TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DataKi: 19nM ΔG°: -43.6kJ/mole IC50: 4nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DataKi: 36nM ΔG°: -42.1kJ/mole IC50: 17nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataEC50: 480nMAssay Description:Agonist activity at human TRPC5 stably expressed in T-REx-293 cells assessed as increase in calcium flux by Fura-2AM dye based fluorescence plate rea...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataEC50: 1.25E+3nMAssay Description:Agonist activity at human TRPC5 stably expressed in T-REx-293 cells assessed as increase in calcium flux by Fura-2AM dye based fluorescence plate rea...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetShort transient receptor potential channel 5(Homo sapiens (Human))
National Cancer Institute
Curated by ChEMBL
National Cancer Institute
Curated by ChEMBL
Affinity DataEC50: 7.60nMAssay Description:Agonist activity at human TRPC5 stably expressed in HEK293 cells assessed as increase in calcium flux by Fura-2AM dye based fluorescence plate reader...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
The Johns Hopkins University
The Johns Hopkins University
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair