Affinity DataIC50:  9.70E+3nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207310(CHEMBL3923896)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207311(CHEMBL3951603)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207304(CHEMBL3927559)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of mPGES1 in human HeLa cells assessed as reduction in TNF-alpha induced PGE2 production preincubated for 2 hrs followed by TNF-alpha addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207308(CHEMBL3958911)
Affinity DataIC50:  2.09E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50207302(CHEMBL3962191)
Affinity DataIC50:  2.28E+4nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 assessed as decrease in 5-HPETE production preincubated with enzyme followed...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E synthase(Homo sapiens (Human))
Bhupat And Jyoti Mehta School Of Biosciences

Curated by ChEMBL
LigandPNGBDBM50038649(2-(6-(4-chlorophenyl)-2,2-dimethyl-7-phenyl-2,3-di...)
Affinity DataEC50:  100nMAssay Description:Inhibition of mPGES1 in human A549 cells assessed as reduction in PGE2 productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBDNF/NT-3 growth factors receptor(Homo sapiens (Human))
Indian Institute Of Technology Madras

Curated by ChEMBL
LigandPNGBDBM50508282(CHEMBL4471556)
Affinity DataEC50:  87nMAssay Description:Agonist activity at EGFP-fused TrkB receptor (unknown origin) expressed in HEK293T cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLuciferin 4-monooxygenase(Photinus pyralis)
Indian Institute Of Technology Madras

Curated by ChEMBL
LigandPNGBDBM50099066(CHEMBL279115 | phorbol 13-acetate 12-myristate)
Affinity DataEC50:  10nMAssay Description:Activation of firefly luciferase activity expressed in HEK293T cells after 6 hrs by luminescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity nerve growth factor receptor(Homo sapiens (Human))
Indian Institute Of Technology Madras

Curated by ChEMBL
LigandPNGBDBM50508282(CHEMBL4471556)
Affinity DataEC50:  667nMAssay Description:Agonist activity at RFP-fused TrkA receptor (unknown origin) expressed in HEK293T cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed