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Found 141 with Last Name = 'anderson' and Initial = 'h'
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254766(2-(3-(2,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254687(CHEMBL464032 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254841(2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at human EP3 receptor assessed as cAMP production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254883(CHEMBL479434 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  0.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254728(CHEMBL465947 | N-(4-methoxyphenylsulfonyl)-2-(3-(n...)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254520(CHEMBL466184 | N-(3,4-difluorophenylsulfonyl)-2-(3...)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50:  1nMAssay Description:Antagonist activity at human EP3 receptor assessed as cAMP production by cell-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254841(2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254640(CHEMBL482379 | N-(2,5-dimethoxyphenylsulfonyl)-2-(...)
Affinity DataIC50:  1.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254841(2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254768(CHEMBL518396 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  1.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254641(CHEMBL482380 | N-(2-chlorophenylsulfonyl)-2-(3-(na...)
Affinity DataIC50:  1.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254880(CHEMBL520741 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  1.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255058(CHEMBL479427 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  1.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254797(2-(3-(2-chloro-4-fluorophenylthio)-1H-indol-4-ylox...)
Affinity DataIC50:  1.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254767(CHEMBL464271 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  1.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254686(CHEMBL464031 | N-(3-chlorophenylsulfonyl)-2-(3-(na...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254520(CHEMBL466184 | N-(3,4-difluorophenylsulfonyl)-2-(3...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Mus musculus (Mouse))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50:  2nMAssay Description:Displacement of [3H]PGE2 from mouse EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254686(CHEMBL464031 | N-(3-chlorophenylsulfonyl)-2-(3-(na...)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254730(2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(ph...)
Affinity DataIC50:  2.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254643(CHEMBL481589 | N-(3,5-dichlorophenylsulfonyl)-2-(3...)
Affinity DataIC50:  2.30nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Staphylococcus aureus)
Biota Holdings

Curated by ChEMBL
LigandPNGBDBM50494813(CHEMBL3094348)
Affinity DataIC50:  2.38nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase ATPase subunit GyrA2/GyrB2 after 60 mins by malachite green staining assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254924(CHEMBL465923 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  2.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254797(2-(3-(2-chloro-4-fluorophenylthio)-1H-indol-4-ylox...)
Affinity DataIC50:  2.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254838(CHEMBL481582 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  2.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254642(2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(th...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254473(4,5-Dichlorothiophene-2-sulfonic Acid[2-(3-Naphtha...)
Affinity DataIC50:  3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254882(2-(3-(4-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5...)
Affinity DataIC50:  3.40nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254964(CHEMBL517180 | N-(3,4-difluorophenylsulfonyl)-2-(3...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254643(CHEMBL481589 | N-(3,5-dichlorophenylsulfonyl)-2-(3...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254881(2-(3-(4-(2-amino-2-oxoethyl)phenylthio)-1H-indol-4...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254729(CHEMBL517165 | N-(5-chlorothiophen-2-ylsulfonyl)-2...)
Affinity DataIC50:  3.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254839(CHEMBL520933 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  3.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255026(CHEMBL480992 | N-(3,5-difluorophenylsulfonyl)-2-(3...)
Affinity DataIC50:  3.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254882(2-(3-(4-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5...)
Affinity DataIC50:  4.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254684(CHEMBL481004 | N-(3,5-difluorophenylsulfonyl)-2-(3...)
Affinity DataIC50:  4.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254729(CHEMBL517165 | N-(5-chlorothiophen-2-ylsulfonyl)-2...)
Affinity DataIC50:  4.5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254647(2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50:  4.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254839(CHEMBL520933 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  4.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254689(2-(3-(4-(2-amino-2-oxoethyl)phenylsulfonyl)-1H-ind...)
Affinity DataIC50:  5nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254923(CHEMBL518110 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254768(CHEMBL518396 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  5.20nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255092(2-(3-(2,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...)
Affinity DataIC50:  5.60nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255094(CHEMBL518109 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  5.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254684(CHEMBL481004 | N-(3,5-difluorophenylsulfonyl)-2-(3...)
Affinity DataIC50:  5.70nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254798(2-(3-(2-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5...)
Affinity DataIC50:  5.80nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50255028(CHEMBL520425 | N-(3-chlorophenylsulfonyl)-2-(3-(na...)
Affinity DataIC50:  5.90nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50254475(CHEMBL466595 | N-(4,5-dichlorothiophen-2-ylsulfony...)
Affinity DataIC50:  6.10nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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