TargetEnoyl-[acyl-carrier-protein] reductase [NADH](Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University Of London
Curated by ChEMBL
University Of London
Curated by ChEMBL
Affinity DataKi: 2.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis inhAMore data for this Ligand-Target Pair
Affinity DataKi: 2.58E+3nMAssay Description:Non-competitive inhibition of Plasmodium falciparum FabI using NADH as cofactor by Michaelis-Menten steady state analysisMore data for this Ligand-Target Pair
Affinity DataKi: 2.90E+3nMAssay Description:Non-competitive inhibition of Plasmodium falciparum FabI using crotonyl-CoA as substrate by Michaelis-Menten steady state analysisMore data for this Ligand-Target Pair
Target3-hydroxyacyl-[acyl-carrier-protein] dehydratase(Plasmodium falciparum)
University Of London
Curated by ChEMBL
University Of London
Curated by ChEMBL
Affinity DataKi: 4.80E+3nMAssay Description:Competitive inhibition of Plasmodium falciparum FabZ using crotonyl-CoA as substrate by Michaelis-Menten steady state analysisMore data for this Ligand-Target Pair
Target3-oxoacyl-acyl-carrier protein reductase(Plasmodium falciparum)
University Of London
Curated by ChEMBL
University Of London
Curated by ChEMBL
Affinity DataKi: 6.00E+3nMAssay Description:Non-competitive inhibition of Plasmodium falciparum FabG using NADH as cofactor by Michaelis-Menten steady state analysisMore data for this Ligand-Target Pair
Target3-oxoacyl-acyl-carrier protein reductase(Plasmodium falciparum)
University Of London
Curated by ChEMBL
University Of London
Curated by ChEMBL
Affinity DataKi: 1.43E+4nMAssay Description:Competitive inhibition of Plasmodium falciparum FabG using acetoacetyl-CoA as substrate by Michaelis-Menten steady state analysisMore data for this Ligand-Target Pair
Affinity DataIC50: <0.5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Piramal Life Sciences
Curated by ChEMBL
Piramal Life Sciences
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of p38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of CDK1/cyclinB (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
TargetDipeptidase 1(Homo sapiens (Human))
The Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins
Curated by ChEMBL
The Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Concentration required to inhibit renal dipeptidase (RDP) by 50% in crude lysates prepared from human colon cancerMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
TargetDipeptidase 1(Homo sapiens (Human))
The Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins
Curated by ChEMBL
The Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins
Curated by ChEMBL
Affinity DataIC50: 6nMAssay Description:Concentration required to inhibit renal dipeptidase (RDP) by 50% in crude lysates prepared from human colon cancerMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
TargetDipeptidase 1(Homo sapiens (Human))
The Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins
Curated by ChEMBL
The Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Concentration required to inhibit renal dipeptidase (RDP) by 50% in crude lysates prepared from human colon cancerMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity after 100 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of Mycobacterium smegmatis DNA gyrase B ATPase activity assessed as inorganic phosphate release using ATP as substrate by colorimetric ana...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair
Affinity DataIC50: <10nMAssay Description:The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...More data for this Ligand-Target Pair