TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 7.94E+4nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: <1.00E+5nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 3.98E+5nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Newcastle University Centre For Cancer
Curated by ChEMBL
Newcastle University Centre For Cancer
Curated by ChEMBL
Affinity DataIC50: 5.01E+5nMAssay Description:Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in baculovirus-infected Sf9 cells incubated for 30 mins in presence ...More data for this Ligand-Target Pair
Affinity DataKd: 5.00E+4nMAssay Description:Binding affinity to full-length human CDK2 expressed in Escherichia coli BL21 (DE3) pLysS cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 3.50E+5nMAssay Description:Binding affinity to full-length human CDK2 expressed in Escherichia coli BL21 (DE3) pLysS cells by isothermal titration calorimetryMore data for this Ligand-Target Pair