TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibitory concentration to inhibit Ser396 phosphorylation of tau, a natural substrate of GSK-3 in SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 0.800nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase growth in mouse fibroblasts (NIH 3T3)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration to inhibit Ser396 phosphorylation of tau, a natural substrate of GSK-3 in SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 1.90nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 2nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Lilly Research Laboratories
Curated by ChEMBL
Lilly Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibitory concentration to inhibit Ser396 phosphorylation of tau, a natural substrate of GSK-3 in SY5Y cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:In vitro inhibition of transforming growth factor- beta dependent luciferase production in mink lung cells (p3TP Lux)More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibitory concentration against the Glycogen synthase kinase-3 More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of ATP/[gamma-33P]ATP....More data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant Mitogen activated protein kinase p38 alpha activity using ATP[gamma-33P] and EGFR 21mer-peptideMore data for this Ligand-Target Pair
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human recombinant p38alphaMore data for this Ligand-Target Pair